Results 11 to 20 of about 3,006,184 (303)
Pathogenesis of Myeloproliferative Disorders [PDF]
Annual Review of Pathology: Mechanisms of Disease, 2016 Myeloproliferative neoplasms (MPNs) are a set of chronic hematopoietic neoplasms with overlapping clinical and molecular features. Recent years have witnessed considerable advances in our understanding of their pathogenetic basis. Due to their protracted clinical course, the evolution to advanced hematological malignancies, and the accessibility of ...
Nangalia, J, Grinfeld, J, Green, AR
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A Gain-of-Function Mutation of JAK2 in Myeloproliferative Disorders [PDF]
New England Journal of Medicine, 2005 Róbert Královics +8 more
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Brain MRI-findings in Ph - negative myeloproliferative disorders
Терапевтический архив, 2019 Myeloproliferative disorders (MPD) are accompanied by a high proportion of thrombotic complications, which may lead to cerebrovascular disease (CVD). Aim.
M M Tanashyan +5 more
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Myelodysplastic and myeloproliferative disorders of childhood. [PDF]
Hematology Am Soc Hematol Educ Program, 2016 Hasle H.
europepmc +2 more sources
Blood, 2008 Abstract In 1951 William Dameshek classified polycythemia vera (PV), essential thombocytosis (ET), and primary myelofibrosis (PMF) as pathogenetically related myeloproliferative disorders (MPD). Subsequent studies demonstrated that PV, ET, and PMF are clonal disorders of multipotent hematopoietic progenitors.
Ross L, Levine, D Gary, Gilliland
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IL-4 Serum Level Estimation in Myeloproliferative Neoplasm Patients
مجلة مركز بحوث التقنيات الاحيائية, 2022 Back Ground: Myeloproliferative neoplasm (MPN) is a long-term blood disease that has an excess production of mature hematopoietic pluripotent stem cells in the bone marrow. In the early fifties, W.
Ahmed Rushdi Abdullah
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Myeloproliferative Neoplasms, Version 3.2022, NCCN Clinical Practice Guidelines in Oncology.
The Journal of the National Comprehensive Cancer Network, 2022 The classic Philadelphia chromosome-negative myeloproliferative neoplasms (MPN) consist of myelofibrosis, polycythemia vera, and essential thrombocythemia and are a heterogeneous group of clonal blood disorders characterized by an overproduction of blood
A. Gerds +30 more
semanticscholar +1 more source
The Thrombopoietin Receptor, MPL, Is a Therapeutic Target of Opportunity in the MPN
Frontiers in Oncology, 2021 The myeloproliferative neoplasms, polycythemia vera, essential thrombocytosis and primary myelofibrosis share driver mutations that either activate the thrombopoietin receptor, MPL, or indirectly activate it through mutations in the gene for JAK2, its ...
Jerry L. Spivak, Alison R. Moliterno
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European Heart Journal, 2021 Inflammation contributes centrally to cardiovascular diseases, and anti-inflammatory treatments can reduce cardiovascular events. The JAK-STAT pathway is an emerging target in inflammation, mainly in rheumatoid arthritis (RA) and chronic ...
C. Baldini +4 more
semanticscholar +1 more source