Results 131 to 140 of about 124,243 (355)

Effects of occlusal disharmony on cardiac fibrosis, myocyte apoptosis and myocyte oxidative DNA damage in mice

, 2020
Yuka Yagisawa, Kenji Suita, Yoshiki Ohnuki, Misao Ishikawa, Yasumasa Mototani, Aiko Ito, Ichiro Matsuo, Yoshio Hayakawa, Megumi Nariyama, Daisuke Umeki, Yasutake Saeki, Yasuharu Amitani, Yoshiki Nakamura, Hiroshi Tomonari, Satoshi Okumura   +14 more
openalex   +1 more source

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

ESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely, Tamás Kovács, Andrea Kovács, Viktória E. Tóth, Nabil V. Sayour, Gábor M. Mórotz, Csenger Kovácsházi, Gábor B. Brenner, Zsófia Onódi, Balázs Enyedi, Domokos Máthé, Przemyslaw Leszek, Zoltán Giricz, Péter Ferdinandy, Zoltán V. Varga   +14 more
wiley   +1 more source

A Broad-Spectrum Chemokine Inhibitor Drives M2 Macrophage Polarization Through Modulation of the Myometrial Secretome

Cells
The uterine smooth muscle (myometrium) is an immunomodulatory tissue capable of secreting multiple chemokines during pregnancy. We propose that before term labor, chemokines secreted as a result of mechanical stretch of the uterine walls by the growing ...
Adam Boros-Rausch, Anna Dorogin, Lubna Nadeem, Oksana Shynlova, Stephen James Lye   +4 more
doaj   +1 more source

Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges

Epilepsia Open, EarlyView.
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus, Cesar Santana‐Gomez, Ruby G. Escalante, Dominique Duncan, Pedro F. Viana, Giulia Sofia Cereda, Naoto Kuroda, Aristea S. Galanopoulou   +7 more
wiley   +1 more source

Dystroglycan Matrix Receptor Function in Cardiac Myocytes Is Important for Limiting Activity-Induced Myocardial Damage [PDF]

, 2009
Daniel E. Michele, Zhyldyz Kabaeva, S. Lindsey Davis, Robert M. Weiß, Kevin P. Campbell   +4 more
openalex   +1 more source

Biomarkers for the estimation of isoproterenol‐induced myocardial infarction: A review of key parameters

Journal of Intelligent Medicine, EarlyView.
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran, Tarique Mahmood, Farogh Ahsan, Shahzadi Bano, Vaseem Ahamad Ansari, Mohd Adnan   +5 more
wiley   +1 more source

Out‐of‐equilibrium pH transients in the guinea‐pig ventricular myocyte [PDF]

, 1998
Chae Hun Leem, Richard D. Vaughan‐Jones   +1 more
openalex   +1 more source

Alcohol Septal Ablation in Hypertrophic Obstructive Cardiomyopathy: Long‐Term Follow‐Up of Deformations and Hemodynamics

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background A detailed evaluation of hemodynamics, supportive morphology, and deformation may help uncover the pathophysiology of hypertrophic obstructive cardiomyopathy (HOCM) and the changes wrought by alcohol septal ablation (ASA). Purpose To investigate the global cardiac volume, myocardial deformation, and hemodynamic characteristics ...
Kenichiro Suwa, Kazuto Ohno, Terumori Satoh, Ryota Sato, Keisuke Iguchi, Yuichiro Maekawa   +5 more
wiley   +1 more source

Antiarrhythmic agents act differently on the activation phase of the ACh‐response in guinea‐pig atrial myocytes [PDF]

, 1993
Norio Inomata, Tomochika Ohno, Takafumi Ishihara, Norio Akaike   +3 more
openalex   +1 more source

Lipofuscin: The Missing Link in the Worsening of Obstructive Sleep Apnea

The Laryngoscope, EarlyView.
Lipofuscin, also known as the age pigment, is a permanent autofluorescent intracellular deposit that accumulates with aging or oxidative stress, thereby interfering with cellular function. This study revealed significantly larger deposits of lipofuscin in the lateral pharyngeal wall muscles of patients with severe obstructive sleep apnea (OSA) compared
Kristine Fahl, Carlos Modesto Vera Palomino, Mauricio da Silva Baptista, Adriano Polican Ciena, Danielle Andrade da Silva Dantas, Luiz Ubirajara Sennes, Marucia Chacur, Michel Burihan Cahali   +7 more
wiley   +1 more source