Results 1 to 10 of about 141,107 (310)

Ventricular androgenic-anabolic steroid-related remodeling: an immunohistochemical study [PDF]

, 2017
Background: Several fatal cases of bodybuilders, following a myocardial infarction after long exposure to androgenicanabolic steroids (AAS), are reported. In recent years, evidence has emerged of cases of heart failure related to AAS consumption, with no
Cecchi, Rossana, Ciallella, Costantino, DI LUCA, Natale Mario, Kimura, Akihiko, Kondo, Toshikazu, Muciaccia, Barbara, Nosaka, Mizuho, Sestili, Cristina   +7 more
core   +1 more source

Over expression of Plk1 does not induce cell division in rat cardiac myocytes in vitro.

PLoS ONE, 2009
BackgroundMammalian cardiac myocytes withdraw from the cell cycle during post-natal development, resulting in a non-proliferating, fully differentiated adult phenotype that is unable to repair damage to the myocardium, such as occurs following a ...
Carmen H Coxon, Katrina A Bicknell, Fleur L Moseley, Gavin Brooks   +3 more
doaj   +1 more source

Investigating interactions between epicardial adipose tissue and cardiac myocytes: what can we learn from different approaches? [PDF]

, 2017
Heart disease is a major cause of morbidity and mortality throughout the world. Some cardiovascular conditions can be modulated by lifestyle factors such as increased exercise or a healthier diet, but many require surgical or pharmacological ...
Agra, Agra, Alexander, Alexander, Alexander, Alexopoulos, Arora, Baessler, Bakkum, Balcioglu, Berridge, Berry, Bers, Bers, Bełtowski, Bian, Burgeiro, Burridge, Castro, Chechi, Cheng, Chilukoti, Chiu, Daya, Dekker, Deng, Deng, Dobrzynski, Dong, Du, Eisner, Elie, Elisha, Engler, Fain, Fandino-Vaquero, Fernandez-Trasancos, Fosshaug, Frankel, Furuhashi, Gaborit, Gaborit, Gao, Georgiou, Ghantous, Gho, Goncalves, Greif, Greulich, Greulich, Greulich, Gruen, Guauque-Olarte, Haemers, Harada, Hassan, Hatem, Hatem, Hatem, Heijman, Heijman, Hua, Hung, Iacobellis, Iacobellis, Iacobellis, Iacobellis, Iacobellis, Iacobellis, Iacobellis, Imoto-Tsubakimoto, Iozzo, Itoh, Janik, Karastergiou, Kaushik, Kazumi, Kim, Kim, Kitagawa, Kleinz, Kusayama, Lage, Lamounier-Zepter, Lamounier-Zepter, Langheim, Leeper, Li, Lim, Lip, Look, MacQueen, Maghbooli, Mahabadi, Mahabadi, Marchington, Marchington, Margaritis, Martinsen, Matloch, Mattacks, Mattacks, Mattacks, Mazurek, Mazurek, Mazzoccoli, McAninch, Mookadam, Nakanishi, Nevelsteen, Nicholls, O'Connell, Pang, Paolisso, Parisi, Pezeshkian, Phillips, Pierdomenico, Pond, Pontes Soares, Prati, Rabkin, Rachwalik, Rainwater, Rajapurohitam, Rodriguez-Penas, Sacks, Sacks, Sacks, Sade, Salgado-Somoza, Samanta, Sarin, Scimia, Shapira-Schweitzer, Shibasaki, Shimabukuro, Siegel-Axel, Silaghi, Smith, Song do, Southan, Spiroglou, Szokodi, Takebayashi, Talman, Teijeira-Fernandez, Vacca, Venteclef, Viscogliosi, Voigt, Vural, Weikert, Westcott, White, Willens, Wong, Xu, Yamaguchi, Yañez-Rivera, Ye, Yilmaz, Zdychova, Zeng, Zhou   +164 more
core   +1 more source

Depletion of Ca2+ from the sarcoplasmic reticulum of cardiac muscle prompts phosphorylation of phospholamban to stimulate store refilling [PDF]

