Results 1 to 10 of about 1,127,089 (380)

Modulation of myocardial contraction by peroxynitrite. [PDF]

Front Physiol, 2012
Peroxynitrite is a potent oxidant that is quickly emerging as a crucial modulator of myocardial function. This review will focus on the regulation of myocardial contraction by peroxynitrite during health and disease, with a specific emphasis on cardiomyocyte Ca(2+) handling, proposed signaling pathways, and protein end-targets.
Kohr MJ, Roof SR, Zweier JL, Ziolo MT.
europepmc   +8 more sources

Acetate suppresses myocardial contraction via the short-chain fatty acid receptor GPR43. [PDF]

Front Physiol, 2022
The heart has high energy requirements, with an estimated 40%–60% of myocardial ATP production derived from the oxidation of fatty acids under physiological conditions.
Jiang X, Zhang Y, Zhang H, Zhang X, Yin X, Yuan F, Wang S, Tian Y.   +7 more
europepmc   +3 more sources

Conceptualizing myocardial contractility as an emergent property that characterizes myocardial contraction. [PDF]

Front Physiol
Myocardial contractility (MC) is a fundamental concept that is widely used to describe the cardiac muscles’ mechanical function, yet its definitions in textbooks and literature are vague, inconsistent, and often contradictory. In this article, we categorize these many issues into five groups and conducts a conceptual analysis to redefine MC from a ...
Kuang SY, Geloian G.
europepmc   +5 more sources

Speckle tracking echocardiography analyses of myocardial contraction efficiency predict response for cardiac resynchronization therapy. [PDF]

Cardiovasc Ultrasound, 2018
Background In patients with left ventricular (LV) dysssynchrony, contraction that doesn’t fall into ejection period (LVEj) results in a waste of energy due to inappropriate contraction timing, which was now widely treated by cardiac resynchronization ...
Fulati Z, Liu Y, Sun N, Kang Y, Su Y, Chen H, Shu X.   +6 more
europepmc   +3 more sources

Myocardial Contraction during the Diastolic Isovolumetric Period: Analysis of Longitudinal Strain by Means of Speckle Tracking Echocardiography. [PDF]

J Cardiovasc Dev Dis, 2018
Background: According to the ventricular myocardial band model, the diastolic isovolumetric period is a contraction phenomenon. Our objective was to employ speckle-tracking echocardiography (STE) to analyze myocardial deformation of the left ventricle ...
Mora V, Roldán I, Romero E, Saurí A, Romero D, Pérez-Gozalbo J, Ugalde N, Bertolín J, Rodriguez-Israel M, Delgado CP, Lowenstein JA.   +10 more
europepmc   +3 more sources

Regulation of myocardial contraction as revealed by intracellular Ca²⁺ measurements using aequorin. [PDF]

J Physiol Sci
Of the ions involved in myocardial function, Ca2+ is the most important. Ca2+ is crucial to the process that allows myocardium to repeatedly contract and relax in a well-organized fashion; it is the process called excitation–contraction coupling.
Kurihara S, Fukuda N.
europepmc   +3 more sources

A coupled mitral valve -- left ventricle model with fluid-structure interaction [PDF]

arXiv, 2017
Understanding the interaction between the valves and walls of the heart is important in assessing and subsequently treating heart dysfunction. With advancements in cardiac imaging, nonlinear mechanics and computational techniques, it is now possible to ...
Brown, André EX, Ch'ng, Quee-Lim, Currie, Michael, Grundy, Laura J, Hokanson, Jim, Javer, Avelino, Kerr, Rex, Lee, Chee Wai, Li, Chris, Li, Kezhi, Schafer, William R, Yemini, Eviatar   +11 more
core   +7 more sources

Myocardial contraction fraction predicts mortality in the oldest old. [PDF]

Int J Cardiol Heart Vasc, 2022
Background: People over the age of 85 are the world's most rapidly growing age group. Ejection fraction (EF) may be limited prognostically in this population and myocardial contraction fraction (MCF) may be more accurate.
Leibowitz D, Bishara Y, Stessman-Lande I, Hammerman-Rosenberg A, Jacobs JM, Gilon D, Stessman J.   +6 more
europepmc   +2 more sources

Coronary Artery Spasm: From Physiopathology to Diagnosis. [PDF]

Life (Basel)
Coronary artery spasm (CAS) is a reversible vasoconstriction of normal or atherosclerotic epicardial coronary arteries with a subsequent reduction in myocardial blood flow, leading to myocardial ischemia, myocardial infarction, severe arrhythmias, or ...
Savulescu-Fiedler I, Baz RO, Baz RA, Scheau C, Gegiu A.   +4 more
europepmc   +2 more sources

Methodology for Jointly Assessing Myocardial Infarct Extent and Regional Contraction in 3-D CMRI [PDF]

IEEE Transactions on Biomedical Engineering, 2012, 59 (9), pp.2650-2659, 2023
Automated extraction of quantitative parameters from Cardiac Magnetic Resonance Images (CMRI) is crucial for the management of patients with myocardial infarct. This work proposes a post-processing procedure to jointly analyze Cine and Delayed-Enhanced (DE) acquisitions in order to provide an automatic quantification of myocardial contraction and ...
arxiv   +1 more source