Results 221 to 230 of about 78,749 (287)

Distinct by Design: Unraveling the Unique Clinical and Transcriptomic Identity of Juvenile Scleromyositis Overlap Compared to Juvenile Systemic Sclerosis and Juvenile Dermatomyositis: Implications for Care and Pathogenesis

ACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective To characterize clinical and transcriptomic differences in juvenile scleromyositis overlap (jOverlap) compared to juvenile systemic sclerosis (jSSc) and juvenile dermatomyositis (JDM), focusing on autoantibody profiles, organ involvement, treatment, and peripheral blood gene expression.
Amanda D. Robinson, Clare E. Pain, Gabrielle A. Morgan, Anwesha Sanyal, Srilakshmi Chaparala, Lauren M. Pachman, Kathryn S. Torok   +6 more
wiley   +1 more source

Loss of Atoh8 Impairs Macroautophagy. [PDF]

Cells
Divvela SSK, Offei EB, Kadr H, Hausherr M, Eggers B, Rozanova S, Eisenacher M, Nguyen HD, Tuoc T, Bader V, Yang X, Zaehres H, Chen A, Nguyen HP, Winklhofer KF, Marcus K, Brand-Saberi B.   +16 more
europepmc   +1 more source

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

Advanced Functional Materials, Volume 36, Issue 23, 19 March 2026.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou, Kenny A. van Kampen, Pierpaolo Fucile, Carlos Mota, Lorenzo Moroni   +4 more
wiley   +1 more source

Addressing hurdles in cultured meat by exploring reduced myogenesis after bovine myoblast expansion. [PDF]

Commun Biol
Olenic M, Baekelandt A, Philips C, Weiland F, Thorrez L.   +4 more
europepmc   +1 more source

Geometrically Tunable Scaffold‐Free Muscle Bioconstructs for Treating Volumetric Muscle Loss

Advanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.
Volumetric muscle loss is associated with traumatic muscle resulting in permanent functional impairment. Mold‐based, scaffold‐free, high‐density muscle tissue bioconstructs are developed in customizable geometric shapes and sizes. The transplanted rectangular solid‐shaped muscle bioconstructs improved muscle force recovery and tissue regeneration in ...
Bugra Ayan, Gaoxian Chen, Ishita Jain, Sha Chen, Gladys Chiang, Caroline Hu, Renato Reyes, Beu P. Oropeza, Ngan F. Huang   +8 more
wiley   +1 more source

Picolinic acid, a tryptophan metabolite, exhibits anabolic effects in muscle cells and improves lifespan and movement in C. elegans. [PDF]

J Gerontol A Biol Sci Med Sci
Rivas D, Baltasar-Fernandez I, AlOkda A, Al Saedi A, Karasik D, Van Raamsdonk JM, Duque G.   +6 more
europepmc   +1 more source

Compression‐Tension‐Asymmetry and Stiffness Nonlinearity of Collagen‐Matrigel Composite Hydrogels

Advanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.
Self‐assembled collagen hydrogel matrices are widely used in tissue engineering applications. These matrices stiffen and contract laterally under tension due to fiber alignment and soften and collapse under compression due to fiber buckling. It is demonstrated that filler materials, such as Matrigel, linearize the mechanical behavior of collagen ...
David Böhringer, Jan Hinrichsen, Radik Gataulin, Sandra Wiedenmann, Marina Spörrer, Selda Sherifova, Paul Steinmann, Gerhard A. Holzapfel, Ben Fabry, Silvia Budday   +9 more
wiley   +1 more source

Indistinguishable mitochondrial phenotypes after exposure of healthy myoblasts to myalgic encephalomyelitis/chronic fatigue syndrome or control serum. [PDF]

PLoS One
Ryback AA, Hillier CB, Loureiro CM, Ponting CP, Dalton CF.   +4 more
europepmc   +1 more source

Giving It a Twist: One‐Step Fabrication of Aligned Biomimetic Yarn Scaffolds via Rotational Melt Electrofibrillation

Advanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.
Due to its multifunctionality, replicating the fibrillar and supramolecular architecture of Collagen I is gaining increasing priority in regenerative medicine. Using rotational Melt Electrofibrillation, we present a powerful method to accurately mimic the ultrastructure of Collagen with polycaprolactone, enabling the one‐step fabrication of three ...
Zan Lamberger, Vivien Priebe, Philipp Stahlhut, Kristina Andelovic, Girish Pattappa, Denitsa Docheva, Sven Heilig, Heike M. Hermanns, Taufiq Ahmad, Jürgen Groll, Gregor Lang, Matthias Ryma   +11 more
wiley   +1 more source

Myogenic enhancer snatching promotes adipogenic differentiation during epigenetic reprogramming mediated by lineage-specific transcription factors. [PDF]

Cell Mol Life Sci
Hu M, Xu Z, Sun J, Li L, Liu P, Zhou H, Qi X, Ren W, Liu Y, Chen S, Kuang R, Wang D, Guo Y, Sun G, Zhao S, Zhu M, Li L, Zhao Y.   +17 more
europepmc   +1 more source