Results 11 to 20 of about 73,730 (199)
Epigenetic regulation of cardiac myocyte differentiation†[PDF]
Frontiers in Genetics, 2014 Cardiac myocytes (CMs) proliferate robustly during fetal life but withdraw permanently from the cell cycle soon after birth and undergo terminal differentiation. This cell cycle exit is associated with the upregulation of a host of adult cardiac-specific genes.
Danny El-Nachef +4 more
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Cellular Physiology of Rat Cardiac Myocytes in Cardiac Fibrosis: In Vitro Simulation Using the Cardiac Myocyte/Cardiac Non-Myocyte Co-Culture System [PDF]
Hypertension Research, 2008 An understanding of the cellular physiology of cardiac myocytes (MCs) and non-myocytes (NMCs) may help to explain the mechanisms underlying cardiac hypertrophy. Despite numerous studies using MC/NMC co-culture systems, it is difficult to precisely evaluate the influence of each cell type because of the inherent cellular heterogeneity of such a system ...
Chikara Otsubo +9 more
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MicroRNAs in a Cardiac Loop: Progenitor or Myocyte? [PDF]
Developmental Cell, 2010 Like transcription factors, microRNAs are emerging as regulators of cell fate decisions. In this issue, Wang et al. (2010) identify a critical microRNA pathway under the control of Bmp signaling that promotes outflow tract myocardial differentiation from cardiac progenitors in vivo.
Sylvia M. Evans +2 more
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Modeling the isolated cardiac myocyte
Progress in Biophysics and Molecular Biology, 2004 Computer modeling of cardiac myocytes has flourished in recent years. Models have evolved from mathematical descriptions of ionic channels alone to more sophisticated formulations that include calcium transport mechanisms, ATP production and metabolic pathways. The increased complexity is fueled by the new data available in the field.
Fei Wang +2 more
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Gene Transfer into Cardiac Myocytes [PDF]
, 2015 Traditional methods for DNA transfection are often inefficient and toxic for terminally differentiated cells, such as cardiac myocytes. Vector-based gene transfer is an efficient approach for introducing exogenous cDNA into these types of primary cell cultures.
Margaret V. Westfall, Sarah E. Lang
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Arrhythmogenic Transient Dynamics in Cardiac Myocytes [PDF]
Biophysical Journal, 2014 Cardiac action potential alternans and early afterdepolarizations (EADs) are linked to cardiac arrhythmias. Periodic action potentials (period 1) in healthy conditions bifurcate to other states such as period 2 or chaos when alternans or EADs occur in pathological conditions.
Xie, Yuanfang +3 more
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T-Tubule Function in Mammalian Cardiac Myocytes [PDF]
Circulation Research, 2003 The transverse tubules (t-tubules) of mammalian cardiac ventricular myocytes are invaginations of the surface membrane. Recent studies have suggested that the structure and function of the t-tubules are more complex than previously believed; in particular, many of the proteins involved in cellular Ca 2+ cycling ...
Brette, F, Orchard, CH
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Advanced Functional Materials, EarlyView.Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana +2 more
wiley +1 more source
Nanomaterials for Cardiac Myocyte Tissue Engineering [PDF]
Nanomaterials, 2016 Since their synthesizing introduction to the research community, nanomaterials have infiltrated almost every corner of science and engineering. Over the last decade, one such field has begun to look at using nanomaterials for beneficial applications in tissue engineering, specifically, cardiac tissue engineering. During a myocardial infarction, part of
Rodolfo Amezcua +4 more
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Frequency-dependent signaling in cardiac myocytes
Frontiers in Physiology, 2022 Background: Recent experimental data support the view that signaling activity at the membrane depends on its geometric parameters such as surface area and curvature. However, a mathematical, biophysical concept linking shape to receptor signaling is missing.
Payam Haftbaradaran Esfahani +4 more
openaire +3 more sources