Results 21 to 30 of about 1,069,911 (295)

Lipofundin® MCT/LCT 20% increase left ventricular systolic pressure in an rat heart model via increase of intracellular calcium level [PDF]

open access: yesKorean Journal of Anesthesiology, 2016
BackgroundLipid emulsions have been used to treat various drug toxicities and for total parenteral nutrition therapy. Their usefulness has also been confirmed in patients with local anesthetic-induced cardiac toxicity.
Jiyoung Park   +8 more
doaj   +1 more source

Intravenous Transplantation of an Ischemic-specific Peptide-TPP-mitochondrial Compound Alleviates Myocardial Ischemic Reperfusion Injury

open access: yesACS Nano, 2023
It is known that mitochondrial dysfunction is a critical factor involved in myocardial ischemia–reperfusion injury. Mitochondrial transplantation has been suggested as an effective therapeutic strategy to protect against myocardial ischemia–reperfusion ...
Xiaolei Sun   +12 more
semanticscholar   +1 more source

Stunned myocardium [PDF]

open access: yesVojnosanitetski Pregled, 2005
Background. Stunned myocardium is a state of delayed recovery of regional contractility after a transient period of ischemia followed by reperfusion. Case report.
Ristić Anđelka   +3 more
doaj   +1 more source

The role of myocardial mechanical and QTc dispersion in detecting significant coronary artery disease

open access: yesJournal of Medicine in Scientific Research, 2022
Background Prolonged myocardial contraction and QT interval duration may be found in ischemic viable myocardium, yet it is unclear if noninvasive examination of regional nonhomogeneous myocardial mechanics and QT duration may detect patients with ...
Mohamed R Badran
doaj   +1 more source

A comparative study of embedded and anesthetized zebrafish in vivo on myocardiac calcium oscillation and heart muscle contraction

open access: yesFrontiers in Pharmacology, 2010
The zebrafish (Danio rerio) has been used as a model for studying vertebrate development in the cardiovascular system. In order to monitor heart contraction and cytosolic calcium oscillations, fish were either embedded in methylcellulose or anesthetized
Brian eMuntean   +6 more
doaj   +1 more source

SERCA2a ameliorates cardiomyocyte T-tubule remodeling via the calpain/JPH2 pathway to improve cardiac function in myocardial ischemia/reperfusion mice

open access: yesScientific Reports, 2021
Transverse-tubules (T-tubules) play pivotal roles in Ca2+-induced, Ca2+ release and excitation–contraction coupling in cardiomyocytes. The purpose of this study was to uncover mechanisms where sarco/endoplasmic reticulum Ca2+ ATPase (SERCA2a) improved ...
Shuai Wang   +9 more
doaj   +1 more source

Vigorous Vascular Contraction Mimicking Myocardial Bridge Resulting from Digoxin Treatment in an Elderly Patient

open access: yesInternational Journal of Gerontology, 2016
Myocardial bridge is defined as the intramyocardial course of a segment of a coronary artery. Digoxin increases the force of myocardial contraction, which augments the compression of the vessel.
Wai-Kin Wong, Po-Jung Yuan
doaj   +1 more source

A comprehensive and biophysically detailed computational model of the whole human heart electromechanics [PDF]

open access: yes, 2022
While ventricular electromechanics is extensively studied, four-chamber heart models have only been addressed recently; most of these works however neglect atrial contraction. Indeed, as atria are characterized by a complex physiology influenced by the ventricular function, developing computational models able to capture the physiological atrial ...
arxiv   +1 more source

Imaging the dynamics of cardiac fiber orientation in vivo using 3D Ultrasound Backscatter Tensor Imaging [PDF]

open access: yesScientific Reports, 2017, 7 (1), pp.830, 2023
The assessment of myocardial fiber disarray is of major interest for the study of the progression of myocardial disease. However, time-resolved imaging of the myocardial structure remains unavailable in clinical practice. In this study, we introduce 3D Backscatter Tensor Imaging (3D-BTI), an entirely novel ultrasound-based imaging technique that can ...
arxiv   +1 more source

The impact of myocardial compressibility on organ-level simulations of the normal and infarcted heart

open access: yesScientific Reports, 2021
Myocardial infarction (MI) rapidly impairs cardiac contractile function and instigates maladaptive remodeling leading to heart failure. Patient-specific models are a maturing technology for developing and determining therapeutic modalities for MI that ...
Hao Liu   +10 more
doaj   +1 more source

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