Results 61 to 70 of about 299,715 (311)

Tumor Necrosis Factor-α Contributes to Ischemia- and Reperfusion-Induced Endothelial Activation in Isolated Hearts [PDF]

, 1999
During myocardial reperfusion, polymorphonuclear neutrophil (PMN) adhesion involving the intercellular adhesion molecule-1 (ICAM-1) may lead to aggravation and prolongation of reperfusion injury.
Kelly, Ralph A., Stefan Zahler, Habazettl, Helmut, Goedecke, Axel, Becker, Bernhard F., Dieter A. Wolf, Christian Kupatt, Helmut Habazettl, Boekstegers, Peter, Bernhard F. Becker, Kupatt, Christian, Peter Boekstegers, Zahler, Stefan, Wolf, Dieter A., Ralph A. Kelly, Axel Goedecke   +15 more
core   +1 more source

Microfabricated Anisotropic Myobundles for the Scalable Production of Cardiac Tissue Grafts

Advanced Functional Materials, EarlyView.
Controlling the anisotropy of cardiac tissue remains an outstanding challenge in the field of cardiac tissue engineering. Here, we introduce an approach to generate anisotropic cardiac myobundles using cell‐adhesive, synthetic, electrospun fibers and stem cell‐derived cardiac fibroblasts.
Maggie E. Jewett, Javiera Jilberto, Margaret E. Stanley, David O. Ntim, Siddhi M. Bhirud, Avianna T. Schroeder, Gonzola X. Anyosa Galvez, Jingyi Xia, Samuel J. DePalma, Emmanouil Agrafiotis, Susan S. Xi, Amanda S. Bluem, Courtney M. Lestock, Adam S. Helms, David A. Nordsletten, Brendon M. Baker   +15 more
wiley   +1 more source

Systematic Review and Meta-Analysis of SERPINE1 4G/5G Insertion/Deletion Variant With Circulating Lipid Levels

Frontiers in Cardiovascular Medicine, 2022
BackgroundRecent studies have shown that the 4G/5G insertion/deletion variant of SERPINE1 (rs1799889) is closely linked to coronary artery disease (CAD).
Zhi Luo, Yang Liu, Hang Li, Yawen Zhou, Yuanyuan Peng, Xuan Lin, Ying Fang, Jing Wan, Jing Wan, Baozhu Wei, Baozhu Wei   +10 more
doaj   +1 more source

Effective components screening and anti-myocardial infarction mechanism study of the Chinese medicine NSLF6 based on "system to system" mode

, 2012
Background Shuanglong formula (SLF), a Chinese medicine composed of panax ginseng and salvia miltiorrhiza exhibited significant effect in the treatment of myocardial infarction (MI) in clinical. Because of the complex nature and lack of stringent quality
Yuan-Yuan Xie, Chen, Xi, Lv Shu-Feng, Liang, Q-L, Xu, Qing-Bo, Qing-Bo Xu, Liang Qiong-Lin, Cheng, Yi-Jun, Zhang, Q-L, Rong Gao, Xu, Q-B, Yi-Ming Wang, Zhang, Rong-Li, Xue Li, Gao, Rong, Lv, Shu-Feng, Zhang Rong-Li, Shu-Feng Lv, Xu Qing-Bo, Xi Chen, Xue-Mei Fan, Liang, Xiao-Ping, Liang Xiao-Ping, Jun Wu, Wu Jun, Xie Yuan-Yuan, Luo Guo-An, Zhang, Qing-Li, Zhang Hong-Yang, Xiao-Ping Liang, Gao, R, Luo, Guo-An, Xie, Yuan-Yuan, Zhang, Hong-Yang, Cheng, Y-J, Fan Xue-Mei, Zhang Qing-Li, Liang, Qiong-Lin, Xiao, Q-Z, Zhang, H-Y, Xiao, Qing-Zhong, Zhang, R-L, Yi-Jun Cheng, Chen, X, Wu, Jun, Xie, Y-Y, Luo, G-A, Qing-Li Zhang, Qiong-Lin Liang, Wang, Yi-Ming, Qing-Zhong Xiao, Lv, S-F, Gao Rong, Li Xue, Wang, Y-M, Wu, J, Fan, Xue-Mei, Cheng Yi-Jun, Hong-Yang Zhang, Wang Yi-Ming, Fan, X-M, Li, Xue, Liang, X-P, Guo-An Luo, Chen Xi, Xiao Qing-Zhong, Li, X, Rong-Li Zhang   +67 more
core   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Reduction of myocardial infarction by calpain inhibitors A-705239 and A-705253 in isolated perfused rabbit hearts [PDF]

, 2004
Two novel calpain inhibitors (A-705239 and A-705253) were studied in isolated perfused rabbit hearts subjected to 60-min occlusion of the ramus interventricularis of the left coronary artery (below the origin of the first diagonal branch), followed by ...
Speth, Maria, Deibele, Karin, Neuhof, Heinz, Lubisch, Wilfried, Möller, Achim, Neuhof, Christiane, Fabiunke, Verena, Fritz, Hans, Tillmanns, Harald   +8 more
core   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Interface‐Engineered Binary Framework Composites: Advancing Porous Materials for Precision Medicine

Advanced Materials Interfaces, EarlyView.
Binary framework composites integrate two complementary porous architectures into a unified platform, enabling multifunctional design, enhanced structural tunability, and improved physicochemical performance. By combining high surface area, ordered porosity, interfacial synergy, and versatile functionalization, these hybrid materials offer new ...
Navid Rabiee, Mohammad Rabiee, Mohammad Akrami‐Hasan‐Kohal, Sidi A. Bencherif   +3 more
wiley   +1 more source

Diagnostic performance of multi-branch coronary angiography-based index of microcirculatory resistance: a novel approach

Frontiers in Medicine
BackgroundWire-based index of microcirculatory resistance (IMR) utilizing pressure wires and thermodilution techniques for the assessment of coronary microcirculatory function, presents challenges for clinical routine use due to its complexity, time ...
Yongzhen Fan, Yongzhen Fan, Shuang Wang, Xinyong Cai, Xiaorong Hu, Xiaorong Hu, Jun Ma, Hongzhi Lan, Zhibing Lu, Zhibing Lu   +9 more
doaj   +1 more source

Calibration of myocardial T2 and T1 against iron concentration. [PDF]

, 2014
BACKGROUND: The assessment of myocardial iron using T2* cardiovascular magnetic resonance (CMR) has been validated and calibrated, and is in clinical use.
Timothy G St. Pierre, St Pierre, TG, Firmin, DN, Forni, G, Mary N Sheppard, Fleming, A, Gualtiero Catani, He, T, Gianluca Forni, Taigang He, House, M, Sofia V de Noronha, Carpenter, JP, Black, G, Walker, J, Sheppard, MN, Kirk, P, Baksi, AJ, John C Wood, Porter, JB, John B Porter, Mike House, Walker, JM, Fucharoen, S, Wood, JC, Suthat Fucharoen, A John Baksi, Pennell, DJ, Adam Fleming, Greg Black, Anderson, LJ, Baksi, A, Dudley J Pennell, Paul Kirk, Lisa J Anderson, David N Firmin, John-Paul Carpenter, J Malcolm Walker, Gildo Matta, Michael Roughton, Roughton, M, de Noronha, SV, Matta, G, Catani, G   +43 more
core   +1 more source