Results 111 to 120 of about 138,711 (293)

Mechanism of inhibiting acetyl CoA carboxylase 2 to improve cardiac dysfunction in septic mice

陆军军医大学学报
Objective To observe the ameliorative effect of inhibiting acetyl-CoA carboxylase 2(ACC2) on cardiac dysfunction in septic mice and investigate its underlying mechanism.
DU Yunxia, DU Yunxia, SHE Han, SHE Han, WU Yinyu   +4 more
doaj   +1 more source

Contratura isquêmica do miocárdio: estudo experimental em ratos

Brazilian Journal of Cardiovascular Surgery, 1997
A contratura isquêmica do miocárdio (CIM) tem sido muito utilizada na investigação da fisiopatologia da isquemia global do coração. Este trabalho descreve um modelo experimental adequado ao estudo da CIM, em ratos.
Eduardo Tiveron VELUDO, Alexandre Luiz ARANHA, Alexandre PACCHIONI, Gustavo Ribeiro de OLIVEIRA, Albert Amin SADER, Yvone Avalloni de Moraes V. A. VICENTE, Walter V. A. VICENTE   +6 more
doaj   +1 more source

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

Advanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo, Dong‐Sung Won, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Chan Ho Moon, Ji Won Kim, Yubeen Park, Minho Kang, Dong Yun Lee, Donghyun Lim, Kisuk Yang, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Seokbeom Kim, Jun‐Kyu Park, Jung‐Hoon Park, Hyun‐Do Jung   +19 more
wiley   +1 more source

Soft and Adhesive Cardiac Patch for Electrophysiological and Contraction Measurement

Advanced Science, EarlyView.
This study developed an epicardial electronic patch with a modulus similar to that of the heart (approximately 65kPa), which can collect stable electrocardiogram signals and myocardial contractility on the surface of a dynamically beating heart. This is attributed to the hydrogen bond interaction formed between the amino and catechol groups in the ...
Wuliang Chen, Xinyu Shen, Hanning Liu, Lamei Du, Caicai Jiao, Longfei Li, Qian Wang, Qiuting Zhang, Lixue Tang, Liang Hu, Yubo Fan   +10 more
wiley   +1 more source

Coronary Artery Spasm: From Physiopathology to Diagnosis

Life
Coronary artery spasm (CAS) is a reversible vasoconstriction of normal or atherosclerotic epicardial coronary arteries with a subsequent reduction in myocardial blood flow, leading to myocardial ischemia, myocardial infarction, severe arrhythmias, or ...
Ilinca Savulescu-Fiedler, Radu Octavian Baz, Radu Andrei Baz, Cristian Scheau, Andrei Gegiu   +4 more
doaj   +1 more source

Quantification of Myocardial Contraction Fraction with Three-Dimensional Automated, Machine-Learning-Based Left-Heart-Chamber Metrics: Diagnostic Utility in Hypertrophic Phenotypes and Normal Ejection Fraction. [PDF]

J Clin Med, 2023
Barbieri A, Imberti JF, Bartolomei M, Bonini N, Laus V, Torlai Triglia L, Chiusolo S, Stuani M, Mari C, Muto F, Righelli I, Gerra L, Malaguti M, Mei DA, Vitolo M, Boriani G.   +15 more
europepmc   +1 more source

A Correlative SICM‐OPM Platform for Surface and Volumetric Imaging in Live Cells

Advanced Science, EarlyView.
A multifunctional correlative imaging platform integrating Scanning Ion Conductance Microscopy (SICM) with Oblique Plane Microscopy (OPM) enables simultaneous surface topography, mechanical mapping, and 3D volumetric fluorescence imaging in live cells.
Wenzhi Hong, Ziwei Zhang, Ao Li, Ting Sun, Yunzhao Wu, Devkee M. Vadukul, Dylan Jones, Bing Li, Fengjie Liu, Francesco A. Aprile, Yuri Korchev, Julia Gorelik, David Klenerman, Andrew Shevchuk   +13 more
wiley   +1 more source

Myocardial Contraction Fraction is Superior to Ejection Fraction in Predicting Functional Capacity in Patients with Heart Failure with Reduced Ejection Fraction. [PDF]

J Saudi Heart Assoc, 2022
Abdellatif YA, Addow HA, Elias RR.
europepmc   +1 more source

Investigating the protective role of the natural hormone Melatonin, in reducing drug-induced cardiotoxicity in the therapy of chronic diseases [PDF]

, 2019
Heart failure (HF) is a highly complex disorder and a major end-point of cardiovascular diseases (CVD). The pathogenesis of HF is mostly unresolved but involves interplay between cardiac structural and electrical remodelling, metabolic alterations, cell ...
Kasi Ganeshan, T., Kasi Ganeshan, T.
core  

Gel‐Amin for Improving Extracellular Recordings of Cardiomyocytes in a 3D Microphysiological System

Advanced Electronic Materials, EarlyView.
This work combines a conductive collagen‐based hydrogel with a laser‐cut and assembly technique to fabricate microphysiological systems that improve extracellular recordings of cardiomyocytes in 3D on microelectrode arrays. The inclusion of choline acrylate into GelMA imparts a higher electrical conductivity and improves the signal‐to‐noise ratio of on‐
Dominic Pizzarella, Katelyn Neuman, Nolan Burson, Abigail N. Koppes, Ryan A. Koppes   +4 more
wiley   +1 more source