Results 261 to 270 of about 106,495 (306)

Lysosomal homeostasis regulates myocardial ischemia-reperfusion injury through autophagy pathway. [PDF]

Sci Rep
Li Y, Liu Y, Wu H, Zhang S, Liu D, Huang X, Zhou G, Zhang D, Yang X, Zhou T, Xiong Y.   +10 more
europepmc   +1 more source

Advanced Nanomaterial Platforms for Targeted Therapy of Myocardial Ischemia-Reperfusion Injury. [PDF]

Research (Wash D C)
Wang H, Li L, Luo L, Cheng Y, Zhou F, Zhao S, Li Y, Yang Y, Zhou Q, Niu H, He J, Zhang C, Guo J, Tang L, Xu J.   +14 more
europepmc   +1 more source

Identification of Pyroptosis-Related Genes and Immune Landscape in Myocardial Ischemia-Reperfusion Injury. [PDF]

Biomedicines
Zhu Y, Zhu H, Zhou J, Wu J, Hu X, Li C, Cai H, Lu Z.   +7 more
europepmc   +1 more source

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Lymphocyte Communication in Myocardial Ischemia/Reperfusion Injury

Antioxidants and Redox Signaling, 2017
Significance: Myocardial ischemia/reperfusion (I/R) is an important complication of reperfusion therapy for myocardial infarction (MI). It is a complex process involving metabolic and immunological factors. To date, no effective treatment has been identified.
Emanuele Andreano, Ioakim Spyridopoulos   +1 more
exaly   +4 more sources

Purinergic signaling in myocardial ischemia–reperfusion injury

Purinergic Signalling, 2022
Purines and their derivatives, extensively distributed in the body, act as a class of extracellular signaling molecules via a rich array of receptors, also known as purinoceptors (P1, P2X, and P2Y). They mediate multiple intracellular signal transduction pathways and participate in various physiological and pathological cell behaviors.
Yi, Zhuang, Mei-Ling, Yu, Sheng-Feng, Lu
openaire   +2 more sources

Peroxynitrite in Myocardial Ischemia-Reperfusion Injury

Heart Failure Reviews, 2002
Peroxynitrite is a highly reactive oxidant which is produced during reperfusion of the ischemic heart. The role that this molecule plays in reperfusion injury has been controversial. Many investigations have demonstrated toxic effects of peroxynitrite, whereas others have found it to be protective during reperfusion.
Manoj M, Lalu, Wenjie, Wang, Richard, Schulz   +2 more
openaire   +2 more sources

The Role of P53 in Myocardial Ischemia-Reperfusion Injury

Cardiovascular Drugs and Therapy, 2023
P53 is one of the key tumor suppressors. In normal cells, p53 is maintained at low levels by the ubiquitination of the ubiquitinated ligase MDM2. In contrast, under stress conditions such as DNA damage and ischemia, the interaction between p53 and MDM2 is blocked and activated by phosphorylation and acetylation, thereby mediating the trans-activation ...
Xi-zi Zhu, Zhen Qiu, Shao-qing Lei, Yan Leng, Wen-yuan Li, Zhong-yuan Xia   +5 more
openaire   +2 more sources

Connexin43 and Myocardial Ischemia-Reperfusion Injury

Cardiovascular & Hematological Disorders-Drug Targets, 2018
Recently, the treatment and prevention of ischemic cardiomyopathy is one of the emerging research topics in the cardiovascular field. Gap junction is the basic structure of cardiac electrophysiology. Connexin is the basic unit of gap junctions. Connexin43(CX43) is the most abundant member of Cx family in the heart, the normal expression of Cx43 is ...
Lingyun, Zu, Ningxin, Wen, Changjie, Liu, Mingming, Zhao, Lemin, Zheng   +4 more
openaire   +2 more sources

Zinc and myocardial ischemia/reperfusion injury

BioMetals, 2013
As an important trace element, zinc is required for the normal cellular structure and function, and impairment of zinc homeostasis is associated with a variety of health problems including cardiovascular disease. Zinc homeostasis is regulated through zinc transporters, zinc binding molecules, and zinc sensors.
Zhelong, Xu, Juan, Zhou
openaire   +2 more sources