Results 61 to 70 of about 119,702 (326)

Association between serum myeloperoxidase levels and coronary artery disease in patients without diabetes, hypertension, obesity, and hyperlipidemia

Advanced Biomedical Research, 2016
Background: Myeloperoxidase (MPO) is an enzyme, elevated in the atheroma and serum of a patient with atherosclerotic vessels. The aim of this study is to investigate whether the serum MPO level is related to the presence of plaque in patients without ...
Zahra Hasanpour, Shaghayegh Haghjooy Javanmard, Maryam Gharaaty, Masoumeh Sadeghi   +3 more
doaj   +1 more source

Orbital pseudotumour masquerading as Wegener’s granulomatosis [PDF]

, 2015
A twenty-two year old female patient presented with new onset bilateral hard orbital masses and progressively worse tear lake problems. Computed tomography of the orbits revealed poorly differentiated bilateral orbital masses.
Fenech, Matthew, Fenech, Thomas
core  

Inflammatory bowel disease-specific autoantibodies in HLA-B27-associated spondyloarthropathies: Increased prevalence of ASCA and pANCA [PDF]

, 2004
Aims: An association between inflammatory bowel disease (IBD) and spondyloarthropathies (SpA) has repeatedly been reported. The aim of the present study was to investigate whether serologic markers of IBD, e. g.
Brumberger, V., Folwaczny, Christian, Glas, J., Gruber, R., Kellner, H., Marker-Hermann, E., Strasser, C., Török, H.-P.   +7 more
core   +1 more source

ROS Activated NETosis of Bone Marrow CD55+ Intermediate Mature Neutrophils Through HIF1α‐PADI4 Pathway to Initiate Bone Aging

Advanced Science, EarlyView.
In this study, we find CD55+ neutrophils show activated NETosis within bone marrow, induce BMSC senescence and osteogenesis inhibition, finally leading to bone aging initiation. Mechanistically, ROS synergizes with the CD55‐driven HIF1α‐PADI4 pathway to promote NETosis.
Yutong Guo, Shengjie Cui, Xi Wen, Yidi Wang, Ben Wu, Yixiang Wang, Yan Gu   +6 more
wiley   +1 more source

Bone marrow‐restricted aberrant myeloperoxidase expression in B‐acute lymphoblastic leukemia: A diagnostic dilemma and mimicry of mixed phenotype acute leukemia

eJHaem
Myeloperoxidase (MPO) is the most specific marker of the myeloid lineage, essential for diagnosing acute myeloid leukemia and mixed phenotype acute leukemia with myeloid components.
Wei J. Wang, Brandon T. Gehris, Daniel Rivera, Sibel Ak, David Feng, Wei Wang, Zhihong Hu   +6 more
doaj   +1 more source

Animal Models of ANCA Associated Vasculitis

Frontiers in Immunology, 2020
Anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) is a rare and severe autoimmune multisystemic disease. Its pathogenesis involves multiple arms of the immune system, as well as complex interactions between immune cells and target ...
Lani Shochet, Lani Shochet, Stephen Holdsworth, Stephen Holdsworth, Stephen Holdsworth, A. Richard Kitching, A. Richard Kitching, A. Richard Kitching   +7 more
doaj   +1 more source

Acute inflammatory response to contrast agent aspiration and its mechanisms in the rat lung. [PDF]

, 2019
Objectives/hypothesisContrast agent (CA) aspiration is an established complication of upper gastrointestinal and videofluoroscopic swallow studies. The underlying molecular biological mechanisms of acute response to CA aspiration in the respiratory ...
Belafsky, Peter C, Goto, Takao, Nativ-Zeltzer, Nogah, Nito, Takaharu, Sato, Taku, Ueha, Rumi, Yamasoba, Tatsuya   +6 more
core   +1 more source

BioCNTs Mediated Delivery of Systemically Mobile Small RNAs via Leaf Spray to Control Both Tomato DNA and RNA Viruses

Advanced Science, EarlyView.
A carbon nanotube‐based biopesticide system (BioCNTs) enables efficient delivery and systemic movement of RNAi molecules to control major tomato viruses. By integrating shRNA and tRNA‐like structures (TLS) with BioCNTs, this green and scalable approach achieves long‐term silencing and high antiviral efficacy through simple foliar spraying.
Xuedong Liu, Xiaofei Liang, Zipeng Cai, Zheng Liu, Xuefeng Wang, Changyong Zhou, Mengji Cao, Sijia Liu   +7 more
wiley   +1 more source

Integrated analysis of myeloperoxidase in gastric health and cancer: associations with pepsinogen levels, immune regulation, and prognosis in a large healthy population-based and TCGA cohorts

Frontiers in Immunology
BackgroundMyeloperoxidase (MPO) is a key enzyme involved in immune responses and oxidative stress, yet its roles in gastric physiology and gastric cancer remain incompletely understood.
Junteng Zhou, Qihang Kong, Xiaojing Liu, Xiaojing Liu, Yan Huang, Yan Huang, Yan Huang, Yan Huang   +7 more
doaj   +1 more source

Pathogenesis and Diagnosis of Otitis Media with ANCA-Associated Vasculitis

Allergology International, 2014
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is histologically characterized by systemic necrotizing vasculitis and is clinically classified into two phases, systemic or localized.
Naohiro Yoshida, Yukiko Iino
doaj   +1 more source