Results 101 to 110 of about 124,243 (355)

Calcium signaling in endocardial and epicardial ventricular myocytes from streptozotocin‐induced diabetic rats [PDF]

open access: gold, 2020
Lina T. Al Kury   +7 more
openalex   +1 more source

Fueling cardiac myocyte proliferation

open access: yesThe Journal of Cardiovascular Aging
[Image: see text]
Manisha Deogharia, Priyatansh Gurha
openaire   +2 more sources

Controlling Myocyte cGMP [PDF]

open access: yesCirculation Research, 2009
See related article, pages 956–964 CGMP is a central intracellular second-messenger regulating numerous cellular functions. In the cardiac myocyte, cGMP mediates effects of nitric oxide and atrial natriuretic peptide, whereas its counterpart, cAMP, mediates catecholamine signaling.
openaire   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

open access: yesBMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu   +9 more
wiley   +1 more source

Ninjurin1 regulates striated muscle growth and differentiation.

open access: yesPLoS ONE, 2019
Chronic pressure overload due to aortic valve stenosis leads to pathological cardiac hypertrophy and heart failure. Hypertrophy is accompanied by an increase in myocyte surface area, which requires a proportional increase in the number of cell-cell and ...
Melanie Kny   +14 more
doaj   +1 more source

Altered excitation-contraction coupling in human chronic atrial fibrillation [PDF]

open access: yes, 2012
This review focuses on the (mal)adaptive processes in atrial excitation-contraction coupling occurring in patients with chronic atrial fibrillation. Cellular remodeling includes shortening of the atrial action potential duration and effective refractory ...
Grandi, E., Pandit, S.V., Workman, A.J.
core   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

open access: yesBMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang   +12 more
wiley   +1 more source

Heart-Derived Stem Cells in Miniature Swine with Coronary Microembolization: Novel Ischemic Cardiomyopathy Model to Assess the Efficacy of Cell-Based Therapy

open access: yesStem Cells International, 2016
A major problem in translating stem cell therapeutics is the difficulty of producing stable, long-term severe left ventricular (LV) dysfunction in a large animal model. For that purpose, extensive infarction was created in sinclair miniswine by injecting
Gen Suzuki   +3 more
doaj   +1 more source

Genetically engineered cardiac pacemaker: stem cells transfected with HCN2 gene and myocytes - a model

open access: yes, 2005
Artificial biological pacemakers were developed and tested in canine ventricles. Next steps will require obtaining oscillations sensitive to external regulations, and robust with respect to long term drifts of expression levels of pacemaker currents and ...
Kanani, Sandra   +2 more
core  

Contemporary and Emerging Therapies in the Management of Refractory Angina: A Clinical Review

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Refractory angina (RA) represents a growing challenge in clinical cardiology, particularly in patients with obstructive coronary artery disease (CAD) who remain symptomatic despite optimal medical therapy and who are not candidates for revascularization.
Alex Angers‐Goulet   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy