Rhabdomyolysis After Risperidone Overdose in a Patient With Schizophrenia: A Case Report. [PDF]
Neuropsychopharmacol RepABSTRACT A 50‐year‐old woman with schizophrenia overdosed on risperidone, lormetazepam, and lorazepam and subsequently developed rhabdomyolysis, with elevated creatine kinase (CK) and myoglobin levels. Intravenous treatment stabilized her condition. Risperidone was restarted at a regular dose, and rhabdomyolysis did not recur.
Takahashi J +5 more
europepmc +2 more sources
Top-Down Mass Analysis of Protein Tyrosine Nitration: Comparison of Electron Capture Dissociation with “Slow-Heating” Tandem Mass Spectrometry Methods [PDF]
, 2010 Tyrosine nitration in proteins is an important post-translational modification (PTM) linked to various pathological conditions. When multiple potential sites of nitration exist, tandem mass spectrometry (MS/MS) methods provide unique tools to locate the ...
Cooper, Helen J. +2 more
core +2 more sources
Sodium nitrite (NaNO2) regulating myoglobin-mediated lipid oxidation in washed bovine mince
International Journal of Food Properties, 2023 This study investigated the effect of NaNO2 on inhibiting myoglobin-mediated lipid oxidation in muscle using a washed bovine mince model. We measured various parameters, including TBARS and PV to determine lipid oxidation, non-heme iron release ...
Rongyu Zang +6 more
doaj +1 more source
Resonance Raman Interrogation of the Consequences of Heme Rotational Disorder in Myoglobin and its Ligated Derivatives [PDF]
, 2008 Resonance Raman spectroscopy is employed to characterize heme site structural changes arising from conformational heterogeneity in deoxyMb and ligated derivatives, i.e., the ferrous CO (MbCO) and ferric cyanide (MbCN) complexes.
Kincaid, James R. +2 more
core +3 more sources
Myoglobin-Catalyzed C-H Functionalization of Unprotected Indoles.
Angewandte Chemie, 2018 Functionalized indoles are recurrent motifs in bioactive natural products and pharmaceuticals. While transition metal-catalyzed carbene transfer has provided an attractive route to afford C3-functionalized indoles, these protocols are viable only in the ...
David A Vargas +3 more
semanticscholar +1 more source
Renormalization of myoglobin-ligand binding energetics by quantum many-body effects [PDF]
, 2014 We carry out a first-principles atomistic study of the electronic mechanisms of ligand binding and discrimination in the myoglobin protein. Electronic correlation effects are taken into account using one of the most advanced methods currently available ...
Cole, Daniel J. +3 more
core +3 more sources
ACS Applied Materials and Interfaces, 2016 We report the electrochemical detection of the redox active cardiac biomarker myoglobin (Mb) using aptamer-functionalized black phosphorus nanostructured electrodes by measuring direct electron transfer.
Vinod Kumar +20 more
semanticscholar +1 more source
Biomolecules, 2018 High-carbohydrate containing diets have become a precursor to glucose-mediated protein glycation which has been linked to an increase in diabetic and cardiovascular complications.
Hardik Ghelani +3 more
doaj +1 more source
Systematic screening of different polyglycerin‐based dienophile macromonomers for efficient nanogel formation through IEDDA inverse nanoprecipitation [PDF]
, 2019 Alternatives for strain‐promoted azide–alkyne cycloaddition (SPAAC) chemistries are needed because of the employment of expensive and not easily scalable precursors such as bicyclo[6.1.0]non‐4‐yne (BCN).
Haag, Rainer +2 more
core +1 more source
Intracellular oxygen tension limits muscle contraction-induced change in muscle oxygen consumption under hypoxic conditions during Hb-free perfusion. [PDF]
, 2017 Under acute hypoxic conditions, the muscle oxygen uptake (mV˙O2) during exercise is reduced by the restriction in oxygen-supplied volume to the mitochondria within the peripheral tissue. This suggests the existence of a factor restricting the mV˙O2 under
Furuichi, Yasuro +7 more
core +1 more source