Association study of uncoupling protein 2-866G/A (rs659366) gene polymorphism and serum myeloperoxidase with cardiovascular disease in type 2 diabetic patients [PDF]
Egyptian Journal of Medical Research, 2023 Diabetic cardiovascular diseases are leading causes of death. In diabetic patients, oxidative stress is key event in cardiovascular disease (CVD) development.
Hanan Mohamed Farhan +6 more
doaj +1 more source
Myeloperoxidase: a new target for the treatment of stroke?
Neural Regeneration Research, 2022 Myeloperoxidase is an important inflammatory factor in the myeloid system, primarily expressed in neutrophils and microglia. Myeloperoxidase and its active products participate in the occurrence and development of hemorrhagic and ischemic stroke ...
Yun-Chang Wang +9 more
doaj +1 more source
Inhibition of Myeloperoxidase Activity in Cystic Fibrosis Sputum by Peptide Inhibitor of Complement C1 (PIC1). [PDF]
PLoS ONE, 2017 Myeloperoxidase is the major peroxidase enzyme in neutrophil granules and implicated in contributing to inflammatory lung damage in cystic fibrosis. Free myeloperoxidase is present in cystic fibrosis lung fluid and generates hypochlorous acid.
Pamela S Hair +3 more
doaj +1 more source
Frontiers in Veterinary Science, 2022 Laminitis is a pathology of the equine digit leading to a failure of the dermo-epidermal interface. Neutrophil activation is recognized as a major factor in SIRS-associated laminitis.
Nazare Storms +6 more
doaj +1 more source
The relation of serum myeloperoxidase to disease progression and mortality in patients with chronic obstructive pulmonary disease (COPD). [PDF]
PLoS ONE, 2013 Myeloperoxidase is a strong oxidant stored in primary granules of neutrophils with potent antibacterial and proatherogenic properties. Myeloperoxidase has been implicated in the pathogenesis of chronic obstructive pulmonary disease (COPD).
Hye Yun Park +6 more
doaj +1 more source
Frontiers in Immunology, 2023 Myeloperoxidase (MPO) is a cationic leukocyte haloperoxidase and together with other proteins, they possess activities against various microorganisms and are involved in extracellular trap (ET) formation.
Qiujie Gan +12 more
doaj +1 more source
Animal Models of ANCA Associated Vasculitis
Frontiers in Immunology, 2020 Anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) is a rare and severe autoimmune multisystemic disease. Its pathogenesis involves multiple arms of the immune system, as well as complex interactions between immune cells and target ...
Lani Shochet +7 more
doaj +1 more source
Peculiarities of Airway Inflammation and Lipid Peroxidation in the Development of Hyperosmotic Airway Hyperresponsiveness in Patients with Asthma [PDF]
International Journal of Biomedicine, 2016 The aim of our study was to evaluate the role of airway cellular inflammation and the lipid peroxidation level in the development of airway hyperresponsiveness (AHR) to inhalation of hypertonic saline (IHS).
Alexey B. Pirogov +6 more
doaj +1 more source
Myeloperoxidase G-463A and CYBA C242T genetic variants in gestational diabetes mellitus
Vascular Biology, 2023 Oxidative stress plays an important role in the pathophysiology of gestational diabetes mellitus (GDM). We investigated the relationship between NADPH oxidase p22phox subunit (CYBA) C242T (rs4673) and myeloperoxidase (MPO) G-463A (rs2333227) genetic ...
Chenyu Jiang +10 more
doaj +1 more source
Journal of International Clinical Dental Research Organization, 2021 Background: Smoking is the second strongest modifiable risk factor for periodontal disease. Tissue destruction might result from matrix metalloproteinase (MMP)/tissue inhibitors of MMP (TIMP) imbalance in the diseased tissues.
Deepti Gattani +3 more
doaj +1 more source