Results 181 to 190 of about 78,749 (287)

Translational studies of chronic supplementation with a mitochondria‐targeted antioxidant to improve physical function with ageing

The Journal of Physiology, EarlyView.
Abstract figure legend Chronic oral supplementation with the mitochondria‐targeted antioxidant MitoQ (4 weeks; 250 µm) mitigates age‐related physical dysfunction in old mice, which is associated with reductions in skeletal muscle mitochondria‐specific superoxide and markers of mitochondrial reactive oxygen species (mitoROS)‐related oxidative stress and
Kevin O. Murray, Rachel A. Gioscia‐Ryan, Jaime N. Justice, Jessica R. Santos‐Parker, Nina Z. Bispham, David A. Hutton, Sanna Darvish, Jill Miyamoto‐Ditmon, Zachary S. Clayton, Michel Chonchol, Douglas R. Seals, Matthew J. Rossman   +11 more
wiley   +1 more source

The Copper Chaperone ATOX1 Exhibits Differential Protein-Protein Interactions and Contributes to Skeletal Myoblast Differentiation. [PDF]

Mol Cell Biol
Ferguson N, Zhang Y, Perez AM, Mezzell AT, Fivush JD, Shanbhag VC, Petris MJ, Vest KE.   +7 more
europepmc   +1 more source

NSAID ingestion augments training‐induced muscle hypertrophy and differentially affects muscle mRNA expression, but not strength gains, in trained men

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the impact of NSAID ingestion on resistance exercise training‐induced changes in muscle morphology, function and gene networks relative to placebo ingestion in trained males. Abstract Non‐steroidal anti‐inflammatory drugs (NSAIDs) are widely overused in sports.
Joanne E. Mallinson, Tariq Taylor, Dumitru Constantin‐Teodosiu, Despina Constantin, Martino V. Franchi, Dorothee Auer, Paul L. Greenhaff   +6 more
wiley   +1 more source

Role of Septin7 in mitochondrial dynamics and oxidative metabolism in C2C12 skeletal muscle cells. [PDF]

J Physiol
Telek A, Szabó IG, Keller-Pintér A, Gönczi M, Guti E, Szabó L, Tillmann B, Kohler ZM, Juhász L, Bai P, Póliska S, Gaál Z, Csernoch L, Fodor J.   +13 more
europepmc   +1 more source

Oxygen and glucose supplementation increases rates of linear growth and cell proliferation in growth‐restricted fetal sheep

The Journal of Physiology, EarlyView.
Abstract figure legend Effects of sustained oxygen and glucose supplementation on growth and cellular proliferation in growth‐restricted fetuses. This study evaluated whether supplemental oxygen and glucose could improve growth rates in sheep fetuses with established fetal growth restriction (FGR). Following the induction of placental insufficiency and
Mariangel Varela, Daniel B. Chrisenberry, Eliza H. Johnson, Rosa I. Luna‐Ramirez, Ayna R. Tracy, Sanya Kathuria, Weicheng Zhao, Miranda J. Anderson, Laura D. Brown, Sean W. Limesand   +9 more
wiley   +1 more source

Double-negative feedback loop between IGF2BP2 and miR-196-5p inhibits the proliferation and differentiation of primary chicken myoblasts. [PDF]

Poult Sci
Shen W, Zhang L, Lin S, Wu Y, Li L, Zhang Z.   +5 more
europepmc   +1 more source

Improved Messenger RNA Stability and Biocompatibility Through Self‐Gelatinizable Nucleic Acids

Biotechnology and Bioengineering, Volume 123, Issue 4, Page 1077-1086, April 2026.
ABSTRACT Recent advances in the chemical synthesis and modification of messenger RNA (mRNA) have generated growing interest in mRNA‐based therapeutics. However, the inherent instability of mRNA in vivo and during storage remains a major challenge, requiring the development of safe and effective delivery systems.
Takumi Tanifuji, Kosuke Kusamori, Chihiro Tanaka, Hideki Sakai, Shoko Itakura, Makiya Nishikawa   +5 more
wiley   +1 more source

Muscle RING finger-1 facilitates skeletal muscle regeneration via regulating myoblast proliferation and differentiation. [PDF]

J Transl Med
Yang M, Ji S, Gao H, Ge H, Han X, Zhan J, Zhang Q, Xu L, Li Y, Tang Z, Bu B.   +10 more
europepmc   +1 more source

Linking physical stimulation to molecular responses: The role and value of exosomes in mediating the systemic effects of Chinese Tuina

Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
(1) Tuina's mechanical forces activate cellular mechanosensors; (2) Induce multi‐tissue exosome release to mediate intercellular communication; (3) Exosomes systemically regulate muscle, nerve, immune and vascular functions; (4) Target gene knockout confirms exosomes’ specific mediating role.
Lifen Zhan, Ji Zhang, Yiping Chen, Suyu Chen, Xiantao Tai   +4 more
wiley   +1 more source

N-acetylglucosamine facilitates coordinated flow-like movement of myoblasts, forming a foundation for efficient myogenesis. [PDF]

Skelet Muscle
Satoh MS, Rancourt A, St-Pierre G, Bouchard E, Fillion M, Hagiwara K, Nakajima K, Sato S.   +7 more
europepmc   +1 more source