Background: The post-myocardial infarction (MI) scar interrupts electrical impulse propagation and delays regional contraction, which contributes to ventricular dysfunction. We investigated the potential of an injectable conductive biomaterial to restore
Zhi Cui+8 more
semanticscholar +1 more source
Assessment of Left Atrial Deformation and Function by 2-Dimensional Speckle Tracking Echocardiography in Healthy Dogs and Dogs With Myxomatous Mitral Valve Disease [PDF]
open7noBackground: The assessment of left atrial (LA) function by 2-dimensional speckle tracking echocardiography (STE) holds important clinical implications in human medicine. Few similar data are available in dogs.
Baron Toaldo, M.+6 more
core +2 more sources
A pseudo active kinematic constraint for a biological living soft tissue: an effect of the collagen network [PDF]
Recent studies in mammalian hearts show that left ventricular wall thickening is an important mechanism for systolic ejection and that during contraction the cardiac muscle develops significant stresses in the muscular cross-fiber direction. We suggested
Bourdarias, Christian+2 more
core +4 more sources
Transthoracic super-resolution ultrasound localisation microscopy of myocardial vasculature in patients [PDF]
Micro-vascular flow in the myocardium is of significant importance clinically but remains poorly understood. Up to 25% of patients with symptoms of coronary heart diseases have no obstructive coronary arteries and have suspected microvascular diseases. However, such microvasculature is difficult to image in vivo with existing modalities due to the lack
arxiv +1 more source
Advances in computational modelling for personalised medicine after myocardial infarction [PDF]
Myocardial infarction (MI) is a leading cause of premature morbidity and mortality worldwide. Determining which patients will experience heart failure and sudden cardiac death after an acute MI is notoriously difficult for clinicians. The extent of heart
Berry, Colin+4 more
core +1 more source
Exercise training corrects control of spontaneous calcium waves in hearts from myocardial infarction heart failure rats [PDF]
Impaired cardiac control of intracellular diastolic Ca<sup>2+</sup> gives rise to arrhythmias. Whereas exercise training corrects abnormal cyclic Ca<sup>2+</sup> handling in heart failure, the effect on diastolic Ca<sup>2 ...
American Heart Association+23 more
core +1 more source
Recent Developments in Cardiac Contractility Modulation for Heart Failure [PDF]
None.
Joshua R. Hirsch, MD, Hamid Afshar, MD
doaj +1 more source
Myocardial ischemic effects on cardiac electro-mechanical activity [PDF]
In this work, we investigated the effect of varying strength of Hyperkalemia and Hypoxia, in human cardiac tissue with a local ischemic subregion, on the electrical and mechanical activity of healthy and ischemic zones of the cardiac muscle. The Monodomain model in a deforming domain is taken with the addition of mechanical feedback and stretch ...
arxiv
Gene therapy with Angiotensin-(1-9) preserves left ventricular systolic function after myocardial infarction [PDF]
BACKGROUND: Angiotensin-(1-9) [Ang-(1-9)] is a novel peptide of the counter-regulatory axis of the renin angiotensin system previously demonstrated to have therapeutic potential in hypertensive cardiomyopathy when administered via osmotic minipump in ...
Fattah, Caroline+12 more
core +2 more sources
Background: Recent and emerging evidences show that glucose ingestion causes prolonged Q-T interval and can trigger arrhythmia. Objective: The objective of this study is to examine the effects of administration of glucose solutions on the heart rate ...
B I Waziri, A Shahzad
doaj +1 more source