Results 1 to 10 of about 59,231 (244)
Inflammatory myofibroblastic tumor
Contemporary Clinical Dentistry, 2011 Inflammatory myofibroblastic tumor is an uncommon lesion of unknown cause. It encompasses a spectrum of myofibroblastic proliferation along with varying amount of inflammatory infiltrate.
Sangeeta Palaskar +3 more
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Extracellular PKM2 facilitates organ-tissue fibrosis progression
iScience, 2021 Summary: Persistent activation of fibroblasts and resistance of myofibroblasts to turnover play important roles in organ-tissue fibrosis development and progression.
Hongwei Han +7 more
doaj +1 more source
Current Opinion in Rheumatology, 2013 Interest in the myofibroblast as a key player in propagation of chronic progressive fibrosis continues to elicit many publications, with focus on its cellular origins and the mechanisms underpinning their differentiation and/or transition. The objective of the review is to highlight this recent progress.The epithelial origin of the myofibroblast in ...
Biao, Hu, Sem H, Phan
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Myofibroblasts. II. Intestinal subepithelial myofibroblasts [PDF]
American Journal of Physiology-Cell Physiology, 1999 Intestinal subepithelial myofibroblasts (ISEMF) and the interstitial cells of Cajal are the two types of myofibroblasts identified in the intestine. Intestinal myofibroblasts are activated and proliferate in response to various growth factors, particularly the platelet-derived growth factor (PDGF) family, which includes PDGF-BB and stem cell factor ...
D W, Powell +5 more
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Editorial: Liver Myofibroblasts [PDF]
Frontiers in Physiology, 2016 Myofibroblasts (MFB) were first identified in the granulation tissue of healing wounds. They have features of both fibroblasts and smooth muscle cells. In contrast to fibroblasts they contain cytoplasmic actin microfilaments (stress fibers) connected to the extracellular matrix (ECM) by focal contacts.
Kanta, Jiri +2 more
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Scientific Reports, 2021 Myofibroblasts are the key effector cells responsible for the exaggerated tissue fibrosis in Systemic Sclerosis (SSc). Despite their importance to SSc pathogenesis, the specific transcriptome of SSc myofibroblasts has not been described.
Giuseppina Abignano +5 more
doaj +1 more source
Comparison of Myofibroblasts Between Solid/Multicystic Ameloblastoma and Unicystic Ameloblastoma: An Immunohistochemical Analysis [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: Microenvironment is crucial for the maintenance of cellular functions and tissue integrity suggesting that cancer-induced changes in the stroma may contribute to cancer invasion and its biological behaviour. One of the major constituent
Gowdara Prakash Smitha +3 more
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Evaluation of Myofibroblasts by Expression of Alpha Smooth Muscle Actin: A Marker in Fibrosis, Dysplasia and Carcinoma [PDF]
Journal of Clinical and Diagnostic Research, 2014 Objective: Evaluation of Myofibroblasts by studying expression of Alpha smooth muscle actin: A marker of Fibrosis, Dysplasia and Carcinoma. Background: Myofibroblasts are cells that have contractile properties and are involved in inflammation, wound ...
Bharath Rao K +3 more
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Targeted apoptosis of myofibroblasts by elesclomol inhibits hypertrophic scar formation
EBioMedicine, 2020 Background: Hypertrophic scar (HS) is characterized by the increased proliferation and decreased apoptosis of myofibroblasts. Myofibroblasts, the main effector cells for dermal fibrosis, develop from normal fibroblasts.
Yi Feng +8 more
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Human liver myofibroblasts during development and diseases with a focus on portal (myo)fibroblasts.
Frontiers in Physiology, 2015 Myofibroblasts are stromal cells mainly involved in tissue repair. These cells present contractile properties and play a major role in extracellular matrix deposition and remodeling. In liver, myofibroblasts are found in two critical situations.
Sébastien eLepreux +1 more
doaj +1 more source