Results 11 to 20 of about 81,648 (268)
Hamartomas of mature cardiac myocytes [PDF]
European Heart Journal - Cardiovascular Imaging, 2008 We present two paediatric cases of a very rare, pathologically benign, and primary cardiac tumour composed of mature cardiac myocytes with disorganized cytoarchitecture called hamartoma of mature cardiac myocyte. The patients are usually asymptomatic, may have non-specific electrocardiogram findings, and rarely have associated sudden death.
Shaji C, Menon +3 more
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Nuclear Calcium in Cardiac Myocytes [PDF]
Journal of Cardiovascular Pharmacology, 2015 Calcium (Ca) is a universal second messenger involved in the regulation of various cellular processes, including electrical signaling, contraction, secretion, memory, gene transcription, and cell death. In heart, Ca governs cardiomyocyte contraction, is central in electrophysiological properties, and controls major signaling pathway implicated in gene ...
Ljubojevic, Senka, Bers, Donald M
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Calcium Signaling in Cardiac Myocytes [PDF]
Cold Spring Harbor Perspectives in Biology, 2011 Calcium (Ca(2+)) is a critical regulator of cardiac myocyte function. Principally, Ca(2+) is the link between the electrical signals that pervade the heart and contraction of the myocytes to propel blood. In addition, Ca(2+) controls numerous other myocyte activities, including gene transcription.
Fearnley, Claire J. +2 more
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Over expression of Plk1 does not induce cell division in rat cardiac myocytes in vitro.
PLoS ONE, 2009 BackgroundMammalian cardiac myocytes withdraw from the cell cycle during post-natal development, resulting in a non-proliferating, fully differentiated adult phenotype that is unable to repair damage to the myocardium, such as occurs following a ...
Carmen H Coxon +3 more
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European Journal of Histochemistry, 2012 TRPV4 protein forms a Ca2+-permeable channel that is sensitive to osmotic and mechanical stimuli and responds to warm temperatures, and expresses widely in various kinds of tissues.
Y. Zhao +6 more
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PLoS ONE, 2010 To identify novel transmembrane and secretory molecules expressed in cardiac myocytes, signal sequence trap screening was performed in rat neonatal cardiac myocytes.
Koji Isodono +9 more
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JACC: Basic to Translational Science, 2016 Cardiac myocytes from the mdx mouse, the mouse model of Duchenne muscular dystrophy, exhibit t-tubule disarray and increased calcium sparks, but a unifying molecular mechanism has not been elucidated.
Kurt W. Prins, MD, PhD +4 more
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De Novo Human Cardiac Myocytes for Medical Research: Promises and Challenges
Stem Cells International, 2017 The advent of cellular reprogramming technology has revolutionized biomedical research. De novo human cardiac myocytes can now be obtained from direct reprogramming of somatic cells (such as fibroblasts), from induced pluripotent stem cells (iPSCs, which
Veronique Hamel +7 more
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BMC Cell Biology, 2012 Background Hyperleptinemia is known to participate in cardiac hypertrophy and hypertension, but the relationship between pressure overload and leptin is poorly understood. We therefore examined the expression of leptin (ob) and the leptin receptor (ob-R)
Matsui Hiroki +7 more
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The Hippo pathway regulates density-dependent proliferation of iPSC-derived cardiac myocytes
Scientific Reports, 2021 Inducing cardiac myocytes to proliferate is considered a potential therapy to target heart disease, however, modulating cardiac myocyte proliferation has proven to be a technical challenge.
Abigail C. Neininger +3 more
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