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Cell Biochemistry and Function, 2020
Cardiovascular diseases are known to be the most fatal diseases worldwide. Ischaemia/reperfusion (I/R) injury is at the centre of the pathology of the most common cardiovascular diseases.
M. Gunata, H. Parlakpınar
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Cardiovascular diseases are known to be the most fatal diseases worldwide. Ischaemia/reperfusion (I/R) injury is at the centre of the pathology of the most common cardiovascular diseases.
M. Gunata, H. Parlakpınar
semanticscholar +1 more source
Connexin43 and Myocardial Ischemia-Reperfusion Injury
Cardiovascular & Hematological Disorders-Drug Targets, 2018Recently, the treatment and prevention of ischemic cardiomyopathy is one of the emerging research topics in the cardiovascular field. Gap junction is the basic structure of cardiac electrophysiology. Connexin is the basic unit of gap junctions. Connexin43(CX43) is the most abundant member of Cx family in the heart, the normal expression of Cx43 is ...
Lingyun Zu +4 more
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Cardiovascular Research, 2020
BACKGROUND Either insufficient or excessive autophagy causes cellular death and contributes to myocardial ischemia/reperfusion (I/R) injury. However, mechanisms controlling the "right-level" of autophagy in the heart remains unidentified.
Chao Gao +13 more
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BACKGROUND Either insufficient or excessive autophagy causes cellular death and contributes to myocardial ischemia/reperfusion (I/R) injury. However, mechanisms controlling the "right-level" of autophagy in the heart remains unidentified.
Chao Gao +13 more
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Unresolved issues in myocardial reperfusion injury
Cardiovascular Pathology, 2010While the basic pathobiology of myocardial ischemic injury and reperfusion has been determined over the last 50 years, there are important, unresolved, or at least not completely elucidated, issues in the field. These include the relative contributions of different modes of cell injury and death to evolving myocardial infarcts; interactions of ...
L M Buja +5 more
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Echocardiography in Myocardial Reperfusion Injury
2012Assessment of all parameters related to myocardial reperfusion injury can be obtained by echocardiography, an ultrasound-based, noninvasive, radiation-free, and widely available imaging technique. Echocardiography allows the measurement of left ventricular regional and global function, of the area at risk and the infarct size, and estimates ...
Mariana Mirabel, Denis Pellerin
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Myocardial Reperfusion Injury: The Critical Challenge
Critical Care Nursing Clinics of North America, 1992Oxygen-free radical production and reperfusion injury are complex mechanisms. New and improved methods for maximizing the benefits of reperfusion while minimizing reperfusion injury are on the horizon in the 1990s. Critical care nurses play a crucial role in the assessment, planning, and intervention of patients experiencing the deleterious effects of ...
Vicki J. Coombs +2 more
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Management of Myocardial Reperfusion Injury
2012Preface.- Introduction.- Myocardial reperfusion injury: The clinical importance and magnitude of the problem, JC Kaski and G Ambrosio.- Section I. Myocardial reperfusion injury - Pathophysiology and molecular mechanisms.- The "no-reflow phenomenon" leading to myocardial injury and dysfunction- Consequences of reperfusion injury: Pathophysiology and ...
Derek J. Hausenloy +3 more
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Lethal Myocardial Reperfusion Injury
2012Early coronary artery reperfusion reduces infarct size and mortality and improves left ventricular contractile performance after myocardial ischemia compared to permanent occlusion. However, reperfusion itself causes either an acceleration of injury that is not present during ischemia or causes de novo reversible and lethal injury to heart tissue.
Amanda J. Zatta +3 more
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The zinc transporter ZIP7 (Slc39a7) controls myocardial reperfusion injury by regulating mitophagy
Basic Research in Cardiology, 2021Hualu Zhang +10 more
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Targeted pharmacotherapy for ischemia reperfusion injury in acute myocardial infarction
Expert Opinion on Pharmacotherapy, 2020Introduction Achieving reperfusion immediately after acute myocardial infarction improves outcomes; despite this, patients remain at a high risk for mortality and morbidity at least for the first year after the event.
A. Rout +4 more
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