Results 171 to 180 of about 107,803 (293)

Cardiac disease in systemic sclerosis: Integrating pathobiology with clinical management

Rheumatology &Autoimmunity, EarlyView.
Abstract Systemic sclerosis (SSc) is a complex autoimmune disorder in which cardiovascular involvement remains a major determinant of morbidity and mortality. Cardiac injury in SSc results from the interplay of microvascular dysfunction, immune‐mediated inflammation, and progressive interstitial and replacement fibrosis, leading to myocardial disease ...
Henry Sutanto, Betty Rachma, Yuliasih
wiley   +1 more source

Modified mRNA-Based Therapeutic Strategies for Myocardial Ischemia-Reperfusion Injury. [PDF]

Int J Mol Sci
Cai T, Yang XQ.
europepmc   +1 more source

New Advances of Degradable Magnesium‐Based Metal Biomaterials in the Field of Orthopedics

Rare Metals, EarlyView.
ABSTRACT Based on their outstanding biomechanical properties and superior osteogenic activity, magnesium (Mg) and its alloys have been extensively investigated for their biocompatibility and therapeutic efficacy in treating fractures and bone defects.
Jia‐Nan Yu, Shao‐Sheng Jia, Rong‐Bang Sun, Tong Zhang, Ling‐Chuang Bai, Di Mei, Shi‐Jie Zhu, Lan Chen, Shao‐Kang Guan   +8 more
wiley   +1 more source

Purine Nucleotide Precursors in Preventing Myocardial Ischemia-Reperfusion Injury. [PDF]

Int J Mol Sci
Musial PT, Badtke PA, Zabielska-Kaczorowska MA.   +2 more
europepmc   +1 more source

A new strategy of construction of porcine myocardial infarction model for preclinical research

VIEW, EarlyView.
This study proposes a strategy based on the anatomical classification of the porcine left coronary artery (LCA) to establish a stable and reproducible myocardial infarction (MI) model for preclinical research. A combination of LCA classification into nine types via angiography, screening of candidate subtypes, and application of a novel embolic ...
Shixing Huang, Haonan Zhang, Jie Jiang, Bei Qian, Yiming Zhong, Xinming Wang, Kai Wang, Jianglin Wang, Xuan Lu, Qiang Zhao, Xiaofeng Ye   +10 more
wiley   +1 more source

Screening and verification of drugs targeting myocardial ischemia-reperfusion injury. [PDF]

Medicine (Baltimore)
Liu Q, Tian Z, Mi S, Liang Z, Hang B.
europepmc   +1 more source

Time of day of cardiac surgery and postoperative outcomes in the UK: a secondary analysis of linked national datasets

Anaesthesia, EarlyView.
Summary Introduction Uncertainty remains regarding whether the time of day that cardiac surgery is performed affects postoperative outcomes or if the observed variation can be explained by patient or surgical factors. Methods A secondary analysis of prospectively collected data was conducted to examine the association between time of cardiac surgery ...
Gareth Kitchen, Karen Thomas, Tim Felton, Hannah Durrington, John Blaikley, Stuart W. Grant, David Harrison, Peter McGuigan, Kathryn Rowan, Anthony Wilson, Danny McAuley, Paul Dark   +11 more
wiley   +1 more source

Integrating Dialysis in Ex Situ Machine Perfusion: A Systematic Review and Meta‐Analysis of Outcomes

Artificial Organs, EarlyView.
Dialysis‐enhanced EVMP effectively maintains biochemical homeostasis, potentially mitigating metabolic stress and extending perfusion duration. Functional outcomes varied depending on the organ type, with the most pronounced benefits observed in cardiac perfusion.
Yomna E. Dean, Sean Frisbie, James Gaston, Diwakar Phuyal, Bahareh Tabatabaei, Florian Huwyler, Matthias Pfister, Jonas Binz, Antonio Rampazzo, Gábor Szabó, Mark W. Tibbit, Pierre‐Alain Clavien, Bahar Bassiri Gharb   +12 more
wiley   +1 more source

Tilianin Attenuates Myocardial Ischemia-Reperfusion Injury by Targeting RIP3-Mediated Necroptosis. [PDF]

Pharmaceuticals (Basel)
Zheng R, Yang J, Wang X, Jin Y, Wang Y, Su W, Chen N, Chu S, Xing J, Xu M.   +9 more
europepmc   +1 more source

Optimizing Donor Kidneys During Normothermic Machine Perfusion With Sevoflurane: Design of a Research Model

Artificial Organs, EarlyView.
A stable kidney normothermic machine perfusion model with sevoflurane delivery via a vaporizer was established, enabling mechanistic and therapeutic studies of ischemia–reperfusion injury. ABSTRACT Normothermic machine perfusion (NMP) of donor kidneys provides an opportunity not only for organ preservation but also for therapeutic intervention to ...
Philip N. Günkel, Shuqi Yang, Rozemarijn S. Tuinhout, Sebastiaan J. Luttik, Roland F. Hoffmann, Petra J. Ottens, Damien Richard, Matthieu Jabaudon, Michel M. R. F. Struys, Henri G. D. Leuvenink, Gertrude J. Nieuwenhuijs‐Moeke   +10 more
wiley   +1 more source