, 1998
Nonmuscle cells have almost ubiquitously evolved a mechanism to detect and prevent Ca(2+) store depletionstore operated calcium entry. No such mechanism has, as yet, been reported in cardiac myocytes.
Bhogal, M.S., Colyer, J.
core   +2 more sources

Unusual localization and translocation of TRPV4 protein in cultured ventricular myocytes of the neonatal rat

European Journal of Histochemistry, 2012
TRPV4 protein forms a Ca2+-permeable channel that is sensitive to osmotic and mechanical stimuli and responds to warm temperatures, and expresses widely in various kinds of tissues.
Y. Zhao, H. Huang, Y. Jiang, H. Wei, P. Liu, W. Wang, W. Niu   +6 more
doaj   +1 more source

Modeling effects of L-type ca(2+) current and na(+)-ca(2+) exchanger on ca(2+) trigger flux in rabbit myocytes with realistic T-tubule geometries. [PDF]

, 2012
The transverse tubular system of rabbit ventricular myocytes consists of cell membrane invaginations (t-tubules) that are essential for efficient cardiac excitation-contraction coupling. In this study, we investigate how t-tubule micro-anatomy, L-type Ca(
Andrew D McCulloch, Anushka Plamenova Michailova, Frank B Sachse, Frank B Sachse, J Andrew eMcCammon, Johan E Hake, Johan E Hake, John H Bridge, Michael J Holst, Peter M Kekenes-Huskey, Yuhui eCheng   +10 more
core   +2 more sources

PARM-1 is an endoplasmic reticulum molecule involved in endoplasmic reticulum stress-induced apoptosis in rat cardiac myocytes.

PLoS ONE, 2010
To identify novel transmembrane and secretory molecules expressed in cardiac myocytes, signal sequence trap screening was performed in rat neonatal cardiac myocytes.
Koji Isodono, Tomosaburo Takahashi, Hiroko Imoto, Naohiko Nakanishi, Takehiro Ogata, Satoshi Asada, Atsuo Adachi, Tomomi Ueyama, Hidemasa Oh, Hiroaki Matsubara   +9 more
doaj   +1 more source

Microtubule-Mediated Misregulation of Junctophilin-2 Underlies T-Tubule Disruptions and Calcium Mishandling in mdx Mice

JACC: Basic to Translational Science, 2016
Cardiac myocytes from the mdx mouse, the mouse model of Duchenne muscular dystrophy, exhibit t-tubule disarray and increased calcium sparks, but a unifying molecular mechanism has not been elucidated.
Kurt W. Prins, MD, PhD, Michelle L. Asp, PhD, Huiliang Zhang, PhD, Wang Wang, MD, PhD, Joseph M. Metzger, PhD   +4 more
doaj   +1 more source

De Novo Human Cardiac Myocytes for Medical Research: Promises and Challenges

Stem Cells International, 2017
The advent of cellular reprogramming technology has revolutionized biomedical research. De novo human cardiac myocytes can now be obtained from direct reprogramming of somatic cells (such as fibroblasts), from induced pluripotent stem cells (iPSCs, which
Veronique Hamel, Kang Cheng, Shudan Liao, Aizhu Lu, Yong Zheng, Yawen Chen, Yucai Xie, Wenbin Liang   +7 more
doaj   +1 more source

Pressure mediated hypertrophy and mechanical stretch up-regulate expression of the long form of leptin receptor (ob-Rb) in rat cardiac myocytes

BMC Cell Biology, 2012
Background Hyperleptinemia is known to participate in cardiac hypertrophy and hypertension, but the relationship between pressure overload and leptin is poorly understood. We therefore examined the expression of leptin (ob) and the leptin receptor (ob-R)
Matsui Hiroki, Yokoyama Tomoyuki, Tanaka Chie, Sunaga Hiroaki, Koitabashi Norimichi, Takizawa Takako, Arai Masashi, Kurabayashi Masahiko   +7 more
doaj   +1 more source