Results 181 to 190 of about 16,475 (253)

Septic Shock and Prognosis in Dogs and Cats With Sepsis—Consensus Definition and Clinical Criteria

open access: yesJournal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Death from sepsis results from progressive organ dysfunction. Early recognition of increased illness severity or deterioration in clinical status enables timely interventions that can improve outcomes. We aimed to define septic shock by consensus and to use the existing literature to identify associated clinical and clinicopathologic ...
Robert Goggs   +13 more
wiley   +1 more source

A new approach to an old disease: Ageing, arrhythmogenic substrate and the role of risk‐factor modification in atrial fibrillation

open access: yesExperimental Physiology, EarlyView.
Abstract Atrial fibrillation (AF) prevalence rises sharply with age due to two independent mechanisms. Ageing produces irreversible arrhythmogenic substrate changes through progressive fibrosis, cellular senescence and mitochondrial dysfunction, while modifiable risk factors such as obesity, hypertension, sleep apnoea, diabetes and alcohol use promote ...
Udit Thakur, Jonathan M. Kalman
wiley   +1 more source

Unraveling the Mysteries of Myocardial Bridging: Left Main Anomaly Resolving With Optimal Medical Management. [PDF]

open access: yesJACC Case Rep
Gulin D   +6 more
europepmc   +1 more source

Leptin–cholesterol crosstalk in pregnancy: Mechanistic implications for placental function and cardiometabolic programming

open access: yesExperimental Physiology, EarlyView.
Abstract Pregnancy requires the coordinated maternal reorganization of lipid and endocrine pathways to sustain fetal growth and anticipate neonatal nutrition. Leptin, produced by adipose tissue and the placenta, acts as an integrative signal linking maternal energy status with trophoblast function and vascular adaptation, while cholesterol provides ...
Julio Flores   +4 more
wiley   +1 more source

Cardiac Computed Tomography for the Assessment of Myocardial Bridging: A Scoping Review of the Emerging Role of Artificial Intelligence and Machine Learning. [PDF]

open access: yesJ Cardiovasc Dev Dis
Abu Suleiman A   +9 more
europepmc   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney   +4 more
wiley   +1 more source

Association between peripheral and coronary microvascular function and the impact of myocardial bridging. [PDF]

open access: yesPhysiol Rep
Toya T   +10 more
europepmc   +1 more source

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