Results 41 to 50 of about 919,731 (432)
Frontiers in Oncology, 2019 Measurable residual disease (MRD) testing after initial chemotherapy treatment can predict relapse and survival in acute myeloid leukemia (AML). However, it has not been established if repeat molecular or genetic testing during chemotherapy can offer ...
Hong Yuen Wong +16 more
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Macrophage Subsets in Obesity, Aligning the Liver and Adipose Tissue
Frontiers in Endocrinology, 2020 The increasing prevalence of obesity is accompanied by a rising incidence in metabolic syndrome and related pathologies such as non-alcoholic fatty liver disease. Macrophages are hypothesized to play central roles in these diseases, through their role as
Anneleen Remmerie +6 more
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Genomic Classification and Prognosis in Acute Myeloid Leukemia.
New England Journal of Medicine, 2016 BACKGROUND Recent studies have provided a detailed census of genes that are mutated in acute myeloid leukemia (AML). Our next challenge is to understand how this genetic diversity defines the pathophysiology of AML and informs clinical practice ...
E. Papaemmanuil +26 more
semanticscholar +1 more source
Diamonds in the Rough: Harnessing Tumor-Associated Myeloid Cells for Cancer Therapy
Frontiers in Immunology, 2018 Therapeutic approaches that engage immune cells to treat cancer are becoming increasingly utilized in the clinics and demonstrated durable clinical benefit in several solid tumor types.
Emile J. Clappaert +9 more
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Frontiers in Oncology, 2022 IntroductionCytogenetic analysis is important for stratifying patients with various neoplasms. We explored the use of targeted next generation sequencing (NGS) in detecting chromosomal structural abnormalities or copy number variations (CNVs) in patients
Andrew Ip +24 more
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Antigen presenting capacity of murine splenic myeloid cells [PDF]
, 2017 BACKGROUND: The spleen is an important site for hematopoiesis. It supports development of myeloid cells from bone marrow-derived precursors entering from blood. Myeloid subsets in spleen are not well characterised although dendritic cell (DC) subsets are
Hey, Ying-Ying +2 more
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The mechanics of myeloid cells
Biology of the Cell, 2020 AbstractThe effects of cell size, shape and deformability on cellular function have long been a topic of interest. Recently, mechanical phenotyping technologies capable of analysing large numbers of cells in real time have become available. This has important implications for biology and medicine, especially haemato‐oncology and immunology, as immune ...
Mariana J. Kaplan +8 more
openaire +6 more sources
Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells
Nature Communications, 2016 Tissue-resident macrophages are mostly derived from embryonic progenitors. Scott et al. develop a mouse model to specifically deplete Kupffer cells (KC) in vivoand show that monocyte-derived cells can repopulate KC niche and behave similar to their ...
Charlotte L. Scott +13 more
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Adoptive Transfer of Monocytes Sorted from Bone Marrow
Bio-Protocol, 2019 Inflammatory Ly6Chi monocytes can give rise to distinct mononuclear myeloid cells in the tumor microenvironment, such as monocytic myeloid-derived suppressor cells (Mo-MDSC), immature macrophages, M2-like tumor-associated macrophages (TAMs), M1-like TAMs
Damya Laoui +4 more
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Advances in acute myeloid leukemia
British medical journal, 2021 Acute myeloid leukemia (AML) is an uncommon but potentially catastrophic diagnosis with historically high mortality rates. The standard of care treatment remained unchanged for decades; however, recent discoveries of molecular drivers of leukemogenesis ...
L. Newell, R. Cook
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