Active Movement of the Tunic in Halocynthia roretzi
Halocynthia roretzi, a solitary ascidian, can swell and deflate its solid, leather-like tunic largely, but it is not clear whether the tunic deforms actively.
Yoko KATO
doaj +1 more source
Early pathohistological changes in dysfunction of arteriovenous fistula for hemodialysis [PDF]
Background. In hemodialysis patients the most common cause of vascular access failure is neointimal hyperplasia of vascular smooth muscle cells at the venous anastomosis of arteriovenous fistulas. Case report.
Stolić Radojica +3 more
doaj +1 more source
Kv7 and Kv11 channels in myometrial regulation.
Ion channels play a key role in defining myometrial contractility. Modulation of ion channel populations is proposed to underpin gestational changes in uterine contractility associated with the transition from uterine quiescence to active labour.
Tribe, Rachel M; id_orcid +5 more
core +1 more source
Cromakalim (BRL 34915) restores in vitro the membrane potential of depolarized human skeletal muscle fibres [PDF]
The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as K+ channel openers, on the electrical activity of human skeletal muscle.
Lehmann-Horn, Frank +2 more
core +1 more source
Mechanisms of Pericyte‐Mediated Cancer Metastasis
Pericytes play multifarious roles in promoting cancer metastasis by facilitating metastatic cancer cell dissemination, circulating tumor cell survival, tissue extravasation, premetastatic niche formation, and metastatic tumor growth. These cells have intertwined interactions with vascular endothelial cells to modulate cancer cell behavior and ...
Ziheng Guo, Yihai Cao
wiley +1 more source
Evidence For Phosphorylation-Dependent Modulation of BK Channel Activity in Vascular Smooth Muscle (VSM) Myocytes and Resistance Arteries [PDF]
VSM excitability is regulated by large conductance, calcium-activated K+ (BK) channels. We have previously reported that type I cGMP-dependent protein kinase (cGKI) phosphorylates the BK channel at key serine residues, leading to augmented BK current magnitude. Here, we investigate the cellular mechanisms regulating the temporal pattern (i.e. onset and
Kyle, Barry D. +2 more
openaire +1 more source
Poor spontaneous and oxytocin-stimulated contractility in human myometrium from postdates pregnancies [PDF]
Prolongation of pregnancy i.e. going more than 10 days over the estimated due date, complicates up to 10% of all pregnancies and is associated with increased risk to both mother and fetus.
Arrowsmith Sarah +14 more
core +1 more source
ABSTRACT Human atrial chambers derive from distinct embryonic anlagens, the original embryonic atria gradually transforming into the so‐called auricles, or atrial appendages. This study quantifies macroscopic variations in pectinate muscle architecture in human atrial appendages and evaluates their visualization using clinical imaging modalities.
Markéta Lexová +11 more
wiley +1 more source
Cardiac remodeling and arrhythmia in a mouse model of Depdc5 haploinsufficiency
Abstract Objective Some ion channel genes linked to developmental and epileptic encephalopathy (DEE) are also linked to cardiac arrhythmia, leading to the hypothesis that predisposition to cardiac arrhythmias may contribute to the complex disease presentation of DEE and possibly to the mechanism of sudden unexpected death in epilepsy.
Roberto Ramos‐Mondragon +9 more
wiley +1 more source
Multiple P2Y receptors couple to calcium-dependent, chloride channels in smooth muscle cells of the rat pulmonary artery [PDF]
Uridine 5'-triphosphate (UTP) and uridine 5'-diphosphate (UDP) act via P2Y receptors to evoke contraction of rat pulmonary arteries, whilst adenosine 5'-triphosphate (ATP) acts via P2X and P2Y receptors.
Chootip, Krongkarn +9 more
core +1 more source

