Results 241 to 250 of about 123,463 (303)

A Novel Mechanism of Salvianolic Acid B in Postmyocardial Infarction Cardiac Protection: PHB1‐Driven Raf‐ERK Pathway Activation Promotes Cardiomyocyte Mitosis

MedComm, Volume 7, Issue 5, May 2026.
SalB binds to the C‐terminal of PHB1/2 heterodimer, inducing a conformational change that enhances Raf‐ERK pathway activation via Akt‐mediated phosphorylation, thereby promoting cardiomyocyte mitosis. ABSTRACT Heart failure (HF) following myocardial infarction remains a leading cause of global morbidity and mortality, necessitating novel therapeutic ...
Ce Cao, Bo Ma, Jian Zhang, Lili Yang, Zixin Liu, Haoran Li, Jianshu Song, Keer Zhang, Lei Li, Jianhua Fu, Jianxun Liu   +10 more
wiley   +1 more source

Dihydromyricetin confers protection against myocardial ischemia-reperfusion injury by inhibiting ferroptosis through direct targeting of PPARα. [PDF]

Front Pharmacol
Jin B, Zhang Y, Lin J, Zhu Y, Yang M, Zhang Y, Yin Y, Zhang Z, Yang M, Jiang J, Mi Y.   +10 more
europepmc   +1 more source

Efferocytosis: Signaling Pathways and New Therapeutic Strategies for Diseases

MedComm, Volume 7, Issue 5, May 2026.
1. Efferocytosis coordinates molecular signaling and metabolic reprogramming to resolve inflammation. 2. Efferocytosis dysfunction underlies four conserved pathological hallmarks across diseases. 3. Therapeutic strategies targeting efferocytosis should be context‐dependent: enhance or inhibit based on disease type. ABSTRACT Efferocytosis—the phagocytic
Lei Wang, Jingjing Ge, Zehua Wang, Yihua Fang, Yongxu Jia, Ruyue Zhang, Yanru Qin   +6 more
wiley   +1 more source

Correction to "A Meta-Analysis of Randomized Controlled Trials (RCTs) Investigating the Efficacy and Safety of Acupuncture in Treating Myocardial Ischemia/Reperfusion (I/R) Injury". [PDF]

Cardiol Res Pract
europepmc   +1 more source

S-nitrosoglutathione preserves vasodilation and attenuates myocardial ischemia-reperfusion injury. [PDF]

Sci Rep
Guizoni DM, Pinto Junior EA, Gomes ÉIL, Davel AP, Sposito AC, de Oliveira MG.   +5 more
europepmc   +1 more source

The Association Between Serum MOTS-c Levels and Myocardial Ischemia-Reperfusion Injury in Patients with Acute Myocardial Infarction: A Cross-Sectional Study. [PDF]

Biomedicines
Peng L, Li Y, Duan X, Long J, Ran Q, Zeng X, Liu B, Wang D, Yang J.   +8 more
europepmc   +1 more source

Ferroptosis: key regulatory pathways and their implications in cardiovascular pathophysiology. [PDF]

Front Cardiovasc Med
Cao K, Peng X, Wang X.
europepmc   +1 more source

NMRK2-YAP-NADK axis preserves redox protection against myocardial ischemia/reperfusion injury. [PDF]

Redox Biol
Zhang C, Wang J, Chi J, Liu ST, Meng XW, Li LG, Dong S, Cao H, Zhou XG, Zhang Y, Sun HY, Kang PP, Peng K, Ji FH.   +13 more
europepmc   +1 more source

Oxycodone: A Pain-Relieving Agent With Cardioprotective Properties Against Myocardial Ischemia-Reperfusion Injury. [PDF]

Cardiovasc Ther
Firoozabadi MD, Nooralishahi B, Rezaei-Tazangi F.   +2 more
europepmc   +1 more source

Myocardial ischemia reperfusion in diabetes: mechanism of injury and its drug treatment. [PDF]

Diabetol Metab Syndr
Duan PH, Li HX, Li JH, Xing LP, Liu AN, Wang CH, Fei K.   +6 more
europepmc   +1 more source