Results 31 to 40 of about 145,768 (387)

Association between serum myeloperoxidase levels and coronary artery disease in patients without diabetes, hypertension, obesity, and hyperlipidemia

Advanced Biomedical Research, 2016
Background: Myeloperoxidase (MPO) is an enzyme, elevated in the atheroma and serum of a patient with atherosclerotic vessels. The aim of this study is to investigate whether the serum MPO level is related to the presence of plaque in patients without ...
Zahra Hasanpour, Shaghayegh Haghjooy Javanmard, Maryam Gharaaty, Masoumeh Sadeghi   +3 more
doaj   +1 more source

Visceral leishmaniasis patients display altered composition and maturity of neutrophils as well as impaired neutrophil effector functions [PDF]

, 2016
Immunologically, active visceral leishmaniasis (VL) is characterised by profound immunosuppression, severe systemic inflammatory responses and an impaired capacity to control parasite replication.
Adem, E, Cruz Cervera, E, Diro, E, Getahun, M, Hailu, A, Kropf, P, Lemma, M, Melkamu, R, Mengesha, B, Mesfin, G, Modolell, M, Muller, I, Munder, M, Skhedy, Z, Tajebe, F, Takele, Y, Van der Auwera, G, Yardley, V, Yeshanew, A, Yizengaw, E   +19 more
core   +3 more sources

Myeloperoxidase and related biomarkers are suggestive footprints of endothelial microvascular inflammation in HFpEF patients

ESC Heart Failure, 2020
In heart failure (HF) with preserved ejection fraction (HFpEF), microvascular inflammation is proposed as an underlying mechanism. Myeloperoxidase (MPO) is associated with vascular dysfunction and prognosis in congestive HF.
C. Hage, E. Michaëlsson, B. Kull, T. Miliotis, S. Svedlund, C. Linde, E. Donal, J. Daubert, L. Gan, L. Lund   +9 more
semanticscholar   +1 more source

Increased levels of MMP-3, MMP-9 and MPO represent predictors of in-stent restenosis, while increased levels of ADMA, LCAT, ApoE and ApoD predict bare metal stent patency

Biomedical Papers, 2015
Aims: We sought to identify biochemical predictors that indicate susceptibility to in-stent restenosis (ISR) after coronary artery bare-metal stenting.
Leos Pleva, Pavlina Kusnierova, Pavlina Plevova, Jana Zapletalova, Michal Karpisek, Lucie Faldynova, Petra Kovarova, Pavel Kukla   +7 more
doaj   +1 more source

Biological Variation of Myeloperoxidase [PDF]

Clinical Chemistry, 2008
Myeloperoxidase (MPO)1 has been shown to play a role in the pathogenesis of coronary artery disease. It is released from activated neutrophils at sites of vascular damage and has been shown to increase in atherosclerotic plaques before the onset of myocardial injury (1).
Dednam, Marita, Vorster, Barend Christiaan, Ubbink, Johan B.   +2 more
openaire   +4 more sources

Recombinant Myeloperoxidase as a New Class of Antimicrobial Agents

Microbiology Spectrum, 2022
Heme-containing peroxidases are widely distributed in the animal and plant kingdoms and play an important role in host defense by generating potent oxidants.
Zehong Cao, Guangjie Cheng
doaj   +1 more source

Pharmacology and clinical drug candidates in redox medicine [PDF]

, 2015
SIGNIFICANCE Oxidative stress is suggested to be a disease mechanism common to a wide range of disorders affecting human health. However, so far, the pharmacotherapeutic exploitation of this, for example, based on chemical scavenging of pro-oxidant ...
Casas, Ana I, Cuadrado, Antonio, Dao, V Thao-Vi, Di Lisa, Fabio, Ghezzi, Pietro, Jaquet, Vincent, Kaludercic, Nina, Maghzal, Ghassan J, Robledinos-Anton, Natalia, Schmidt, Harald H H W, Seredenina, Tamara, Stocker, Roland   +11 more
core   +2 more sources

Extra medullar Granulocytic sarcoma: a case report of an exceptional localization [PDF]

, 2020
Granulocytic sarcoma is a rare type of tumor composed of extramedullary immature cells. The breast location is very rare; it accounts for less than 8% of cases.
Khaled, Rahal, Malek, Bouhani, Olfa, Adouni, Olfa, Jaidane, Riadh, Chargui, Saida, Sakhri   +5 more
core   +2 more sources

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

Journal of Cell Biology, 2010
Neutrophil elastase escapes azurophilic granules, translocates to the nucleus, and degrades histones to promote chromatin decondensation necessary for NET formation.
V. Papayannopoulos, Kathleen D. Metzler, Abdul Hakkim, A. Zychlinsky   +3 more
semanticscholar   +1 more source

Hereditary myeloperoxidase deficiency [PDF]

Blood, 1979
The functional properties of granulocytes in a diabetic patient deficient in myeloperoxidase (MPO) were compared with those of granulocytes in healthy subjects. The granulocytes of this patient had normal phagocytic activity. The microbicidal activity of the granulocytes was partially diminished with regard to Staphylococcus aureus and was almost nil ...
Gaston Boreux, Athanassios Papathanassiou, Paul Roth, P. A. Miescher, Petr Cech   +4 more
openaire   +4 more sources