Results 111 to 120 of about 37,117 (236)

Functional validation and expression analysis of myotubes converted from skin fibroblasts using a simple direct reprogramming strategy

open access: yeseNeurologicalSci, 2017
Previously, we reported that MyoD, a master gene for myogenic cells, could efficiently convert primary skin fibroblasts into myoblasts and myotubes, thereby effecting direct reprogramming.
Fukuko Horio   +5 more
doaj   +1 more source

The mechanical stimulation of myotubes counteracts the effects of tumor-derived factors through the modulation of the activin/follistatin ratio [PDF]

open access: yes, 2019
Activin negatively affects muscle fibers and progenitor cells in aging (sarcopenia) and in chronic diseases characterized by severe muscle wasting (cachexia). High circulating activin levels predict poor survival in cancer patients. However, the relative
Adamo, Sergio   +8 more
core   +2 more sources

Restoration of neuromuscular function by mitochondrial transplantation in injured mouse skeletal muscle

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Mice received chemical injury (cardiotoxin) in the tibialis anterior muscle of one limb, and the contralateral muscle was injected with phosphate‐buffered saline (PBS) as a sham control. Mice then received PBS or mitochondria suspended in PBS into the tail vein.
Stephen E. Alway   +6 more
wiley   +1 more source

Prmt5 is a regulator of muscle stem cell expansion in adult mice. [PDF]

open access: yes, 2015
Skeletal muscle stem cells (MuSC), also called satellite cells, are indispensable for maintenance and regeneration of adult skeletal muscles. Yet, a comprehensive picture of the regulatory events controlling the fate of MuSC is missing.
Braun, Thomas   +7 more
core  

Accumulation of muscle ankyrin repeat protein transcript reveals local activation of primary myotube endcompartments during muscle morphogenesis [PDF]

open access: yes, 1997
The characteristic shapes and positions of each individual body muscle are established during the process of muscle morphogenesis in response to patterning information from the surrounding mesenchyme. Throughout muscle morphogenesis, primary myotubes are
Adams   +37 more
core   +1 more source

Embryonal Paratesticular Rhabdomyosarcoma Masquerading as an Inguinal Hernia: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Embryonal paratesticular rhabdomyosarcoma can mimic benign inguinoscrotal conditions such as inguinal hernia. In children with persistent, painless scrotal masses, early cross‐sectional imaging and prompt radical inguinal orchiectomy with histopathological confirmation are essential.
Somaya Al Kiswani   +7 more
wiley   +1 more source

Effect of Acute Aerobic Physical Activity on Skeletal Muscle MyoD Gene Expression of Wistar Rats

open access: yesMajalah Kedokteran Bandung, 2019
Aerobic physical activity is known to induce skeletal muscle adaptation. Some genes, including MyoD, are known to have a major role in the process of muscle adaptation.
Setiawan Setiawan   +5 more
doaj   +1 more source

Targeting RyR Activity Boosts Antisense Exon 44 and 45 Skipping in Human DMD Skeletal or Cardiac Muscle Culture Models. [PDF]

open access: yes, 2019
Systemic delivery of antisense oligonucleotides (AO) for DMD exon skipping has proven effective for reframing DMD mRNA, rescuing dystrophin expression, and slowing disease progression in animal models.
Barthélémy, Florian   +6 more
core   +1 more source

Biomaterial Physical Cues as Gene Regulators for Cellular Agriculture

open access: yesAdvanced Genetics, Volume 7, Issue 2, June 2026.
This review elucidates how biomaterial physical cues—ranging from matrix stiffness to remote electromagnetic fields—serve as extrinsic regulators of gene expression in cellular agriculture. By identifying central mechanotransduction pathways that bridge physical inputs to genetic remodeling, the authors propose the “Material Genome” concept: a ...
Jianuo Liu, Ye Liu
wiley   +1 more source

Loss of MyoD and Myf5 in Skeletal Muscle Stem Cells Results in Altered Myogenic Programming and Failed Regeneration

open access: yesStem Cell Reports, 2018
Summary: MyoD and Myf5 are fundamental regulators of skeletal muscle lineage determination in the embryo, and their expression is induced in satellite cells following muscle injury.
Masakazu Yamamoto   +7 more
doaj   +1 more source

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