Results 41 to 50 of about 131,479 (353)

The 10th Biennial Hatter Cardiovascular Institute workshop: cellular protection—evaluating new directions in the setting of myocardial infarction, ischaemic stroke, and cardio-oncology [PDF]

, 2018
Due to its poor capacity for regeneration, the heart is particularly sensitive to the loss of contractile cardiomyocytes. The onslaught of damage caused by ischaemia and reperfusion, occurring during an acute myocardial infarction and the subsequent ...
A Ames 3rd, A Carvalho, A Gaspar, A Maulik, AA Neuhaus, AC Schinzel, AD Sloth, Arjun K. Ghosh, AS Hazell, B Ibanez, B Ibanez, Borja Ibanez, CC Smith, CE Murry, CP Baines, D Li, Daniel I. Bromage, Derek M. Yellon, DI Bromage, DJ Hausenloy, DJ Hausenloy, DJ Hausenloy, DJ Hausenloy, DJ Hausenloy, ET Chouchani, F Chauveau, F Chen, F Pedersen, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, G Heusch, GA Donnan, GA Donnan, Gerd Heusch, GF Baxter, GP Fadini, GW Stone, H Sandhu, HA Cabrera-Fuentes, Hans Erik Bøtker, HE Botker, Helen Maddock, I Eitel, J Aronowski, J Astrup, J Bai, J Inserte, J Johnsen, JC Wang, JE Jung, JL Saver, JM Vicencio, John Cunningham, JP Audia, JPG Sluijter, JS Balami, JV McGowan, K Szummer, KL Furie, L Zhang, M Fisher, M Gharanei, M Gharanei, M Schmidt, M Thielmann, Malcolm Walker, Marlene Wiart, Maryna V. Basalay, MD Ginsberg, Michel Ovize, MV Cohen, N Nighoghossian, P Kleinbongard, P Meybohm, PA Lapchak, PA Lapchak, Petra Kleinbongard, R Bell, R Bonita, R Chung, R Madonna, RA Kloner, Richard D. Carr, RM Bell, RM Bell, Robert M. Bell, RR Liu, RR Moustafa, S Lecour, S Pundik, SA Crone, Sandrine Lecour, Sapna Arjun, Sean M. Davidson, SI Savitz, SM Davidson, SM Davidson, SM Davidson, SM Davidson, SP Jones, TA Zelniker, VE O’Collins, VE O’Collins, VL Feigin, W Li, X Rossello, X Rossello, X Xu, Y Li, Z Vermeulen   +117 more
core   +6 more sources

Platelets in Myocardial Ischemia/Reperfusion Injury

Hämostaseologie, 2022
AbstractCoronary artery disease, including myocardial infarction (MI), remains a leading cause of global mortality. Rapid reperfusion therapy is key to the improvement of patient outcome but contributes substantially to the final cardiac damage. This phenomenon is called “ischemia/reperfusion injury (IRI).” The underlying mechanisms of IRI are complex ...
Schanze, Nancy, Hamad, Muataz Ali, Nührenberg, Thomas G., Bode, Christoph, Dürschmied, Daniel Frank   +4 more
openaire   +3 more sources

Phosphomimetic modulation of eNOS improves myocardial reperfusion and mimics cardiac postconditioning in mice. [PDF]

PLoS ONE, 2014
Myocardial infarction resulting from ischemia-reperfusion injury can be reduced by cardiac postconditioning, in which blood flow is restored intermittently prior to full reperfusion.
Terrence Pong, Marielle Scherrer-Crosbie, Dmitriy N Atochin, Kenneth D Bloch, Paul L Huang   +4 more
doaj   +1 more source

Post-TTM Rebound Pyrexia after Ischemia-Reperfusion Injury Results in Sterile Inflammation and Apoptosis in Cardiomyocytes [PDF]

