Results 51 to 60 of about 145,768 (387)

Uncoupling of Carbonic Anhydrase from Na-H exchanger-1 in Experimental Colitis: A Possible Mechanistic Link with Na-H Exchanger

Biomolecules, 2019
In this study, we investigated a mechanistic link between Na−H exchanger-1 (NHE-1) and carbonic anhydrase (CA) in experimental colitis induced in the rats by intrarectal administration of trinitrobenzenesulphonic acid (TNBS).
Islam Khan, Khalid Khan
doaj   +1 more source

Extracellular vesicles in heart failure – A study in patients with heart failure with preserved ejection fraction or heart failure with reduced ejection fraction characteristics undergoing elective coronary artery bypass grafting

Frontiers in Cardiovascular Medicine, 2022
AimsExtracellular vesicles (EVs) were investigated as potential biomarkers associated with heart failure (HF) pathophysiology in patients undergoing elective coronary artery bypass surgery characterized by HF phenotype.Materials and methodsPatients with ...
Dmitri Matan, Dmitri Matan, Fariborz Mobarrez, Ulrika Löfström, Ulrika Löfström, Matthias Corbascio, Mattias Ekström, Mattias Ekström, Camilla Hage, Camilla Hage, Patrik Lyngå, Bengt Persson, Maria Eriksson, Cecilia Linde, Cecilia Linde, Hans Persson, Hans Persson, Håkan Wallén, Håkan Wallén   +18 more
doaj   +1 more source

The effect of polyphenol-rich Interventions on cardiovascular risk factors in haemodialysis: A systematic review and meta-analysis [PDF]

, 2017
End-stage kidney disease is a strong risk factor for cardiovascular-specific mortality. Polyphenol-rich interventions may attenuate cardiovascular disease risk factors; however, this has not been systematically evaluated in the hemodialysis population ...
Campbell, Katrina, Itsiopoulos, Catherine, Kelly, Jaimon, Marshall, Skye, Marx, Wolfgang, Nakos, Stacey   +5 more
core   +4 more sources

Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow [PDF]

, 2013
This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
Bangash, MN, Benetti, E, Collino, M, Hinds, CJ, Patel, NSA, Pearse, RM, Thiemermann, C   +6 more
core   +2 more sources

Association of Tumor Necrosis Factor-α and Neutrophilic Inflammation in Severe Asthma

Allergology International, 2005
Background: There is evidence that neutrophils are increased in the airway of severe disease or acute exacerbations of asthma. The mechanisms by which neutrophils are recruited to the airways and contribute to the pathophysiology of asthma remain to be ...
Shinya Kikuchi, Izumi Kikuchi, Koichi Hagiwara, Minora Kanazawa, Makoto Nagata   +4 more
doaj   +1 more source

Plasma myeloperoxidase: association with atrial fibrillation progression and recurrence after catheter ablation

Frontiers in Cardiovascular Medicine, 2023
BackgroundMyeloperoxidase (MPO), released by activated neutrophils, is significantly increased in atrial fibrillation (AF). MPO may play a role in the progression of atrial fibrillation and further involved in AF recurrence after catheter ablation.
Jingmeng Liu, Changjian Lin, Taojie Zhou, Yangyang Bao, Yun Xie, Yue Wei, Qingzhi Luo, Tianyou Ling, Wenqi Pan, Ning Zhang, Lin Lu, Lin Lu, Liqun Wu, Qi Jin   +13 more
doaj   +1 more source

Attenuation of leukocyte sequestration by selective blockade of PECAM-1 or VCAM-1 in murine endotoxemia [PDF]

, 2004
Background: Molecular mechanisms regulating leukocyte sequestration into the tissue during endotoxemia and/or sepsis are still poorly understood. This in vivo study investigates the biological role of murine PECAM-1 and VCAM-1 for leukocyte sequestration
Chosay JG, Chosay JG, Christofidou-Solomidou M, D. Nolte, Dinarello CA, Essani NA, Hahne M, Hoffmann JN, Jin HK, K. Messmer, K.-D. Wolff, Khan BV, Kuebler WM, Kunkel EJ, Muchamuel T, Neumann B, Nolte D, Nolte D, Nolte D, Orosz CG, Piedboeuf B, Vaporciyan AA, Vestweber D, W.A. Muller, W.M. Kuebler, Zeintl H   +25 more
core   +1 more source

MYELOPEROXIDASE AS A MULTI-FACETED TARGET FOR CARDIOVASCULAR PROTECTION.

Antioxidants and Redox Signaling, 2019
SIGNIFICANCE Myeloperoxidase (MPO) is a heme peroxidase that is primarily expressed by neutrophils. It has the capacity to generate several reactive species, essential for its inherent antimicrobial activity and innate host defense.
C. Ramachandra, Myu Mai Ja Kp, Jasper Chua, Shuo Cong, W. Shim, D. Hausenloy   +5 more
semanticscholar   +1 more source

The inhibition of myeloperoxidase by ceruloplasmin can be reversed by anti-myeloperoxidase antibodies [PDF]

Kidney International, 1999
The purpose of this study was to characterize the recently reported inhibition of myeloperoxidase (MPO) by ceruloplasmin and to determine whether this may be disturbed in the presence of anti-MPO antibodies.Specificity of the binding between ceruloplasmin and MPO was confirmed by Western blotting and enzyme-linked immunosorbent assay (ELISA), and the ...
C. Martin Lockwood, Philip T. Chapman, Elias A. Lianos, Siân V. Griffin   +3 more
openaire   +3 more sources

Alterations of HDL particles in children with end-stage renal disease [PDF]

Journal of Medical Biochemistry, 2017
Background: Unfavorable lipid profile presents one of most important risk factor for cardiovascular disease in renal pathology. Myeloperoxidase (MPO) as enzyme which oxidizes lipoproteins and paraoxonase1 (PON1) as anti-oxidative enzyme have been ...
Stefanović Aleksandra, Ristovski-Kornic Danijela, Kotur-Stevuljević Jelena, Spasojević-Kalimanovska Vesna, Vekić Jelena, Miljković Milica, Paripović Dušan, Peco-Antić Amira, Jelić-Ivanović Zorana, Zeljković Aleksandra   +9 more
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