Results 251 to 260 of about 131,479 (353)

Insights from animal models: Dissecting the independent roles of oxygen and nutrients in the fetal origins of cardiovascular disease

The Journal of Physiology, EarlyView.
Abstract figure legend This review utilized animal models of complicated human pregnancies that result in reduced fetal nutrient or oxygen delivery, or combined nutrient and oxygen delivery, to elucidate their independent and/or synergistic contributions to the development of high‐risk cardiac phenotypes.
Melanie R. Bertossa, Jack R. T. Darby, Ashley S. Meakin, Mitchell C. Lock, Steven K. S. Cho, Christopher K. Macgowan, Mike. Seed, Michael D. Wiese, Janna L. Morrison   +8 more
wiley   +1 more source

Circular RNAs: Unlocking new avenues in cardiometabolic disease management

The Journal of Physiology, EarlyView.
Abstract figure legend In the heart circular RNAs (circRNAs) function as microRNA sponges, interact with proteins and can even undergo translation. Advances in bioinformatics now enable their identification through high‐throughput RNA sequencing, whereas computational analyses reveal differential expression in cardiac disease settings.
Kimberley M. Mellor, Thomas D. Donelly, Gerald L.M. Naepi, Glenn D. Wadley, Bianca C. Bernardo   +4 more
wiley   +1 more source

Mesenchymal Stem Cell-Derived Extracellular Vesicles in Myocardial Ischemia-Reperfusion Injury: A Comprehensive Review. [PDF]

Biology (Basel)
Bonanni L, Ferri N.
europepmc   +1 more source

Targeting the Mitochondrial Permeability Transition Pore: A Translational Approach to Prevent Myocardial Reperfusion Injury in Delayed Percutaneous Coronary Intervention

İlyas Mammadyarov, Babak Bahrami
openalex   +2 more sources

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, Volume 13, Issue 19, 2 April 2026.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

Chaperone‐Mediated Autophagic Degradation of USP9X in Macrophages Exacerbates Postmyocardial Infarction Inflammation and Cardiac Dysfunction

Advanced Science, Volume 13, Issue 19, 2 April 2026.
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang, Xiangheng Cai, Mengqi Li, Xue Liu, Junhui Xue, Ye Liu, Ding Ai, Xinyang Hu   +7 more
wiley   +1 more source

Mechanistic Insights into the Cardioprotective Effects of Mesenchymal Stem Cell-Derived Exosomes in Myocardial Ischemic Injury: A Systematic Review. [PDF]

Pharmaceutics
Othman Basri NA, Che Roos NA, Aminuddin A, A Hamid A, Hui CK, Mahadi MK, Kumar J, Ugusman A.   +7 more
europepmc   +1 more source

Additional file 1: Figure S1. of Bacopa monnieri extract increases rat coronary flow and protects against myocardial ischemia/reperfusion injury

, 2017
Sirintorn Srimachai, Sylvie Devaux, Céline Demougeot, Sarawut Kumphune, Nina D. Ullrich, Ernst Niggli, Kornkanok Ingkaninan, Natakorn Kamkaew, C. Scholfield, Sompol Tapechum, Krongkarn Chootip   +10 more
openalex   +1 more source

Association of Eosinophil Counts and Ratios With Clinical Outcomes After Acute Ischemic Stroke

Brain and Behavior, Volume 16, Issue 4, April 2026.
This study demonstrates for the first time that low peripheral eosinophil levels are independent predictors of adverse 5‐year outcomes in ischemic stroke or TIA patients, providing a novel basis for risk stratification and future mechanistic research.
Yangying Lu, Lei Zhang, Hongyi Yan, Yuesong Pan, Jing Jing, Xia Meng, Xingquan Zhao, Liping Liu, Yilong Wang, Yongjun Wang, Honglian Wang, Wenchao Li, Bihong Zhu   +12 more
wiley   +1 more source

Oxycodone: A Pain-Relieving Agent With Cardioprotective Properties Against Myocardial Ischemia-Reperfusion Injury. [PDF]

Cardiovasc Ther
Firoozabadi MD, Nooralishahi B, Rezaei-Tazangi F.   +2 more
europepmc   +1 more source