, 2019
Introduction. Fever is frequently observed after acute ischemic events and is associated with poor outcome and higher mortality. Targeted temperature management (TTM) is recommended for neuroprotection in comatose cardiac arrest survivors, but pyrexia ...
Berger, Felix, Garlen, Nalina N. A. von, Krech, Jana, Lam, Phuong D., Schmitt, Katharina R. L., Tong, Giang, Wowro, Sylvia J.   +6 more
core   +1 more source

Combined Right and Left Ventricular Reperfusion Injury Following Percutaneous Coronary Intervention: Role of Myocardial Contrast Echocardiography

Journal of the Indian Academy of Echocardiography & Cardiovascular Imaging, 2023
Right ventricular myocardial infarction (RVMI) occurs in up to half of the patients of inferior wall myocardial infarction. RVMI results in edema and increased right ventricular (RV) mass, and hence, it should be possible to visualize microvascular ...
Madhu Shukla, Jagdish Chander Mohan
doaj   +1 more source

Curcumin attenuates myocardial ischemia-reperfusion injury

Oncotarget, 2017
Cardiovascular diseases (CVDs) are at a badly high-risk of morbidity and mortality in the world.Our study was attempted to investigate the cardioprotective role of curcumin. Hearts injury was assessed in isolated hearts and the rats of coronary artery ligated.The inhibition of pro-inflammatory cytokines was observed by curcumin in coronary artery ...
Liu, Kun, Chen, Honglin, You, Qing-Sheng, Ye, Qing, Wang, Fei, Wang, Shuo, Zhang, Shuang-Long, Yu, Kang-Jun, Lu, Qi   +8 more
openaire   +3 more sources

Fructose 1,6-diphosphate alleviates myocardial ischemia reperfusion injury in rats through JAK2/STAT3 pathway

Asian Pacific Journal of Tropical Medicine, 2018
Objective: To study the effect of fructose 1,6-diphosphate (FDP) on myocardial ischemia reperfusion injury in rats and its molecular mechanism. Methods: Male SPF SD rats were selected as experimental animals and randomly divided into four groups.
Ju-Fei Wang, Cheng Jiang
doaj   +1 more source

Cardiac-derived CTRP9 protects against myocardial ischemia/reperfusion injury via calreticulin-dependent inhibition of apoptosis. [PDF]

, 2018
Cardiokines play an essential role in maintaining normal cardiac functions and responding to acute myocardial injury. Studies have demonstrated the heart itself is a significant source of C1q/TNF-related protein 9 (CTRP9). However, the biological role of
Feng, Pan, Gao, Erhe, Lau, Wayne Bond, Ma, Xin-Liang, Qin, Zhigang, Sun, Yang, Tan, Yanzhen, Xu, Xuezeng, Yang, Jian, Yi, Dinghua, Yi, Wei, Yu, Shiqiang, Zhang, Zhengbin, Zhao, Dajun   +13 more
core   +2 more sources

The Safety and Efficacy of Intravascular Lithotripsy in the Treatment of Severe Coronary Artery Calcification in 261 Cases: A Retrospective Study

Health Science Reports
Background Coronary artery calcification is strongly linked to factors such as advanced age, dyslipidemia, and chronic kidney disease. Severe coronary artery calcification significantly elevates the complexity and risk of percutaneous coronary ...
Tiankun Wu, Honghui Yang, Guian Xu, Qingman Li, Lijie Zhu, Yapan Yang, Tingjie Yang   +6 more
doaj   +1 more source

Myocardial ischemia reperfusion injury is alleviated by curcumin-peptide hydrogel via upregulating autophagy and protecting mitochondrial function

Stem Cell Research & Therapy, 2021
Background Ischemia-reperfusion injury (IRI) is an important factor limiting the success of cardiac reperfusion therapy. Curcumin has a significant cardioprotective effect against IRI, can inhibit ventricular remodeling induced by pressure load or MI ...
Chi-Lin Liao, Yang Liu, Meng-Zhao Huang, Hua-Yong Liu, Zi-Liang Ye, Qiang Su   +5 more
doaj   +1 more source