Results 161 to 170 of about 28,872 (211)
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Synthesis of myo-inositol 1,3,4,5-tetraphosphate and myo-inositol 1,3-bisphosphate
Journal of the Chemical Society, Chemical Communications, 1987myo-Inositol 1,3,4,5-tetraphosphate, myo-inositol 3,4-bisphosphate, and myo-inositol 4-phosphate have been prepared via routes in which a key step is a novel, highly regioselective monoalkylation of myo-inositol orthoformate.
David C. Billington, Raymond Baker
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The enzymic determination of myo-inositol
Biochimica et Biophysica Acta, 1958An inositol dehydrogenase obtained from myo-inositol-grown Aerobacter aerogenes has been adapted for the determination of myo-inositol in microgram amounts. The other cyclitols and sugars tested do not interfere with this assay, though colchicine exerts a marked inhibitory effect.
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myo-Inositol-1,2,3,4,5,6-hexakisphosphate
Phytochemistry, 2003myo-Inositol-1,2,3,4,5,6-hexakisphosphate (Ins P(6)) was first described as an abundant form of phosphorus in plant seeds and other plant tissues and dubbed "phytic acid". Subsequently it was found to be a common constituent in eukaryotic cells, its metabolism a basic component of cellular housekeeping.
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The total synthesis of myo-inositol phosphates via myo-inositol orthoformate
Journal of the Chemical Society, Perkin Transactions 1, 1989Novel selective alkylations of myo-inositol orthoformate (4) have been used to prepare a series of protected myo-inositol derivatives, (5a–e), (7), (10), (12), and (16). These intermediates have been used in efficient total syntheses of myo-inositol 2-phosphate, (9); myo-inositol 4-phosphate, (6); myo-inositol 1,3-bisphosphate, (18); and myo-inositol 1,
David C. Billington +6 more
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myo-Inositol Metabolism in the Neonatal and Developing Rat Fed a myo-Inositol-free Diet
The Journal of Nutrition, 1976Neonatal rats of the Holtzman strain, 6 days of age, were fed a myo-inositol restricted liquid formula by gastric intubation for 10 days, after which they were fed a purified myo-inositol-free diet until they were 72 days old. No differences in weight gain were observed between myo-inositol/100 ml of formula or 150 mg myo-inositol/100 g diet.
L E, Burton +5 more
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Phosphorus, Sulfur, and Silicon and the Related Elements, 1990
Abstract The recent discovery o f the r o l e o f D-myo-inositol-1,4,5 trisphosphate Ins as the second messenger for receptor-mediated Ca2+ mobilization (1) (1,4,5)P3 has generated a great interest in the chemical preparation of myo-inositol phosphates-2 which were only available by enzymatic extraction from bovine brains (°).
Brigitte Duthu +2 more
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Abstract The recent discovery o f the r o l e o f D-myo-inositol-1,4,5 trisphosphate Ins as the second messenger for receptor-mediated Ca2+ mobilization (1) (1,4,5)P3 has generated a great interest in the chemical preparation of myo-inositol phosphates-2 which were only available by enzymatic extraction from bovine brains (°).
Brigitte Duthu +2 more
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Synthesis of some carbamates of myo-inositol
Carbohydrate Research, 1992The syntheses are described of the 1-O-carbamoyl (11), 1-O-carbamoyl-2-O-stearoyl (10), 1-O-(acetylcarbamoyl)-2-O-stearoyl (12), 1-O-(heptylcarbamoyl) (13), 2-O-(heptylcarbamoyl) (14) 1,2-di-O-(heptylcarbamoyl) (15), and 1-O-(octadecylcarbamoyl) (16) derivatives of myo-inositol. None of these compounds had significant activity against phospholipase C.
M, Brufani +7 more
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Conformational studies of myo-inositol phosphates
Carbohydrate Research, 1996The discovery of the second messenger role of myo-inositol 1,4,5-trisdihydrogenphosphate [Ins(1,4,5)P3] has triggered tremendous interest in investigating the structure, metabolism, and biological roles of inositol phosphates. Although the conformation of phytic acid [(myo-inositol hexakisdihydrogenphosphate), Ins P6] has been the subject of much study,
L G, Barrientos, P P, Murthy
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An enzymatic fluorimetric assay for myo-inositol
Analytical Biochemistry, 1984An enzymatic assay for myo-inositol (MI) is described. The method is based on the oxidation of MI by NAD+-dependent myo-inositol dehydrogenase, coupled to reoxidation of NADH with oxalacetate and malate dehydrogenase. The resultant malate is measured fluorimetrically.
L C, MacGregor, F M, Matschinsky
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myo-Inositol activity of oxidation products derived from myo-inositol
Archives of Biochemistry and Biophysics, 1962J A, JOHNSTON +3 more
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