Results 21 to 30 of about 1,258,622 (242)

Optimising coronary reperfusion in acute myocardial infarction: the role of primary angioplasty [PDF]

, 2007
PhDThrombolysis remains the predominant reperfusion strategy for ST segment elevation myocardial infarction (STEMI) in the United Kingdom. Although primary angioplasty may offer superior outcomes, the logistics of delivering this therapy in the UK ...
Smith, Elliot J
core   +4 more sources

Intravenous sphingosylphosphorylcholine protects ischemic and postischemic myocardial tissue in a mouse model of myocardial ischemia/reperfusion injury [PDF]

, 2010
HDL, through sphingosine-1-phosphate (S1P), exerts direct cardioprotective effects on ischemic myocardium. It remains unclear whether other HDL-associated sphingophospholipids have similar effects.
Bodo Levkau, Levkau, Bodo, Herrgott, Ilka, Johanning, Kai, Echtermeyer, Frank, Chun, Jerold, Hildebrand, Reinhard, Ilka Herrgott, Gregor Theilmeier, Christine Herzog, Winterhalter, Michael, Frank Ulrich Müller, Schmitz, Martina, Müller, Frank Ulrich, Jan Mersmann, Michael Winterhalter, Reinhard Hildebrand, Martina Schmitz, Herzog, Christine, Frank Echtermeyer, Jerold Chun, Theilmeier, Gregor, Mersmann, Jan, Larmann, Jan, Jan Larmann, Kai Johanning   +25 more
core   +1 more source

Tumor Necrosis Factor-α Contributes to Ischemia- and Reperfusion-Induced Endothelial Activation in Isolated Hearts [PDF]

, 1999
During myocardial reperfusion, polymorphonuclear neutrophil (PMN) adhesion involving the intercellular adhesion molecule-1 (ICAM-1) may lead to aggravation and prolongation of reperfusion injury.
Kelly, Ralph A., Stefan Zahler, Habazettl, Helmut, Goedecke, Axel, Becker, Bernhard F., Dieter A. Wolf, Christian Kupatt, Helmut Habazettl, Boekstegers, Peter, Bernhard F. Becker, Kupatt, Christian, Peter Boekstegers, Zahler, Stefan, Wolf, Dieter A., Ralph A. Kelly, Axel Goedecke   +15 more
core   +1 more source

Transient limb ischemia induces remote ischemic preconditioning in vivo [PDF]

, 2002
Background-Ischemic preconditioning reduces local tissue injury caused by subsequent ischemia-reperfusion (IR), but may also have a salutary effect on IR injury of tissues remote from those undergoing preconditioning.
Hoschtitzky, JA, Sorensen, K, Redington, AN, Mortensen, UM, Kristiansen, SB, Kharbanda, RK, Vogel, M, Kharbanda, Rajesh, White, PA, Schmidt, MR, MacAllister, R   +10 more
core   +1 more source

Protecting the ischemic heart : pharmacological protection against myocardial ischemia in rats in vivo and in vitro [PDF]

, 2004
Today in Switzerland approximately 40% of all deaths are due to cardiovascular diseases. More than half of these are due to ischemic heart disease. Among the fatal consequences of ischemic heart disease are life-threatening arrhythmias and myocardial ...
Butz, Silvia
core   +1 more source

Microvascular damage is associated with carotid wall structural changes in Systemic Sclerosis: a capillaroscopy and ultrasound‐based observational study

Arthritis Care &Research, Accepted Article.
Introduction Systemic sclerosis (SSc) is characterized by cardiovascular risk excess not fully explained by traditional factors. Whether the severity of microvascular damage correlates with structural subclinical atherosclerosis remains unclear. We investigated the relationship between nailfold videocapillaroscopy (NVC) abnormalities and carotid ...
Eugenio Capparelli, Luca Clerici, Francesco Lapia, Giusy C. Moltisanti, Eleonora Zaccara, Greta Pellegrino, Daniela Bompane, Francesca Capelli, Letizia Ferrami, Laura Castelnovo, Antonio Tamburello, Maria Sole Chimenti, Paola Faggioli, Antonino Mazzone   +13 more
wiley   +1 more source

A K_ATP channel opener inhibited myocardial reperfusion action potential shortening and arrhythmias [PDF]

, 2001
Low concentrations of certain K_ATP channel openers have been reported to exert a moderate inhibitory effect on arrhythmias during post-ischaemic early myocardial reperfusion, but the accompanying effects on the time course of ...
Northover, B.J., Ian MacKenzie, Basil J Northover, Antony J Workman, MacKenzie, I., Workman, A.J.   +5 more
core   +1 more source

Biointegrated Battery‐Based Electroceuticals

Advanced Materials, EarlyView.
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou, Zhilian Yue, Zhiqi Chen, Danming Chao, Xiaoteng Jia, Gordon Wallace, Caiyun Wang   +6 more
wiley   +1 more source

Release of TNF-α during myocardial reperfusion depends on oxidative stress and is prevented by mast cell stabilizers [PDF]

, 2003
Objectives: Our study sought to elucidate the role of oxidative stress for shedding of tumor necrosis factor-α (TNF-α) and for activating TNF-α-converting enzyme (TACE).
Welsch, Ulrich, Sommerhoff, Christian P., Gilles, Stefanie, Zahler, Stefan, Becker, Bernhard F.   +4 more
core   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source