Results 51 to 60 of about 81,511 (306)

Neutrophil NET Formation with Microbial Stimuli Requires Late Stage NADPH Oxidase Activity

Antioxidants, 2021
Neutrophils respond to a range of stimuli by releasing extracellular traps (NETs), a mesh consisting of chromatin plus granule and cytoplasmic proteins.
Heather A. Parker, Harry M. Jones, Christopher D. Kaldor, Mark B. Hampton, Christine C. Winterbourn   +4 more
doaj   +1 more source

Hereditary myeloperoxidase deficiency [PDF]

Blood, 1981
Subjects with neutrophil myeloperoxidase (MPO) deficiency have been rarely reported. In part this may be due to the lack of a simple screening technique that would detect them. With the routine use of a cytochemical leukocyte differential counter that employs MPO stains, over a 40-mo a period 8 unrelated probands with partial MPO-deficiency and one ...
M, Kitahara, H J, Eyre, Y, Simonian, C L, Atkin, S J, Hasstedt   +4 more
openaire   +3 more sources

Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Hospitalized in the United States

Arthritis Care &Research, EarlyView.
Objective Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race and ethnicity and household income are associated with severe AAV disease and renal outcomes among
Roberto Alejandro Valdovinos, William Daniel Soulsby III, Emily von Scheven   +2 more
wiley   +1 more source

Development of a Microfluidic Paper-Based Analytical Device for Myeloperoxidase Detection in Periodontitis

Dentistry Journal
Objectives: To develop a microfluidic paper-based analytical device (μPAD) that identifies myeloperoxidase (MPO) levels in the saliva of healthy patients and those with periodontal disease. Materials and Methods: A platform similar to a 96-well plate was
Juliane Caroline Leão, Thiago Mazzu, Vitor Leão, Paola Gomes Souza, Nathalya Maria Vilela Moura, Emanuel Carrilho, Mario Taba   +6 more
doaj   +1 more source

Temporal Immune and Metabolic Shifts Drive the Anti‐Tumor Efficacy of Resiquimod‐Loaded Nanoparticles in Peritoneal Carcinomatosis

Advanced Healthcare Materials, EarlyView.
Peritoneal carcinomatosis is a hard‐to‐treat spread of abdominal cancers that often returns after therapy. Nanoparticles were developed to retain an immune‐boosting drug in the abdomen. When combined with chemotherapy in mice, this approach eliminated tumors in many cases and prevented recurrence, helping the immune system mount a stronger, longer ...
Vanessa Chan, Po‐Han Chao, XuXin Sun, Jun Han, Sarah MacPherson, Lucas J. Andrew, Noah Y. Brittain, Tien Do, Marcel B. Bally, Julian J. Lum, Shyh‐Dar Li   +10 more
wiley   +1 more source

Somatostatin Mitigates Gastric Mucosal Damage Induced by LPS in a Male Wistar Rat Model of Sepsis

Biomolecules
Upper gastrointestinal bleeding from erosive gastritis remains associated with high mortality in septic or postoperative patients. While stress ulcer bleeding has declined, it still occurs in septic patients and is considered a manifestation of ...
Sergio D. Paredes, Jorge Hernández-Cortés, Farzin Falahat, Lisa Rancan, Javier Arias-Díaz, Elena Vara   +5 more
doaj   +1 more source

C-Reactive Protein Is Elevated Only in High Creatine Kinase Responders to Muscle Damaging Exercise

Frontiers in Physiology, 2019
The purpose of this study was to investigate if exertional rhabdomyolysis induced by an acute bout of plyometric exercise in untrained individuals was associated with histological characteristics of skeletal muscle, creatine kinase (CK) polymorphism or ...
Ashwin W. Isaacs, Filippo Macaluso, Filippo Macaluso, Filippo Macaluso, Filippo Macaluso, Carine Smith, Kathryn H. Myburgh, Kathryn H. Myburgh   +7 more
doaj   +1 more source

Low serum myeloperoxidase in autistic children with gastrointestinal disease [PDF]

, 2009
Anthony J Russo1, Arthur Krigsman2, Bryan Jepson2, Andy Wakefield21Research Director, Health Research Institute/Pfeiffer Treatment Center, Warrenville, IL, USA; 2Thoughtful House Center for Children, Austin, TX, USAAim: To assess serum myeloperoxidase ...
Arthur Krigsman, et al, Anthony J Russo, Bryan Jepson   +3 more
core  

Lonicera japonica‐Derived Nanovesicles Ameliorate Acute Lung Injury by Suppressing Neutrophil Extracellular Traps Formation in Mice

Advanced Healthcare Materials, EarlyView.
(A) Isolation and purification of LDNVs. (B) Establishment of the ALI model and LDNVs delivery. (C) Therapeutic mechanisms of LDNVs in treating ALI. This scheme figure was drawn by Figdraw, ID: IUIIO21222. ABSTRACT Acute lung injury (ALI) is a lethal respiratory disease.
Xi Lin, Jian Lin, Yezi Zhang, Xinyan Zhang, Xinghua Liu, Hongying Cao, Huan Shen, Jianming Liang, Zhenhua Dai, Siyuan Xu, Xingdong Lin   +10 more
wiley   +1 more source

Some patients with anti-myeloperoxidase autoantibodies have a C-ANCA pattern [PDF]

, 1994
Rapidly progressive glomerulonephritis with or without other signs of systemic vasculitis is often accompanied by antibodies to myeloperoxidase. Such antibodies normally produce a perinuclear pattern on ethanol-fixed neutrophils (perinuclear anti ...
B BASLUND, M SEGELMARK, Segelmark, M., J WIESLANDER, Baslund, B., Wieslander, J.   +5 more
core   +3 more sources