Results 81 to 90 of about 181,553 (268)
Advanced Science, EarlyView.This study developed an oral bioinspired peroxisome‐engineered probiotic (BPEP) by anchoring lipid‐encapsulated ruthenium nanozymes onto Escherichia coli Nissle 1917, utilizing probiotics to deliver nanozymes to the intestinal barrier for reactive oxygen species/reactive nitrogen species elimination, tight junction restoration, and gut microbiota ...
Shuyu Wang +10 more
wiley +1 more source
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Advanced Science, EarlyView.Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Advanced Science, EarlyView.This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang +16 more
wiley +1 more source
Printable Conductive Hydrogels for Electrochemical Biosensing and Soft Bioelectronic Interfaces
Advanced Science, EarlyView.Flexible, conductive hydrogels that integrate printability, mechanical tunability, biocompatibility, and electronic performance remain challenging to achieve. Here, we develop 3D‐printable poly(ethylene glycol)–poly(pyrrole)‐ hydrogels with tissue‐like mechanics, high cytocompatibility, and robust electrochemical function.
Lukas Hein +6 more
wiley +1 more source
Российский кардиологический журнал, 2004 Dynamics of left vetriculum and large artery wall elasticity in post-infarctial aneurysm formation are described. Myocardial and vascular status is assessed with a volume-resistance cirulation model.
S. S. Suvorova +2 more
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Advanced Science, EarlyView.ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng +15 more
wiley +1 more source
Advanced Science, EarlyView.A developmentally inspired bioprinting approach enables the fabrication of pluripotent tissues that undergo shape‐morphing and in situ cardiac lineage specification. This method employs embedded bioprinting to deposit iPSCs within soft granular hydrogels to create pluripotent tissue constructs that undergo cell‐mediated shape morphogenesis.
Ankita Pramanick +8 more
wiley +1 more source
Ribogospodarsʹka Nauka UkraïniPurpose. To evaluate the variability of the histological parameters of individual organs and tissues of sterlet, to establish the level of effect of heat stress on the physiological status of fish and the degree of their adaptation.
M. Koziy
doaj +1 more source
The effect of exercise training before and after exposure to breast cancer on Bax and Bcl-2 levels on myocardial tissue in female mice [PDF]
فصلنامه ابن سینا, 2017 Background: Breast cancer is the most common type of cancer among women. Also, the risk of mortality from cardiovascular diseases in these patients is more than other people. Aerobic exercise is effective in the prevention and treatment of cardiovascular
Z Ebrahimpur +3 more
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