Results 241 to 250 of about 282,175 (385)

FAM20C Modulates Neuronal Differentiation in Hypoxic–Ischemic Brain Damage via KAP1 Phosphorylation and LINE1 RNA m6A‐Dependent H3K9me3 Regulation

open access: yesCell Proliferation, EarlyView.
FAM20C regulates the composition of the YTHDC1‐NCL‐KAP1‐LINE1 RNAs complex, thereby affecting neuronal differentiation in hypoxic–ischemic brain damage (HIBD). ABSTRACT Neurodevelopmental impairment due to hypoxic–ischemic brain damage (HIBD) lacks effective biomarkers and therapeutic targets.
Chen‐xi Feng   +8 more
wiley   +1 more source

Cardiac Muscle Membrane Stabilization in Myocardial Reperfusion Injury. [PDF]

open access: yesJACC Basic Transl Sci, 2019
Houang EM   +6 more
europepmc   +1 more source

Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases

open access: yesCell Proliferation, EarlyView.
HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang   +4 more
wiley   +1 more source

Identification of splenic IRF7 as a nanotherapy target for tele-conditioning myocardial reperfusion injury. [PDF]

open access: yesNat Commun
Long Q   +26 more
europepmc   +1 more source

Fibroblast growth factors in myocardial ischemia / reperfusion injury and ischemic preconditioning [PDF]

open access: hybrid, 2001
Pedro Cuevas   +2 more
openalex   +1 more source

Cardiac troponin at the point of care in acute and chronic coronary syndromes

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract High‐sensitivity cardiac troponin (hs‐cTn) assays are integral to the assessment of patients with acute chest pain where prompt and accurate diagnosis of myocardial infarction enables timely delivery of potentially life‐saving treatment. In the Emergency Department, implementation of central laboratory hs‐cTn assays has reduced length of stay ...
Michael McDermott   +4 more
wiley   +1 more source

Cardioprotective effects of the extracellular chaperone clusterin in acute myocardial infarction

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
In vivo, CLU−/− mice were more susceptible to acute myocardial infarction than CLU+/+ mice. Moreover, inflammation and histone levels were significantly increased in CLU−/− mice compared to CLU+/+ mice following ischemia/reperfusion. In vitro, CLU protects cardiomyocytes from histone‐ and/or hypoxia‐induced cell death.
Louwana Allawa   +12 more
wiley   +1 more source

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