Results 141 to 150 of about 124,243 (355)

Editorial: Emerging Mechanisms for Skeletal Muscle Mass Regulation

Frontiers in Cell and Developmental Biology, 2021
Yuji Ogura, Shuichi Sato, Yann S. Gallot, Susan Tsivitse Arthur   +3 more
doaj   +1 more source

Mechanisms of Volatile Anesthetic-Induced Myocardial Protection [PDF]

, 2003
Volatile anesthetics protect myocardium against reversible and irreversible ischemic injury. Experimental evidence from several in vitro and in vivo animal models demonstrates that volatile agents enhance the recovery of stunned myocardium and reduce the
Gu, Weidong, Kersten, Judy R., LaDisa, John F., Ludwig, Lynda M., Pagel, Paul S., Tanaka, Katsuya, Warltier, David C.   +6 more
core   +1 more source

Hypoxia‐inducible factor‐1 improves inotropic responses of cardiac myocytes in ageing heart without affecting mitochondrial activity [PDF]

, 2010
Tao Tan, José Marı́n-Garcı́a, Shirish Damle, Harvey R. Weiss   +3 more
openalex   +1 more source

Accelerating virtual patient generation with a Bayesian optimization and machine learning surrogate model

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 486-494, March 2025.
Abstract The pharmaceutical industry has increasingly adopted model‐informed drug discovery and development (MID3) to enhance productivity in drug discovery and development. Quantitative systems pharmacology (QSP), which integrates drug action mechanisms and disease complexities to predict clinical endpoints and biomarkers is central to MID3.
Hiroaki Iwata, Ryuta Saito
wiley   +1 more source

Taurine-magnesium Coordination Compound Attenuates Hypoxia/Reoxygenation Induced Ion Channel Dysfunction in Rat Ventricular Myocytes [PDF]

, 2013
Lin Zhao, Jie Lou, Yi Kang
openalex   +1 more source

Two causes of COVID‐19‐related myocardial injury‐associated cardiogenic shock: Myocarditis and microvascular thrombosis

ESC Heart Failure, Volume 12, Issue 2, Page 1514-1522, April 2025.
Takamasa Iwai, Hirohiko Aikawa, Yoshiaki Morita, Keiko Ohta‐Ogo, Teruo Noguchi   +4 more
wiley   +1 more source

Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development

Environmental Toxicology, EarlyView.
ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo, Patricia Meade, Irene Jiménez‐Salvador, Carmen Hernández‐Ainsa, Eldris Iglesias, Alba Pesini, Nuria Garrido‐Pérez, Sonia Emperador, David Pacheu‐Grau, Pilar Bayona‐Bafaluy, Eduardo Ruiz‐Pesini   +10 more
wiley   +1 more source

Anti‐desmoglein‐2 autoantibodies do not discriminate between UK boxer dogs with and without arrhythmogenic right ventricular cardiomyopathy

Veterinary Record, EarlyView.
Abstract Background Evidence regarding the diagnostic utility of serum anti‐desmoglein‐2 (DSG2) autoantibodies for arrhythmogenic right ventricular cardiomyopathy (ARVC) in boxer dogs is conflicting. Methods Prospective standardised evaluation of apparently healthy boxer dogs for ARVC was performed at three referral centres, including blood pressure ...
Chia‐Hsuan Chang, Claire Watson, Diptendu Chatterjee, Jade Ward, Kieran Borgeat, Hannah Hodgkiss‐Geere, Joanna Dukes‐McEwan, Robert Hamilton, Melanie J. Hezzell   +8 more
wiley   +1 more source

Foetal Cardiac Function in Early Labour and Intrapartum Outcomes: A Prospective Observational Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To assess foetal myocardial deformation in normo‐oxygenated foetuses in early labour and its relationship with intrapartum outcomes. Design Single centre prospective study. Setting Referral tertiary maternity unit. Population Uncomplicated singleton term pregnancies in early labour.
Andrea Dall'Asta, Chiara Melito, Beatrice Valentini, Mariagrazia Capurso, Maria Teresa Baffa, Olga Patey, Basky Thilaganathan, Tullio Ghi   +7 more
wiley   +1 more source

INDUCTION OF BRN-3B/POU4F2 IN CARDIAC MYOCYTES BY ANGIOTENSIN II CAN AFFECT FATE AND SURVIVAL DEPENDING ON CO-EXPRESSION WITH P53 [PDF]

, 2012
S Ounzain, Ricardo Fujita, Jane Clark, Richard J. Heads, Vishwanie Budhram‐Mahadeo   +4 more
openalex   +1 more source