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Modulation of Myocardial Contraction by Peroxynitrite [PDF]

open access: yesFrontiers in Physiology, 2012
Peroxynitrite is a potent oxidant that is quickly emerging as a crucial modulator of myocardial function. This review will focus on the regulation of myocardial contraction by peroxynitrite during health and disease, with a specific emphasis on ...
Mark eKohr   +3 more
doaj   +6 more sources

Acetate suppresses myocardial contraction via the short-chain fatty acid receptor GPR43 [PDF]

open access: yesFrontiers in Physiology, 2022
The heart has high energy requirements, with an estimated 40%–60% of myocardial ATP production derived from the oxidation of fatty acids under physiological conditions.
Xuan Jiang   +10 more
doaj   +2 more sources

Speckle tracking echocardiography analyses of myocardial contraction efficiency predict response for cardiac resynchronization therapy [PDF]

open access: yesCardiovascular Ultrasound, 2018
Background In patients with left ventricular (LV) dysssynchrony, contraction that doesn’t fall into ejection period (LVEj) results in a waste of energy due to inappropriate contraction timing, which was now widely treated by cardiac resynchronization ...
Zibire Fulati   +6 more
doaj   +2 more sources

Myocardial Contraction during the Diastolic Isovolumetric Period: Analysis of Longitudinal Strain by Means of Speckle Tracking Echocardiography [PDF]

open access: yesJournal of Cardiovascular Development and Disease, 2018
Background: According to the ventricular myocardial band model, the diastolic isovolumetric period is a contraction phenomenon. Our objective was to employ speckle-tracking echocardiography (STE) to analyze myocardial deformation of the left ventricle ...
Vicente Mora   +10 more
doaj   +2 more sources

Myocardial Contractions and the Ventricular Pressure--Volume Relationship [PDF]

open access: greenarXiv, 2010
We present a reduced-order heart model with the aim of introducing a novel point of view in the interpretation of the pressure-volume loops. The novelty of the approach is based on the definition of active contraction as opposed to that of active stress.
Paola Nardinocchi   +2 more
arxiv   +3 more sources

Myocardial contraction fraction predicts mortality in the oldest old [PDF]

open access: yesInternational Journal of Cardiology: Heart & Vasculature, 2022
Background: People over the age of 85 are the world's most rapidly growing age group. Ejection fraction (EF) may be limited prognostically in this population and myocardial contraction fraction (MCF) may be more accurate.
David Leibowitz   +6 more
doaj   +2 more sources

A novel quantitative indicator of the left ventricular contraction based on volume changes of the left ventricular myocardial segments [PDF]

open access: greenarXiv, 2018
Ejection fraction (EF) is commonly measured by echocardiography, by dividing the volume ejected by the heart (stroke volume) by the volume of the filled heart (end-diastolic volume). Utilizing volume changes of left myocardial segments per a cardiac cycle, physical laws and mathematical equations specific echocardiographic data, this paper serves to ...
Mersedeh Karvandi, Saeed Ranjbar
arxiv   +3 more sources

Regulation of myocardial contraction as revealed by intracellular Ca2+ measurements using aequorin [PDF]

open access: yesJournal of Physiological Sciences
Of the ions involved in myocardial function, Ca2+ is the most important. Ca2+ is crucial to the process that allows myocardium to repeatedly contract and relax in a well-organized fashion; it is the process called excitation–contraction coupling.
Satoshi Kurihara, Norio Fukuda
doaj   +2 more sources

Prognostic impact of myocardial contraction fraction in patients undergoing transcatheter aortic valve replacement for aortic stenosis. [PDF]

open access: goldCardiovasc Diagn Ther, 2020
Romeo FJ   +8 more
europepmc   +3 more sources

Conceptualizing myocardial contractility as an emergent property that characterizes myocardial contraction

open access: goldFrontiers in Physiology
Myocardial contractility (MC) is a fundamental concept that is widely used to describe the cardiac muscles’ mechanical function, yet its definitions in textbooks and literature are vague, inconsistent, and often contradictory.
Serena Y. Kuang, Gorune Geloian
doaj   +2 more sources

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