Results 141 to 150 of about 814,354 (242)

Engineering In Vitro Models of Skeletal Muscle With Neuromuscular Junctions Using Hierarchical Micro‐Nano Biomaterials: Cooperative Effect of Adhesion Ligand Nanoclustering and Surface Anisotropy

Small, EarlyView.
This study investigates the cooperative effects of adhesive ligand distribution, density, and biomaterial morphology for innervated skeletal muscle tissue engineering. Ligand nanoclusters were created in aligned micropatterns by electrospinning of a RAFT‐synthesized polymer with controlled ligand presentation.
Shirin Nour, Kristy Swiderski, Sahar Salehi, Gordon S. Lynch, Andrea J. O'Connor, Greg G. Qiao, Daniel E. Heath   +6 more
wiley   +1 more source

Unveiling Otolith Mystery: Contemporary Testing Approaches and Their Clinical Significance

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Otolith is a critical component of the peripheral vestibular system responsible for detecting linear acceleration. Dysfunction of the otolith organs can lead to vertigo, balance disturbances, and gaze instability. By elucidating the physiological foundations and evaluating both current and emerging methods for assessing otolith ...
Shun Zhou, E Tian, Hua‐Jing Yang, Jun Wang, Zhao‐Qi Guo, Jing‐Yu Chen, Wan‐Di Xu, Jia‐Qi Guo, Zhang‐Hong Zhou, Shi‐Yu Shi, Xi‐Xi Yu, Xin‐Bo Gao, Ni Zhai, Xin Ma, Qing Zhang, Yi‐Sheng Lu, Su‐Lin Zhang   +16 more
wiley   +1 more source

Calcitonin‐like diuretic hormone influences reproduction in adult female Rhodnius prolixus

Insect Science, EarlyView.
Highlights • CT/DH‐like immunoreactivity is present in female reproductive tissues • CT/DH receptor transcripts are expressed in the fat body and ovaries • RNAi knockdown of CT/DH receptors reduces egg number and hatching rate • Rhopr‐CT/DH increases RhoprVg1 and RhoprVgR expression in ovaries in vitro • Rhopr‐CT/DH stimulates oviduct contractions in a
Areej N. Al‐Dailami, Ian Orchard, Angela B. Lange   +2 more
wiley   +1 more source

Overexpression of syndecan-4 inhibits myogenesis by regulating the expression of myogenic regulatory factors

Journal of Animal Science and Technology
Syndecan-4, a type of heparin sulfate proteoglycan, plays an important role in muscle development, regeneration, and maintenance. Although, the important effects of syndecan-4 on the regulation of myogenesis in mice, turkeys, and bovines have been ...
Sarang Choi, Jeong-Woong Park, Sang In Lee, Sangsu Shin   +3 more
doaj   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

The Role of Emerin in Myogenic Differentiation

The nucleus harbors genetic material encapsulated by the nuclear envelope which is composed of an inner and outer nuclear membrane. The establishment and organization of chromatin at the INM is essential for cell fate during the differentiation program ...
Marano, Nicholas
core   +1 more source

Vitamin C is essential for proper myogenic differentiation

Archives of Biochemistry and Biophysics
Vitamin C (VC) is naturally present in the blood and skeletal muscles. However, conventional myoblast culture media typically lack VC. Because VC exists in skeletal muscle, VC-supplemented media should better represent physiological conditions than VC-deficient media.
Yoshitaka Kondo, Ayami Sato, Noritsugu Osakabe, Tatsuki Minowa, Yung-Li Hung, Shuichi Machida, Akihito Ishigami   +6 more
openaire   +2 more sources

Static Otolith Signals Reflect Clinical Course in Acute Vestibular Neuritis

Clinical Otolaryngology, EarlyView.
ABSTRACT Objectives To investigate how static and dynamic utricular functions differentially correlate with dizziness symptoms and quality of life (QoL) recovery in patients with acute vestibular neuritis (VN). Design Prospective observational study with 1‐week and 1‐month follow‐up assessments. Setting Tertiary referral centre. Participants Twenty‐six
Seo‐Young Choi, Jae‐Hwan Choi, Hyun Sung Kim, Kwang‐Dong Choi   +3 more
wiley   +1 more source

Nocturnal Hypoxemia Burden Correlates With Vestibular Dysfunction in Obstructive Sleep Apnea

Clinical Otolaryngology, EarlyView.
ABSTRACT Introduction Obstructive sleep apnea (OSA) is a potential contributor to vestibular dysfunction, though specific correlating parameters remain unclear. This study aimed to determine whether hypoxemia severity indices correlate quantitatively with caloric slow‐phase eye velocity (SPV), a marker of vestibular function. Methods In a retrospective
Dachan Kim, Seong Hoon Bae, Hyung‐Ju Cho   +2 more
wiley   +1 more source

Enhanced Media Optimize Bovine Myogenesis in 2D and 3D Models for Cultivated Meat Applications

Advanced Science
Livestock farming and conventional meat production pose significant environmental, health, and animal welfare challenges. In seeking sustainable alternative solutions, cultivated meat technology typically utilizes differentiation of myogenic progenitor ...
Christine L. Trautmann, Adhideb Ghosh, Ali Kerem Kalkan, Falko Noé, Ori Bar‐Nur   +4 more
doaj   +1 more source