Results 51 to 60 of about 43,668 (265)

Site-Directed Mutagenesis of Myoglobin for Studies of Their Interaction with Iron(III) by Multi-Spectroscopic Techniques

open access: yesJournal of Spectroscopy, 2013
In order to investigate how the amino acids on the surface of myoglobin molecule influence myoglobin's structure and function, a variety of spectroscopy techniques were applied in the study of the interaction between Fe(III) and myoglobin (wild type and ...
Qian Tang   +6 more
doaj   +1 more source

Paracetamol and its metabolites in children and adults with spinal muscular atrophy – a population pharmacokinetic model

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The aim of the study was to investigate whether differences in paracetamol pharmacokinetics (PK) between spinal muscular atrophy (SMA) patients and healthy controls (HC) could be attributed to specific clinical covariates. Methods Nonlinear mixed‐effects modelling (NONMEM 7.4) was used to develop a population PK model, explore covariates ...
Qiaolin Zhao   +14 more
wiley   +1 more source

Creatine: A valuable supplement in aquafeeds?

open access: yesReviews in Aquaculture, Volume 15, Issue 1, Page 292-304, January 2023., 2023
Abstract Creatine is an amino acid derivate commonly found in vertebrate muscle tissue. Creatine facilitates the recycling of adenosine triphosphate and thus contributes to the energy supply of the muscles as well as the brain. Creatine is used as a supplement for several reasons and its effects in humans, particularly in sports medicine, have been ...
Sven Wuertz, Stefan Reiser
wiley   +1 more source

Hemoadsorption therapy for myoglobin removal in rhabdomyolysis: consensus of the hemoadsorption in rhabdomyolysis task force

open access: yesBMC Nephrology
Background Rhabdomyolysis describes a syndrome characterized by muscle necrosis and the subsequent release of creatine kinase and myoglobin into the circulation.
Lui Forni   +18 more
doaj   +1 more source

Designing Enzymatic Reactivity with an Expanded Palette

open access: yesChemBioChem, EarlyView.
Innovation in biocatalysis is rapidly increasingly the diversity of catalytic reactivity that can be mediated by enzymes, addressing a key bottleneck for their widespread adoption in industrial chemical synthesis. A key approach to this is building enzymes with unnatural catalytic components that provide an expanded palette with new possibilities for ...
Reuben B. Leveson‐Gower
wiley   +1 more source

Aerobic high‐intensity intervals are superior to improve V̇O2max compared with sprint intervals in well‐trained men

open access: yesScandinavian Journal of Medicine &Science in Sports, Volume 33, Issue 2, Page 146-159, February 2023., 2023
Maximal oxygen uptake (V̇O2max) may be the single most important factor for long‐distance running performance. Interval training, enabling high intensity, is forwarded as the format that yields the largest increase in V̇O2max. However, it is uncertain if an optimal outcome on V̇O2max, anaerobic capacity, and running performance is provided by training ...
Håkon Hov   +6 more
wiley   +1 more source

Post Harvest Discoloration of Dark-Fleshed Fish Muscle: A Review

open access: yesWalailak Journal of Science and Technology, 2011
Discoloration of dark-fleshed fish species during storage and processing was mainly due to the reaction of myoglobin, a monomeric globular heme protein contributed to the pigmentation of red meat fish, alone and with other muscle components. Metmyoglobin
Manat CHAIJAN, Worawan PANPIPAT
doaj   +1 more source

Catalysis in Chemical Modification of Proteins

open access: yesChemCatChem, Accepted Article.
Advancement of catalytic transformations in traditional synthetic organic chemistry have made significant impacts on development of novel bioconjugation technologies. While a wide range of applications have become possible through catalytic protein bioconjugation approaches, there has been a lack of literature collectively reviewing advances of ...
Seiya Ishizawa   +4 more
wiley   +1 more source

Severe hyperferremia and hyperferritinemia in a dog with precursor‐directed immune‐mediated anemia

open access: yesVeterinary Clinical Pathology, Volume 51, Issue 4, Page 491-494, December 2022., 2022
Abstract A 4‐year‐old dog was evaluated at the Colorado State University Veterinary Teaching Hospital for lethargy and hyporexia of 24 hours duration. On presentation, she had a marked normocytic, normochromic, nonregenerative anemia (HCT 14%; RI 40–55).
Kristin M. Zersen   +3 more
wiley   +1 more source

Myoglobin clearance with continuous veno-venous hemodialysis using high cutoff dialyzer versus continuous veno-venous hemodiafiltration using high-flux dialyzer: a prospective randomized controlled trial

open access: yesCritical Care, 2020
Background Myoglobin clearance in acute kidney injury requiring renal replacement therapy is important because myoglobin has direct renal toxic effects.
Lorenz Weidhase   +5 more
doaj   +1 more source

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