Results 41 to 50 of about 188,975 (215)

Phosphomimetic modulation of eNOS improves myocardial reperfusion and mimics cardiac postconditioning in mice. [PDF]

PLoS ONE, 2014
Myocardial infarction resulting from ischemia-reperfusion injury can be reduced by cardiac postconditioning, in which blood flow is restored intermittently prior to full reperfusion.
Terrence Pong, Marielle Scherrer-Crosbie, Dmitriy N Atochin, Kenneth D Bloch, Paul L Huang   +4 more
doaj   +1 more source

Fructose 1,6-diphosphate alleviates myocardial ischemia reperfusion injury in rats through JAK2/STAT3 pathway

Asian Pacific Journal of Tropical Medicine, 2018
Objective: To study the effect of fructose 1,6-diphosphate (FDP) on myocardial ischemia reperfusion injury in rats and its molecular mechanism. Methods: Male SPF SD rats were selected as experimental animals and randomly divided into four groups.
Ju-Fei Wang, Cheng Jiang
doaj   +1 more source

The Safety and Efficacy of Intravascular Lithotripsy in the Treatment of Severe Coronary Artery Calcification in 261 Cases: A Retrospective Study

Health Science Reports
Background Coronary artery calcification is strongly linked to factors such as advanced age, dyslipidemia, and chronic kidney disease. Severe coronary artery calcification significantly elevates the complexity and risk of percutaneous coronary ...
Tiankun Wu, Honghui Yang, Guian Xu, Qingman Li, Lijie Zhu, Yapan Yang, Tingjie Yang   +6 more
doaj   +1 more source

Lactated Ringer's solution for preventing myocardial reperfusion injury

International Journal of Cardiology: Heart & Vasculature, 2017
Reperfusion of ischemic myocardium is crucial for salvaging myocardial cells from ischemic cell death. However, reperfusion itself induces various deleterious effects on the ischemic myocardium.
Takashi Koyama
doaj   +1 more source

Combined Right and Left Ventricular Reperfusion Injury Following Percutaneous Coronary Intervention: Role of Myocardial Contrast Echocardiography

Journal of the Indian Academy of Echocardiography & Cardiovascular Imaging, 2023
Right ventricular myocardial infarction (RVMI) occurs in up to half of the patients of inferior wall myocardial infarction. RVMI results in edema and increased right ventricular (RV) mass, and hence, it should be possible to visualize microvascular ...
Madhu Shukla, Jagdish Chander Mohan
doaj   +1 more source

Resveratrol Protects against Myocardial Ischemia-Reperfusion Injury via Attenuating Ferroptosis.

Gene, 2021
Resveratrol (Res) is a polyphenol with a variety of biological activities. However, whether Res can prevent myocardial ischemia-reperfusion (I/R) injury is not yet known.
Ting Li, Ying Tan, Shao Ouyang, Jin-Chen He, Lingling Liu   +4 more
semanticscholar   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Heart–gut microbiota communication determines the severity of cardiac injury after myocardial ischaemia/reperfusion

Cardiovascular Research, 2023
Aims Recent studies have suggested a key role of intestinal microbiota in pathological progress of multiple organs via immune modulation. However, the interactions between heart and gut microbiota remain to be fully elucidated. The aim of the study is to
Jinxuan Zhao, Qi Zhang, W. Cheng, Qing Dai, Zhonghai Wei, Meng Guo, Fu Chen, Shuaihua Qiao, Jiaxin Hu, Junzhuo Wang, Haiting Chen, Xue Bao, Dan Mu, Xuan Sun, Biao Xu, Jun Xie   +15 more
semanticscholar   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Myocardial ischemia reperfusion injury is alleviated by curcumin-peptide hydrogel via upregulating autophagy and protecting mitochondrial function

Stem Cell Research & Therapy, 2021
Background Ischemia-reperfusion injury (IRI) is an important factor limiting the success of cardiac reperfusion therapy. Curcumin has a significant cardioprotective effect against IRI, can inhibit ventricular remodeling induced by pressure load or MI ...
Chi-Lin Liao, Yang Liu, Meng-Zhao Huang, Hua-Yong Liu, Zi-Liang Ye, Qiang Su   +5 more
doaj   +1 more source