Results 51 to 60 of about 27,684 (229)

Effects of insulin like growth factors on early embryonic chick limb myogenesis. [PDF]

PLoS ONE, 2017
Limb muscles derive from pax3 expressing precursor cells that migrate from the hypaxial somite into the developing limb bud. Once there they begin to differentiate and express muscle determination genes such as MyoD.
Rabeea Hazim Mohammed, Helen Anderton, John Michael Brameld, Dylan Sweetman   +3 more
doaj   +1 more source

Cis-regulatory determinants of MyoD function [PDF]

Nucleic Acids Research, 2018
Muscle-specific transcription factor MyoD orchestrates the myogenic gene expression program by binding to short DNA motifs called E-boxes within myogenic cis-regulatory elements (CREs). Genome-wide analyses of MyoD cistrome by chromatin immnunoprecipitation sequencing shows that MyoD-bound CREs contain multiple E-boxes of various sequences.
Soleimani, Vahab D, Nguyen, Duy, Ramachandran, Parameswaran, Palidwor, Gareth A, Porter, Christopher J, Yin, Hang, Perkins, Theodore J, Rudnicki, Michael A   +7 more
openaire   +2 more sources

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

Advanced Materials, EarlyView.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung, Minjun Kim, Da‐Yoon Kim, Min Kyu Kim, Sieun Lee, Yoonhee Jin, Joo H. Kang   +6 more
wiley   +1 more source

miRNA-223 upregulated by MYOD inhibits myoblast proliferation by repressing IGF2 and facilitates myoblast differentiation by inhibiting ZEB1

Cell Death and Disease, 2017
Skeletal muscle differentiation can be regulated by various transcription factors and non-coding RNAs. In our previous work, miR-223 is differentially expressed in the skeletal muscle of chicken with different growth rates, but its role, expression and ...
Guihuan Li, W. Luo, B. A. Abdalla, H. Ouyang, Jiao Yu, Fan Hu, Q. Nie, Xiquan Zhang   +7 more
semanticscholar   +1 more source

Myodes rutilus

, 2017
Published as part of Don E. Wilson, Russell A. Mittermeier & Thomas E. Lacher, Jr, 2017, Cricetidae, pp. 204-535 in Handbook of the Mammals of the World – Volume 7 Rodents II, Barcelona :Lynx Edicions on pages 303-304, DOI: 10.5281/zenodo ...
Don E. Wilson, Russell A. Mittermeier, Thomas E. Lacher, Jr   +2 more
openaire   +2 more sources

MyoD Is a Tumor Suppressor Gene in Medulloblastoma [PDF]

Cancer Research, 2013
Abstract While medulloblastoma, a pediatric tumor of the cerebellum, is characterized by aberrations in developmental pathways, the majority of genetic determinants remain unknown. An unbiased Sleeping Beauty transposon screen revealed MyoD as a putative medulloblastoma tumor suppressor.
Joyoti, Dey, Adrian M, Dubuc, Kyle D, Pedro, Derek, Thirstrup, Brig, Mecham, Paul A, Northcott, Xiaochong, Wu, David, Shih, Stephen J, Tapscott, Michael, LeBlanc, Michael D, Taylor, James M, Olson   +11 more
openaire   +2 more sources

Mesenchymal Stromal Cell‐Mediated Intercellular Communication: Mapping the Interactome for Skeletal Muscle Homeostasis and Regeneration

Advanced Science, EarlyView.
Liu et al. define a systems‐level interactome of fibroadipogenic progenitor (FAP)‐mediated signaling in skeletal muscle by integrating single‐cell transcriptomics with FAP depletion‐based perturbation analysis. Functional interrogation using a conditioned media bioassay links predicted signaling to multicellular outcomes, establishing a framework to ...
Xingyu Liu, Edgar E. Perez Carbajal, Yih‐Chii Hwang, Sahil A. Mapkar, Benjamin W. Gilman, Sarah A. Bliss, Lam B. Tran, Kalgi T. Mehta, Jacob O. Banyasz, Ming Yu, Reynold R. Liu, Matthew N. Ly, Christapher S. Morrissey, Michael N. Wosczyna   +13 more
wiley   +1 more source

Myodes rutilus

, 2005
Myodes rutilus (Pallas 1779) [Mus] rutilus Pallas 1779, Nova Spec. Quad. Glir. Ord.: 246. Type Locality: Russia, Siberia, center of Ob River delta. Vernacular Names: Northern Red-backed Vole. Synonyms: Myodes alascensis (Miller 1898); Myodes albiventer (Hall and Gilmore 1932); Myodes amurensis (Schrenk 1859); Myodes baikalensis (Ognev 1924); Myodes ...
Wilson, Don E., Reeder, DeeAnn
openaire   +2 more sources

Fine‐Tuned Regulation of mRNA Translation and Transport by STAU2 Condensate Facilitates Neuronal Development and Plasticity

Advanced Science, EarlyView.
STAU2 undergoes phase separation to form dynamic condensates that package target mRNAs and deliver them to the distal ends of growing neuronal dendrites. STAU2 condensates stabilize embedded mRNAs and repress their translation. Synaptic activity bidirectionally remodels STAU2 condensates, coordinating local translation of STAU2‐associated mRNAs ...
Shijing Huang, Yuanyuan Chu, Ruiqian Zhao, Siyu Li, Yu Feng, Hongdan Zheng, Yunli Xie, Tong Wang, Wenyu Wen   +8 more
wiley   +1 more source

The effect of acid sphingomyelinase inhibitor on oxidative stress, advance glycation end products and myosin phenotype of rat soleus muscle under conditions of functional unloading

Acta Biomedica Scientifica
Introduction. Functional unloading of  muscles is  accompanied by  slow-to-fast transformation of muscle myosin phenotype, an increase in acid sphingomyelinase (ASM) activity, ceramide, reactive oxygen species (ROS), and  advanced glycation end products (
V. A. Protopopov, A. V. Sekunov, A. M. Mugizov, I. V. Svidersky, I. G. Bryndina   +4 more
doaj   +1 more source