Ischemic preconditioning affects phosphosites and accentuates myocardial stunning while reducing infarction size in rats [PDF]
Background and aimsIschemic preconditioning (IPC), i.e., brief periods of ischemia, protect the heart from subsequent prolonged ischemic injury, and reduces infarction size. Myocardial stunning refers to transient loss of contractility in the heart after
Ahmed Elmahdy+31 more
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ATP—Sensitive Potassium Channel Opener Diazoxide Reduces Myocardial Stunning in a Porcine Regional With Subsequent Global Ischemia Model [PDF]
Background ATP‐sensitive potassium channels are inhibited by ATP and open during metabolic stress, providing endogenous myocardial protection. Pharmacologic opening of ATP potassium channels with diazoxide preserves myocardial function following ...
Ana K. Velez+10 more
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Myocardial stunning in hyperthyroidism [PDF]
AbstractThe cases of two patients with hyperthyroidism and acute left ventricular (LV) dysfunction with segmental wall motion abnormalities resulting in heart failure are reported. Both had electrocardiographic changes mimicking ischemic coronary artery disease.
Naveen L. Pereira+5 more
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Myocardial stunning secondary to erroneous administration of intravenous epinephrine [PDF]
Epinephrine is a commonly used medication for emergent conditions, such as anaphylaxis, respiratory distress, and shock. However, its versatility can also lead to iatrogenic errors in dosages, concentrations, and routes of administration. In this case, a
Girish Pathangey+3 more
doaj +2 more sources
Myocardial stunning adalah penurunan fungsi miokardium pada periode iskemia dan reperfusi. Iskemia dapat menyebabkan perubahan di dalam struktur miosit yang berusaha mengembalikan aliran darah normal. Salah satu teori yaitu teori “Calcium Overload” dapat
Maria Lousiana, Miftah Irramah
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Serum neprilysin levels are associated with myocardial stunning after ST-elevation myocardial infarction [PDF]
Background Left ventricular remodeling following ST-elevation myocardial infarction (STEMI) is associated with poor outcome, including heart failure (HF).
Damien Legallois+8 more
doaj +2 more sources
Metformin preconditioning protects against myocardial stunning and preserves protein translation in a mouse model of cardiac arrest [PDF]
Cardiac arrest (CA) causes high mortality due to multi-system organ damage attributable to ischemia-reperfusion injury. Recent work in our group found that among diabetic patients who experienced cardiac arrest, those taking metformin had less evidence ...
Cody A. Rutledge+7 more
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Comparison of the proteomic landscape in experimental ischemia reperfusion with versus without ischemic preconditioning [PDF]
Myocardial ischemic preconditioning (IPC) enhances myocardial resilience to ischemic injury. Myocardial stunning is a transient, reversible dysfunction, while necrosis involves irreversible cell death. The relationship between IPC, stunning, and necrosis
Yalda Kakaei+18 more
doaj +2 more sources
Troponin I Degradation and Myocardial Stunning [PDF]
To the Editor: The article by Feng et al1 caused a revolution in current thinking regarding the pathomechanism involved in myocardial stunning, in that it irrefutably proved that there is no causal link between troponin I (TnI) degradation and the transiently depressed contractile function after a brief ischemic episode.
Z. Papp, Judit Barta, Ger J.M. Stienen
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Pentobarbital-Induced Myocardial Stunning in Status Epilepticus Requiring Extracorporeal Membrane Oxygenation: A Case Report and Literature Review [PDF]
Introduction. Mild hypotension is a well-recognized complication of intravenous pentobarbital; however fulminant cardiopulmonary failure has not been previously reported. Case Report.
Tapan Kavi+4 more
doaj +2 more sources