Results 251 to 260 of about 105,760 (306)

Proteolytic remodelling of the extracellular matrix by pericytes

open access: yesThe FEBS Journal, Volume 293, Issue 13, Page 3899-3953, July 2026.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard   +4 more
wiley   +1 more source

Oxypaeoniflorin Ameliorates Titanium Particle‐Stimulated Osteolysis by Targeting Nrf2 to Reprogram Mitochondrial Homeostasis in Osteoclasts

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT Wear debris surrounding implants plays a crucial role in the development of periprosthetic osteolysis (PPO) by inducing the aggregation of osteoclasts around the prosthesis. Oxypaeoniflorin (OPF), a derivative of Paeoniflorin, is primarily sourced from the root of the traditional Chinese medicine peony and possesses anti‐inflammatory and ...
Feng Zhu   +10 more
wiley   +1 more source

Valsartan Reduces Myocardial Ischemia–Reperfusion Injury by Inhibiting Ferritinophagy‐Mediated Ferroptosis

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT Revascularisation is the key therapeutic strategy for acute myocardial infarction (AMI). However, the opening of the ‘culprit artery’ is accompanied by myocardial ischemia–reperfusion injury (IRI), partially offsetting the benefits of revascularisation. At present, effective methods to alleviate myocardial IRI are lacking.
Xumin Wang   +8 more
wiley   +1 more source

Macrophage-enriched HMOX1 is an ischemia-reperfusion-responsive marker in the heart. [PDF]

open access: yesJ Thorac Dis
Bi X   +10 more
europepmc   +1 more source

Inflammatory Stewardship—A Perspective for Active Management of Acute Inflammation

open access: yesThe FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Inflammatory stewardship frames inflammation as a manageable clinical domain requiring explicit strategy, governance, and feedback. It aligns diagnostics, risk stratification, biomarker interpretation, and immunomodulatory decisions across perioperative and critical‐care teams.
Lennart Finn Herrlich   +2 more
wiley   +1 more source

Remote Ischemic Conditioning as an Adjunct to Primary Percutaneous Coronary Intervention in ST-Elevation Myocardial Infarction: A Systematic Review and Meta-Analysis. [PDF]

open access: yesCureus
Khormi MA   +11 more
europepmc   +1 more source

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