Results 201 to 210 of about 94,921 (285)

Gastrointestinal strictures in a pediatric patient with Satoyoshi syndrome

JPGN Reports, EarlyView.
Abstract We present a novel case of gastrointestinal strictures in a young girl with Satoyoshi syndrome (SS), highlighting multi‐system features of alopecia universalis, painful muscle cramps with dystonia, aberrant growth velocity, and skeletal abnormalities.
Katherine (Tusia) Pohoreski, Gary Galante, Kiera Pajunen, Marie‐Anne Brundler, Samarjeet Bhandal, Iwona Wrobel   +5 more
wiley   +1 more source

The Role of Fibrosis in Androgenetic Alopecia: Mechanisms and Implications. [PDF]

Skin Appendage Disord
Li L, Chen Y, Lin M, Chen T, Xi Y, Fan Y, Ding X.   +6 more
europepmc   +1 more source

Increased pulmonary blood flow leads to alveolar dysplasia during the early postnatal developmental stage. [PDF]

Cell Biosci
Zhang H, Zheng S, Wang Z, Xiao Y, Hu Y, Li D, Cui Q, Liu C, Xue Y, Wu J, Sun S, Ye L.   +11 more
europepmc   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Correction: Single-cell and spatial profiling highlights TB-induced myofibroblasts as drivers of lung pathology. [PDF]

J Exp Med
Mbano IM, Liu N, Wadsworth MH, Chambers MJ, Mpotje T, Asowata OE, Nyquist SK, Nargan K, Ramsuran D, Karim F, Hughes TK, Bromley JD, Krause R, Naidoo T, Tezera LB, Reichmann MT, Ganchua SK, Kløverpris HN, Dullabh KJ, Madansein R, Triana S, Steyn AJC, Berger B, Marakalala MJ, Pollara G, Fortune SM, Flynn JL, Elkington PT, Shalek AK, Leslie A.   +29 more
europepmc   +1 more source

Senescent Mesenchymal Stromal Cells Differentially Alter Adipogenesis in Adipose Tissue, Skeletal Muscle, and Bone Marrow

Obesity, EarlyView.
ABSTRACT Objective Aging alters mesenchymal stromal cell (MSC) function, leading to dysregulated adipogenesis across tissues through biased lineage commitment. Fat redistribution from adipose depots to skeletal muscle and bone marrow is common in aging, but the underlying mechanisms remain unclear.
Xu Zhang, Madison L. Doolittle, Ting Fan, Utkarsh Tripathi, Yan Er Ng, Xinyi Jiang, João F. Passos, Diana Jurk, David G. Monroe, Tamara Tchkonia, James L. Kirkland, Paul D. Robbins, Sundeep Khosla, Nathan K. LeBrasseur   +13 more
wiley   +1 more source

Alcohol-related hepatitis induces a specific fibrosis profile through YAP activation in myofibroblasts. [PDF]

JHEP Rep
Wandji LCN, Bou Saleh M, Sobolewski C, El Amrani M, Bray F, Boleslawski E, Eeckhoute J, Devaux PJ, Maggiotto F, Taront S, Rolando C, Gnemmi V, Mathurin P, Dubuquoy L, Louvet A.   +14 more
europepmc   +1 more source

Crohn's lymphoid aggregates with endothelial clusters colocalise with submucosal fibrosis in fibrostenosing Crohn's disease

The Journal of Pathology, EarlyView.
Abstract Crohn's disease (CD) involves chronic transmural inflammation of the intestines, leading to progressive wall fibrosis with stenosis and luminal obstruction, predominantly in the terminal ileum. Fibrosis is a significant therapeutic challenge, thus improved understanding of localisation, cellular composition, and cell–cell interactions in CD ...
Michael Glinka, Gregory J Wickham, Francesca Nadalin, Kathryn J Kirkwood, Helen Caldwell, Mike Wicks, Bill Hill, Derek Houghton, Mehran Sharghi, Amirhosein Kefayat, Bernard Haggarty, Albert Burger, Richard A Baldock, David J Adams, Irene Papatheodorou, Peter Bankhead, Shahida Din, Mark J Arends   +17 more
wiley   +1 more source

Engineered T cell therapy for the treatment of cardiac fibrosis during chronic phase of myocarditis. [PDF]

Theranostics
Hua X, Sun Z, Liang Z, Huang Y, Mo H, Dong F, Mo S, Yang X, Zhang N, Chen X, Liao S, Qi Z, Zhang R, Guan S, Li L, Xu Y, Song J.   +16 more
europepmc   +1 more source

Uncoupling TGFβ1 signalling from collagen protein synthesis in Dupuytren's disease

The Journal of Pathology, EarlyView.
Abstract Dupuytren's disease is a fibroproliferative disorder of the palmer fascia (PF) characterised by flexion contractures in the hand. Dupuytren's disease can be treated surgically, but disease recurrence rates are high, potentially due to continual production of matrisomal proteins.
Gabriella Cooper, Jade A Gumbs, Sahem Alkharabsheh, Katie J Lee, Alan Carter, Hannah Coleman, Niamh S O'Heneghan‐Yates, Rama Ijaz, Emma Beamish, Lisa A Menezes, Triantafillos Liloglou, Peter D Clegg, Elizabeth G. Canty‐Laird   +12 more
wiley   +1 more source