Results 51 to 60 of about 14,322 (328)

Liquiritin Exerts a Dual Effect on BMSCs Osteogenic Differentiation and Fracture Healing by Activating the ERK/JNK Pathway and Providing Antioxidant Protection

Advanced Therapeutics, EarlyView.
Liquiritin enhances the osteogenic differentiation of BMSCs and promotes fracture healing through the activation of the ERK/JNK signaling pathway and by exerting antioxidant protective effects. Abstract Liquiritin, a flavonoid from Glycyrrhiza uralensis L., has diverse pharmacological properties, but its impact on fracture healing is unexplored.
Haijun Mao, Jing Liu, Juan Feng, Yalikun Yusufu, Lei Yang, Qing Jiang, Minghui Sun   +6 more
wiley   +1 more source

The role of Volatile Anesthetics in Cardioprotection: a systematic review. [PDF]

, 2012
This review evaluates the mechanism of volatile anesthetics as cardioprotective agents in both clinical and laboratory research and furthermore assesses possible cardiac side effects upon usage.
Applegate, Richard L, Krafft, Paul R, Leitzke, Arthur S, Tang, Jiping, Van Allen, Nicole R, Zhang, John H   +5 more
core   +1 more source

Bridging the Gap in a Rare Cause of Angina

European Cardiology Review, 2021
Myocardial bridging occurs when coronary arteries run intramurally. Episodes of tachycardia can cause a dynamic obstruction that extends into diastole, compromising coronary filling time, and subsequently leading to ischaemia. Myocardial ischaemia, acute
Sumanth Khadke, Jovana Vidovic, Vinod Patel   +2 more
doaj   +1 more source

Irisin Attenuates Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension via Ubiquitin‐Mediated Regulation of ENO1

Advanced Science, EarlyView.
Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun, Yong‐Bing Wang, Jing Huang, Run‐Wei Deng, Hui‐Yu He, Lei Gao, Xuan Gao, You‐Li Fan, Yan Cong, Yao‐Lei Guo, Yi‐Qiang Chen, Gui‐Jia Wang, Shao‐Hong Fang, Xia Gu, Bo Yu, Bing‐Xiang Wu   +15 more
wiley   +1 more source

Stretch‐Induced Increase in Cardiac Contractility Is Independent of Myocyte Ca\u3csup\u3e2+\u3c/sup\u3e While Block of Stretch Channels by Streptomycin Improves Contractility After Ischemic Stunning [PDF]

, 2015
Stretching the cardiac left ventricle (LV) enhances contractility but its effect on myoplasmic [Ca2+] is controversial. We measured LV pressure (LVP) and [Ca2+] as a function of intra-LV stretch in guinea pig intact hearts before and after 15 min global ...
Aldakkak, Mohammed, Camara, Amadou KS, Heisner, James S., Rhodes, Samhita S., Stowe, David F.   +4 more
core   +1 more source

SEIZURE-INDUCED MYOCARDIAL STUNNING

Journal of the American College of Cardiology, 2014
A transient LV dysfunction complicating subarachnoid hemorrhage, neurogenic myocardial stunning, has been well described. A similar dysfunction could complicate seizures, a much more prevalent condition, requiring early recognition to prevent complications.
Michael Romanelli, Saif Al-Najafi
openaire   +2 more sources

Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications

Advanced Science, EarlyView.
This review focuses on the immunomodulatory mechanisms of molecular hydrogen, the recent detection methods, and the classification advanced molecular hydrogen delivery materials. It provides a detailed description of their applications in areas such as arthritis, chronic wounds, cardiovascular injury, tumors, and bacterial infections, aiming to enhance
Gangfeng Li, Hannan Cui, Ruixiao Fan, Guming Liu, Zishuo Hou, Yibo Zhang, Xuanming Che, Tengjiao Wang, Hongbo Wei, Peng Li   +9 more
wiley   +1 more source

Effects of successful percutaneous transluminal coronary angioplasty on global and regional left ventricular function in unstable angina pectoris [PDF]

, 1987
Sixty-eight patients (58 men, 10 women, mean age 56.3 years, range 31 to 72) with unstable angina pectoris, either initially stabilized with or refractory to optimal pharmacologic treatment, were studied to determine whether regional dysfunction due to ...
Beatt, K.J. (Kevin), Brand, M.J.B.M. (Marcel) van den, Feyter, P.J. (Pim) de, Hugenholtz, P.G. (Paul), Serruys, P.W.J.C. (Patrick), Suryapranata, H. (Harry)   +5 more
core   +1 more source

Inhibition and Rescue of Hyperglycemia‐Induced Cellular Senescence by Mitochondrial Transfer from Enucleated Mesenchymal Stem Cell‐Derived Microvesicles for Chronic Wound Healing

Advanced Science, EarlyView.
This study develops enucleated MSC‐derived microvesicles (Mito@euMVs) to deliver functional mitochondria for optimizing wound repair. By efficiently encapsulating mitochondria, Mito@euMVs rejuvenate hyperglycemia‐induced senescent fibroblasts and HUVECs. Using PVA microneedle patches, the therapeutic efficacy of Mito@euMVs is validated in diabetic rats
Zixuan Dong, Xiaobing Liu, Shichun Li, Xiaoling Fu   +3 more
wiley   +1 more source

Relation of delayed recovery of myocardial function after takotsubo cardiomyopathy to subsequent quality of life [PDF]

, 2015
Takotsubo cardiomyopathy (TTC) has generally been regarded as a relatively transient disorder, characterized by reversible regional left ventricular systolic dysfunction.
Akashi, Akashi, Bellandi, Betty Raman, Bybee, Christopher J. Neil, Dana Dawson, Dawson, Gianni, Helle-Valle, Jeanette Stansborough, John D. Horowitz, Kuljit Singh, Madhavan, Michael P. Frenneaux, Morel, Nef, Neil, Nguyen, Parodi, Picard, Pilliere, Sharkey, Thanh H. Nguyen, Wittstein, Yoshioka   +25 more
core   +1 more source