Results 91 to 100 of about 217,798 (269)

Dynamic detection and reversal of myocardial ischemia using an artificially intelligent bioelectronic medicine

, 2022
Patrick D. Ganzer, Masoud S. Loeian, Steve Roof, Bunyen Teng, Luan Lin, David A. Friedenberg, Ian W. Baumgart, Eric Meyers, Keum San Chun, Adam Rich, Allison Tsao, William W. Muir, Doug J Weber, Robert L. Hamlin   +13 more
openalex   +1 more source

Loganin alleviates myocardial ischemia–reperfusion injury through GLP‐1R / NLRP3 ‐mediated pyroptosis pathway [PDF]

, 2023
LI Wen-fan, Pei Fan, Xiaobo Wang, Haifeng Tang   +3 more
openalex   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Corrigendum: C1q/TNF-Related Protein 9 Attenuates Atherosclerosis by Inhibiting Hyperglycemia-Induced Endothelial Cell Senescence Through the AMPKα/KLF4 Signaling Pathway

Frontiers in Pharmacology, 2021
Gang Wang, Gang Wang, Baihe Han, Baihe Han, Ruoxi Zhang, Qi Liu, Qi Liu, Xuedong Wang, Xuedong Wang, Xingtao Huang, Xingtao Huang, Dandan Liu, Dandan Liu, Weishen Qiao, Weishen Qiao, Mengyue Yang, Mengyue Yang, Xing Luo, Xing Luo, Jingbo Hou, Jingbo Hou, Bo Yu, Bo Yu   +22 more
doaj   +1 more source

Cold-driven biphasic vascular healing in elderly patients: 4D optical coherence tomography stratification of major adverse cardiovascular event risk based on age-environment interactions

Frontiers in Cardiovascular Medicine
BackgroundBiological aging and prolonged cold exposure each impair vascular healing after implantation of a drug-eluting stent. However, their combined effect—particularly in older adults living in cold climates—remains poorly understood.ObjectiveTo ...
Linxing Feng, Linxing Feng, Huaxing Liu, Huaxing Liu, Zhiyong Li, Zhiyong Li, Lei Xing, Lei Xing   +7 more
doaj   +1 more source

Naringin attenuates acute myocardial ischemia-reperfusion injury via miR- 126/GSK-3β/β-catenin signaling pathway [PDF]

, 2022
Xiuhui Guo, Qinghong Ji, Mei Wu, Weihong Ma   +3 more
openalex   +1 more source

Programmable Pentamolecular Cross‐Scale Imaging Reveals the Multiplicative Synergistic Effect of High‐Fat / High‐Salt Diet on Atherosclerosis

Advanced Science, EarlyView.
This study demonstrates multifactorial lifestyle impacts on the pathogenesis and progression of cardiovascular diseases by a nanofluorescence sensor array for detecting four redox species and protein phosphorylation levels. Through cross‐scale fluorescence imaging of rats with different diets, we revealed that compared with single dietary interventions,
Jin Li, Na Zhao, Mengmeng Lu, Ruize Zhao, Wei Zhang, Ping Li, Yue Tang, Wen Zhang, Hui Wang, Bo Tang   +9 more
wiley   +1 more source

Mechanisms of sorafenib-induced cardiotoxicity: ER stress induces upregulation of ATF3, leading to downregulation of NDUFS1 expression and mitochondrial dysfunction

Frontiers in Pharmacology
BackgroundSorafenib, a widely used tyrosine kinase inhibitor (TKI), has been associated with cardiotoxic effects; however, the precise molecular basis of this toxicity remains incompletely characterized.
Ming Yan, Ming Yan, Ming Yan, Cheng Peng, Cheng Peng, Xueyan Lang, Xueyan Lang, Yilan Li, Yilan Li, Yao Zhang, Yao Zhang   +10 more
doaj   +1 more source

[Retracted] Effects of Aspirin on Myocardial Ischemia‐Reperfusion Injury in Rats through STAT3 Signaling Pathway [PDF]

, 2021
Zhenjun Wu, Xuewen Li, Xiuyue Li, Lihua Yu   +3 more
openalex   +1 more source

Precision‐Engineered Silver Single‐Atom Carbon Dot Nanozymes for Theranostic Management of Acute Kidney Injury

Advanced Science, EarlyView.
Mitochondria‐targeted silver single‐atom carbon dot (T‐AgSA‐CDs) nanozymes enable dual SOD/GPx‐like ROS scavenging, real‐time imaging, and therapeutic effects for acute kidney injury (AKI). Atomically dispersed Ag sites synergize with carbon dots to restore renal redox hemostasis, protect mitochondrial function, mitigate inflammation, facilitate post ...
Tianle Tang, Jun Zhang, Yan Wang, Guoping Chen, Kehui Yuan, Yuan He, Chenchen Li, Sumaira Hanif, Yang Yang, Yanli Wang, Pir Muhammad   +10 more
wiley   +1 more source