Results 11 to 20 of about 434,321 (269)

Myeloid sarcoma as a manifestation of acute myeloid leukemia

open access: yesBaylor University Medical Center Proceedings, 2021
We report a case of a 43-year-old man who presented with dyspnea because of large bilateral pleural effusions and imaging findings of a large periaortic mass with compression of the esophagus and left atrium. Subsequent soft tissue biopsy was consistent with myeloid sarcoma, and bone marrow biopsy was consistent with acute myeloid leukemia.
Lewis Woods, Jerry Fan, Hameed Ali
openaire   +3 more sources

Myeloid Derived Suppressor Cells in Chronic Myeloid Leukemia [PDF]

open access: yesFrontiers in Oncology, 2015
The suppression of the immune system creates a permissive environment for development and progression of cancer. One population of immunosuppressive cells that have become the focus of intense study is myeloid derived suppressor cells (MDSCs), immature myeloid cells able to induce immune-escape, angiogenesis, and tumor progression.
Cesarina eGiallongo   +7 more
openaire   +6 more sources

Ontogeny of Myeloid Cells [PDF]

open access: yesFrontiers in Immunology, 2014
Granulocytes, monocytes, macrophages, and dendritic cells (DCs) represent a subgroup of leukocytes, collectively called myeloid cells. During the embryonic development of mammalians, myelopoiesis occurs in a stepwise fashion that begins in the yolk sac and ends up in the bone marrow (BM).
Ismé eDe Kleer   +4 more
openaire   +6 more sources

Pediatric chronic myeloid leukemia in myeloid blast crisis

open access: yesAutopsy Case Reports, 2023
Chronic myeloid leukemia (CML) accounts for 2-3% of childhood leukemias. About 5% of cases present in a blastic phase of CML which clinically and morphologically mimics more common acute leukemias of childhood. We report a case of a 3-year-old male who presented with gradual onset swelling of the abdomen and extremities along with generalized weakness.
Biswajit Dey, Anirban Dutta
openaire   +3 more sources

Philadelphia Chromosome-Positive de Novo AML or Blast Phase CML? Case Report and Short Literature Review [PDF]

open access: yesDocumenta Haematologica, 2023
The BCR::ABL1 translocation and the accompanying Philadelphia chromosome represents the first mutation which defined a disease, chronic myeloid leukemia.
Dan-Sebastian SOARE   +10 more
doaj   +1 more source

The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity

open access: yesNature Communications, 2016
Dendritic cells are antigen-presenting cells consisting of distinct subsets originating from different lineages. Here, the authors identify the subsets of dendritic cells populating the tumour tissue in both mice and humans and find they have opposing ...
Damya Laoui   +16 more
doaj   +1 more source

Murine Liver Myeloid Cell Isolation Protocol

open access: yesBio-Protocol, 2015
In homeostasis, the liver is critical for the metabolism of nutrients including sugars, lipids, proteins and iron, for the clearance of toxins, and to induce immune tolerance to gut-derived antigens.
Benoit Stijlemans   +8 more
doaj   +1 more source

Understanding the glioblastoma immune microenvironment as basis for the development of new immunotherapeutic strategies

open access: yeseLife, 2020
Cancer immunotherapy by immune checkpoint blockade has proven its great potential by saving the lives of a proportion of late stage patients with immunogenic tumor types.
Ana Rita Pombo Antunes   +5 more
doaj   +1 more source

Molecular Measurable Residual Disease Testing of Blood During AML Cytotoxic Therapy for Early Prediction of Clinical Response

open access: yesFrontiers in Oncology, 2019
Measurable residual disease (MRD) testing after initial chemotherapy treatment can predict relapse and survival in acute myeloid leukemia (AML). However, it has not been established if repeat molecular or genetic testing during chemotherapy can offer ...
Hong Yuen Wong   +16 more
doaj   +1 more source

Conservative Management of Presumed Fetal Anemia Secondary to Maternal Chemotherapy for Acute Myeloid Leukemia

open access: yesAmerican Journal of Perinatology Reports, 2021
Acute myeloid leukemia occurs rarely during pregnancy. When it is diagnosed remote from term, treatment in the form of daunorubicin plus cytarabine induction with consolidative cytarabine is typically undertaken after the first trimester. There is little
Christina M. Nowik   +2 more
doaj   +1 more source

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