Results 71 to 80 of about 73,741 (198)
Arquivos Brasileiros de Cardiologia, 1999 OBJECTIVE: To study the healing process of the myocardium in hypertensive rats undergoing inhibition of nitric oxide synthesis. METHODS: Two groups of animals were studied: one received L-NAME, 12mg/kg/day, and the other was a control group. The presence
Mônica Gomes Pessanha +2 more
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PIEZO1 mediates periostin+ myofibroblast activation and pulmonary fibrosis in mice
The Journal of Clinical InvestigationIdiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease characterized by the excessive accumulation of activated myofibroblasts that deposit extracellular matrix (ECM) protein, leading to progressive scar formation and mechanical ...
Liran Xu +22 more
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Myofibroblasts: Master of disguise
Journal of Oral and Maxillofacial Pathology, 2017 Myofibroblasts are the unique population of smooth muscle-like fibroblasts. These cells have a role in growth factors secretion, matrix deposition and degradation. Thereby, myofibroblast contributes in both human physiology and pathology. This review explains the myofibroblastic lesions, imperative role of myofibroblasts in organogenesis, repair ...
Bagalad, Bhavana S +2 more
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Increased release of serotonin from rat primary isolated adult cardiac myofibroblasts
, 2021 Elevated blood serotonin levels have been observed in patients with heart failure and serotonin has a role in pathological cardiac function. The serotonin receptor system was examined in adult rat isolated cardiac fibroblast and myofibroblast cells. This
Emiri Tarbit +9 more
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Frontiers in PhysiologyWe propose that the key initiators of renal fibrosis are myofibroblasts which originate from four predominant sources—fibroblasts, pericytes, endothelial cells and macrophages.
Rashida Lathan
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Angiogenic properties of myofibroblasts isolated from normal human skin wounds
, 2012 During wound healing, angiogenesis plays a crucial role in inducing adequate perfusion of the new tissue, thereby allowing its survival. This angiogenic process contributes to the formation of granulation tissue, alongside myofibroblasts.
Roy, Michel +6 more
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Biology of Fibroblasts and Myofibroblasts [PDF]
Proceedings of the American Thoracic Society, 2008 Abstract Despite their importance in fibrosis, the origin of fibroblasts and the genesis of the various subpopulations characterized by distinct phenotypes remain unclear. Various studies have described distinct and relatively stable phenotypes in fibroblasts isolated from lung tissue undergoing remodeling, which were not present in ...
openaire +2 more sources
Research Progress of Pericytes in Pulmonary Fibrosis
Frontiers in Bioscience-LandmarkPericytes, a specific type of mesenchymal cell that surround the basement membrane of pulmonary venules and capillaries. They are crucial pathological features observed in individuals with the severe lung disease of pulmonary fibrosis (PF).
Xiaobo He +5 more
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IL-33/ST2 Axis in Organ Fibrosis
Frontiers in Immunology, 2018 Interleukin 33 (IL-33) is highly expressed in barrier sites, acting via the suppression of tumorigenicity 2 receptor (ST2). IL-33/ST2 axis has long been known to play a pivotal role in immunity and cell homeostasis by promoting wound healing and tissue ...
Ourania S. Kotsiou +4 more
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The role of myofibrolasts in normal skin wound healing
, 2016 Cutaneous myofibroblasts are cells that appear during normal wound healing when the wounded area requiring repair is significant. These cells differentiate from fibroblasts and, for many years, it was believed that their only role was to facilitate wound
Moulin, Véronique
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