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Journal of Cardiac Surgery, 1993
The use of animal models is a valuable approach to the elucidation of the pathophysiology of myocardial stunning. Coronary occlusion followed by reperfusion produces stunning experimentally, mimicking a myocardial infarction followed by thrombolysis, angioplasty, or coronary bypass.
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The use of animal models is a valuable approach to the elucidation of the pathophysiology of myocardial stunning. Coronary occlusion followed by reperfusion produces stunning experimentally, mimicking a myocardial infarction followed by thrombolysis, angioplasty, or coronary bypass.
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Myocardial Stunning Following Respiratory Arrest
Chest, 1995Myocardial stunning is defined as a prolonged myocardial dysfunction with gradual return of contractile activity after a brief episode of severe ischemia. Usually it is seen in patients with myocardial infarction following treatment with thrombolytic agents, in patients with angina, and in patients recovering from cardiopulmonary bypass surgery.
R, Bashir, F A, Padder, F A, Khan
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Myocardial Stunning after Electroconvulsive Therapy
Annals of Internal Medicine, 1992Excerpt Myocardial stunning (1, 2), a prolonged but reversible myocardial contractile dysfunction, has not been reported after electroconvulsive therapy (ECT).
W X, Zhu +3 more
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Mechanisms Underlying Myocardial Stunning
Journal of Cardiac Surgery, 1993The effect of myocardial stunning on mitochondrial function was examined in rabbit hearts. After global normothermic ischemia followed by reperfusion, we previously found that mitochondrial high energy phosphate content was not significantly diminished.
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Myocardial Stunning: An Overview
Journal of Cardiac Surgery, 1993Over the past two decades, we have challenged the belief that transient ischemia is benign with little functional sequelae following resolution of ischemia. The phenomenon of prolonged postischemic contractile dysfunction, or of myocardial stunning, has been developed and is under investigation using multiple experimental and clinical models ...
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Myocardial stunning after successful defibrillation
Resuscitation, 2008A 75-year-old man presented to the emergency department with syncope. His ECG rhythm showed a broad complex tachycardia. After synchronized cardioversion with a monophasic 100 J shock he developed coarse ventricular fibrillation. The initial rhythm after the shock was sinus rhythm with no pulse or signs of life.
Sandroni, Claudio +3 more
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Cellular Mechanisms of Myocardial Stunning
Annual Review of Physiology, 1992Stunning describes the impairment of contraction observed in myocardium that has been reperfused after brief periods of ischemia (12, 31, 90). The critical feature of the definition lies in the premise that no permanent injury has occurred; hence, stunning resolves entirely, albeit slowly (hours to days; 12).
H, Kusuoka, E, Marban
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Independency of myocardial stunning of endothelial stunning?
Basic Research in Cardiology, 2007Vascular endothelial cells play an important role in the control of vascular tone. The reasons for coronary endothelial dysfunction are complex and may involve ischemia/reperfusion injury. We investigated whether endothelial, smooth muscle, and myocardial dysfunction are independent phenomena.Rabbit hearts were rapidly excised without intermittent ...
Solange C, Garcia +4 more
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Myocardial “Stunning” and Substrate Metabolism
Journal of Cardiac Surgery, 1994Although many experts have dismissed myocardial substrate metabolism as having a role in the phenomenon known as "myocardial stunning," recent studies using the isolated perfused working rat heart (especially from Lopaschuk's laboratory) have provided evidence that perhaps there is a role for alterations in myocardial substrate metabolism in producing ...
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Oxygen Radicals and Myocardial Stunning
Journal of Cardiac Surgery, 1994There is compelling, although indirect, evidence that oxygen free radicals, generated during ischemia as well as upon reperfusion and reoxygenation of the ischemic heart, contribute to the reversible ventricular dysfunction characterized as myocardial stunning.
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