Results 41 to 50 of about 81,648 (268)

Glial Growth Factor 2 Regulates Glucose Transport in Healthy Cardiac Myocytes and During Myocardial Infarction via an Akt-Dependent Pathway

Frontiers in Physiology, 2019
Neuregulin (NRG), a paracrine factor in myocytes, promotes cardiac development via the ErbB receptors. NRG-1β also improves cardiac function and cell survival after myocardial infarction (MI), although the mechanisms underlying these cardioprotective ...
Shanell Shoop, Shanell Shoop, Zahra Maria, Zahra Maria, Allison Campolo, Allison Campolo, Nabil Rashdan, Dominic Martin, Pamela Lovern, Véronique A. Lacombe, Véronique A. Lacombe, Véronique A. Lacombe   +11 more
doaj   +1 more source

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

Advanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng, Hainan Wu, Min Liu, Kunpeng Wu, Shuntao Huang, Zulfiqar Ahmed, Lenox Pius, Mengjin Zhu, Dequan Xu   +8 more
wiley   +1 more source

Overexpression of connexin 43 using a retroviral vector improves electrical coupling of skeletal myoblasts with cardiac myocytes in vitro

BMC Cardiovascular Disorders, 2006
Background Organ transplantation is presently often the only available option to repair a damaged heart. As heart donors are scarce, engineering of cardiac grafts from autologous skeletal myoblasts is a promising novel therapeutic strategy.
Kienast Yvonne, Ullrich Nina D, MacLeod Kenneth T, Spohr Hilmar, Patel Pravina, Themis Michael, Ma Yu-Ling, Tolmachov Oleg, Coutelle Charles, Peters Nicholas S   +9 more
doaj   +1 more source

Cardiac myocyte diversity and a fibroblast network in the junctional region of the zebrafish heart revealed by transmission and serial block-face scanning electron microscopy. [PDF]

PLoS ONE, 2013
The zebrafish has emerged as an important model of heart development and regeneration. While the structural characteristics of the developing and adult zebrafish ventricle have been previously studied, little attention has been paid to the nature of the ...
Pascal J Lafontant, Ali R Behzad, Evelyn Brown, Paul Landry, Norman Hu, Alan R Burns   +5 more
doaj   +1 more source

Gene transfer into cardiac myocytes in vivo [PDF]

Trends in Cardiovascular Medicine, 1991
The ability to express recombinant genes in cardiac myocytes in vivo holds promise for the treatment of a number of inherited and acquired diseases of the cardiovascular system. Several groups have demonstrated recently that plasmid DNA is taken up and expressed in cardiac myocytes following injection into the left ventricular wall in vivo. Recombinant
Leinwand, Leslie A., Leiden, Jeffrey M.
openaire   +3 more sources

A Correlative SICM‐OPM Platform for Surface and Volumetric Imaging in Live Cells

Advanced Science, EarlyView.
A multifunctional correlative imaging platform integrating Scanning Ion Conductance Microscopy (SICM) with Oblique Plane Microscopy (OPM) enables simultaneous surface topography, mechanical mapping, and 3D volumetric fluorescence imaging in live cells.
Wenzhi Hong, Ziwei Zhang, Ao Li, Ting Sun, Yunzhao Wu, Devkee M. Vadukul, Dylan Jones, Bing Li, Fengjie Liu, Francesco A. Aprile, Yuri Korchev, Julia Gorelik, David Klenerman, Andrew Shevchuk   +13 more
wiley   +1 more source

Incorporated fish oil fatty acids prevent action potential shortening induced by circulating fish oil fatty acids

Frontiers in Physiology, 2010
Increased consumption of fatty fish, rich in omega-3 polyunsaturated fatty acids (3-PUFAs) reduces the severity and number of arrhythmias. Long term 3-PUFA-intake modulates the activity of several cardiac ion channels leading to cardiac action ...
Hester M Den Ruijter, Arie O Verkerk, Ruben Coronel   +2 more
doaj   +1 more source

Characterizing Adrenergic Regulation of Glucose Transporter 4-Mediated Glucose Uptake and Metabolism in the Heart

JACC: Basic to Translational Science, 2023
Summary: Whereas adrenergic stimulation promotes cardiac function that demands more fuel and energy, how this receptor controls cardiac glucose metabolism is not defined.
Aleksandra Jovanovic, PhD, Bing Xu, BS, Chaoqun Zhu, PhD, Di Ren, PhD, Hao Wang, PhD, Meredith Krause-Hauch, PhD, E. Dale Abel, PhD, MD, Ji Li, PhD, Yang K. Xiang, PhD   +8 more
doaj   +1 more source

Cavity Microelectrode Arrays for Electrical Recordings From Neurons

Advanced Electronic Materials, EarlyView.
Microelectrode arrays (MEAs) are used to study electrophysiological activity. However, their signals are small with high noise. By adding a 100‐nanometer‐high cavity above the electrode, which reduces impedance without affecting resolution, we improve signal quality.
Johannes Lewen, Bernhard Wolfrum, Andreas Offenhäusser   +2 more
wiley   +1 more source

Cell Death in the Cardiac Myocyte

Biological & Pharmaceutical Bulletin, 2015
Loss of cardiac myocytes plays a critical role in the pathogenesis of cardiovascular disorders. A decrease in the number of cardiac myocytes in cardiac diseases results in sustained, irreversible contractile failure of myocardium. Therefore prevention of cardiac cell death is a potential therapeutic strategy for various heart diseases.
Marunouchi, Tetsuro, Tanonaka, Kouichi
openaire   +3 more sources