Results 121 to 130 of about 37,117 (236)
ABSTRACT Background Patients with end‐stage liver disease (ESLD) often present with sarcopenia, defined as loss of skeletal muscle mass and quality, which is associated with reduced quality of life and increased mortality. However, the molecular mechanisms driving sarcopenia in ESLD are not fully understood and there are currently no therapeutic ...
Thomas Nicholson +16 more
wiley +1 more source
Understanding the regulation of skeletal muscle development is important to meet the increasing demand of Indian major carp Labeo rohita. Myogenic regulatory factors (MRFs) along with myocyte specific enhancer factor 2 (MEF2) play the pivotal role in the
Archya Sengupta +4 more
doaj +1 more source
ABSTRACT Background Cancer cachexia is a debilitating syndrome characterized by severe skeletal muscle wasting, which significantly impairs patient quality of life and survival. Indoleamine 2,3‐dioxygenase 1 (IDO1), a key enzyme in tryptophan (Trp) metabolism, is often upregulated in cancers, but its specific role in driving lung cancer–associated ...
Leng Han +12 more
wiley +1 more source
What determines growth potential and juvenile quality of farmed fish species? [PDF]
Enhanced production of high quality and healthy fry is a key target for a successful and competitive expansion of the aquaculture industry. Although large quantities of fish larvae are produced, survival rates are often low or highly variable and growth ...
Alami-Durante +225 more
core +3 more sources
The SNPs in myoD gene from normal muscle developing individuals have no effect on muscle mass
Background Myogenic Differentiation 1 (MyoD) is a crucial master switch in regulating muscle-specific gene transcription. Forced expression of myoD is equipped to induce several cell lineages into myoblast, which then differentiate and fuse into myotube.
Suying Ding +11 more
doaj +1 more source
Coordinated actions of microRNAs with other epigenetic factors regulate skeletal muscle development and adaptation [PDF]
Epigenetics plays a pivotal role in regulating gene expression in development, in response to cellular stress or in disease states, in virtually all cell types.
Adamo, Sergio +3 more
core +1 more source
Myodes californicus Merriam 1890
47. Western Red-backed Vole Myodes californicus French: Campagnol de Merriam / German: Westliche Rotelmaus / Spanish: Topillo rojo de California Other common names: California Red-backed Vole Taxonomy. Myodes californicus Merriam, 1890, Eureka, Humboldt County, California, USA. Three subspecies are recognized. Subspecies and Distribution.
Don E. Wilson +2 more
openaire +2 more sources
Ageing‐Associated Dysregulation of Myogenic Differentiation in Inclusion Body Myositis
ABSTRACT Skeletal muscle is a postmitotic tissue dependent on a complex and tightly regulated regeneration process involving numerous intracellular and extracellular factors, including myogenic regulatory factors (MRFs), cytokines and myokines. Quiescent satellite cells are activated by physiological stimuli, injury or other traumatic insults for the ...
Geert M. de Vries +2 more
wiley +1 more source
ATP citrate lyase (ACL) plays a key role in regulating mitochondrial function, as well as glucose and lipid metabolism in skeletal muscle. We report here that ACL silencing impairs myoblast and satellite cell (SC) differentiation, and it is accompanied ...
Suman Das +10 more
doaj +1 more source
Heme Metabolism‐Derived Carbon Monoxide Regulates Skeletal Muscle Function
ABSTRACT Background Heme oxygenases, HO‐1 (Hmox1) and HO‐2 (Hmox2), regulate skeletal muscle homeostasis by degrading heme and generating carbon monoxide (CO), a bioactive signalling molecule. Although HO‐1 is known to influence muscle fibre composition and mitochondrial function, the role of HO‐2 in activity‐dependent neuromuscular plasticity remains ...
Rodrigo W. Alves de Souza +8 more
wiley +1 more source

