Results 111 to 120 of about 1,069,911 (295)

Fish Swim Bladder‐Derived ECM Hydrogels Effectively Treat Myocardial Ischemic Injury through Immunomodulation and Angiogenesis

open access: yesAdvanced Science, EarlyView.
A unique hydrogel based on extracellular matrix from fish swim bladder, which is suitable for transcatheter delivery and possesses remarkable reparative capabilities for treating heart failure, is developed. It emerges as a multi‐effect factor profoundly influencing inflammation regulation, angiogenesis, and myocardial metabolism.
Yulong Fu   +9 more
wiley   +1 more source

A Multiphysics Biventricular Cardiac Model: Simulations With a Left-Ventricular Assist Device

open access: yesFrontiers in Physiology, 2018
Computational models have become essential in predicting medical device efficacy prior to clinical studies. To investigate the performance of a left-ventricular assist device (LVAD), a fully-coupled cardiac fluid-electromechanics finite element model was
Azam Ahmad Bakir   +5 more
doaj   +1 more source

An integrated heart-torso electromechanical model for the simulation of electrophysiogical outputs accounting for myocardial deformation [PDF]

open access: yesarXiv
When generating in-silico clinical electrophysiological outputs, such as electrocardiograms (ECGs) and body surface potential maps (BSPMs), mathematical models have relied on single physics, i.e. of the cardiac electrophysiology (EP), neglecting the role of the heart motion.
arxiv  

Novel Electroactive Therapeutic Platforms for Cardiac Arrhythmia Management

open access: yesAdvanced Science, EarlyView.
Electroactive platforms offer promising applications in cardiac arrhythmia. Based on their energy sources and mechanisms, electroactive platforms are categorized into i) direct electrical stimulation, ii) self‐powered electroactive systems, iii) physical stimuli‐mediated electroactive systems, and iv) conductive systems, and their applications in ...
Juwei Yang   +4 more
wiley   +1 more source

Synchronous force and Ca2+ measurements for repeated characterization of excitation-contraction coupling in human myocardium

open access: yesCommunications Biology
Dysfunctional Ca2+ signaling affects the myocardial systole and diastole, may trigger arrhythmia and cause transcriptomic and proteomic modifications in heart failure.
Zhengwu Sun   +5 more
doaj   +1 more source

Elucidating the cellular determinants of the end-systolic pressure-volume relationship of the heart via computational modelling [PDF]

open access: yesarXiv
The left ventricular end-systolic pressure-volume relationship (ESPVr) is a key indicator of cardiac contractility. Despite its established importance, several studies suggested that the mechanical mode of contraction, such as isovolumetric or ejecting contractions, may affect the ESPVr, challenging the traditional notion of a single, consistent ...
arxiv  

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